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| 1 | Collision Tectonics between the Tarim Block(Basin)and the Northwestern Tibet Plateau:New Observations from a Multidisciplinary Geoscientific Investigation in the Western Kunlun Mountains显示文摘New results from deep seismic reflection profiling, wide-angle reflection-refraction profiling and broadband seismic experiments reveal that a series of south-dipping reflectors occur on the southern margin of the Tarim block (basin). However, it is these south-dipping structures that are intercepted by another series of north-dipping reflectors at depths from 30 to about 150 km beneath the foreland of the W Kunlun Mountains. No evidence from the above geophysical data as well as geochemical and surface geological data indicate the southward subduction of the Tarim block beneath the W Kunlun Mountains (NW Tibet plateau), forming the so-called “two-sided subduction” model for the Tibet plateau as proposed by previous studies. So the authors infer that the tectonic interaction between the Tarim block and the W Kunlun block was chiefly affected by a “horizontal compression in opposite directions”, which brought about “face-to-face contact” between these two lithospheric blocks and led to the thickening, shortening and densifying of the lithosphere. Hence a “delamination” was formed due to the gravitational instability created by the thickening and densifying; then alkaline basic volcanic rocks (mainly shoshonite series) was erupted along the northern margin of the Tibet plateau owing to the delamination. This inference for the formation of the alkaline basic volcanics has been confirmed by recent geochemical and petrological studies in Tibet, indicating that different contacts control different magmatic activities: the alkali basalts are always developed in the “horizontal shortening boundary (contact)” on the northern margin of the Tibet plateau, while the muscovite granite and two-mica granite (leucogranite) in the “subductional contact” on the southern margin of the Tibet plateau. | XIAO Xuchang LIU Xun GAO Rui Houn KAO LUO Zhaohua | 2001 | Acta Geologica Sinica(English Edition)2001，75，2： | 19 |
| 2 | Human-Tracking Strategies for a Six-legged Rescue Robot Based on Distance and View显示文摘Human tracking is an important issue for intelligent robotic control and can be used in many scenarios, such as robotic services and human-robot cooperation. Most of current human-tracking methods are targeted for mobile/tracked robots, but few of them can be used for legged robots. Two novel human-tracking strategies, view priority strategy and distance priority strategy, are proposed specially for legged robots, which enable them to track humans in various complex terrains. View priority strategy focuses on keeping humans in its view angle arrange with priority, while its counterpart, distance priority strategy, focuses on keeping human at a reasonable distance with priority. To evaluate these strategies, two indexes(average and minimum tracking capability) are defined. With the help of these indexes, the view priority strategy shows advantages compared with distance priority strategy. The optimization is done in terms of these indexes, which let the robot has maximum tracking capability. The simulation results show that the robot can track humans with different curves like square, circular, sine and screw paths. Two novel control strategies are proposed which specially concerning legged robot characteristics to solve human tracking problems more efficiently in rescue circumstances. | PAN Yang GAO Feng QI Chenkun CHAI Xun | 2016 | Chinese Journal of Mechanical Engineering2016，29，2： | 17 |
| 3 | Method for Six-Legged Robot Stepping on Obstacles by Indirect Force Estimation显示文摘Adaptive gaits for legged robots often requires force sensors installed on foot-tips,however impact,temperature or humidity can affect or even damage those sensors.Efforts have been made to realize indirect force estimation on the legged robots using leg structures based on planar mechanisms.Robot Octopus III is a six-legged robot using spatial parallel mechanism(UP-2UPS) legs.This paper proposed a novel method to realize indirect force estimation on walking robot based on a spatial parallel mechanism.The direct kinematics model and the inverse kinematics model are established.The force Jacobian matrix is derived based on the kinematics model.Thus,the indirect force estimation model is established.Then,the relation between the output torques of the three motors installed on one leg to the external force exerted on the foot tip is described.Furthermore,an adaptive tripod static gait is designed.The robot alters its leg trajectory to step on obstacles by using the proposed adaptive gait.Both the indirect force estimation model and the adaptive gait are implemented and optimized in a real time control system.An experiment is carried out to validate the indirect force estimation model.The adaptive gait is tested in another experiment.Experiment results show that the robot can successfully step on a 0.2 m-high obstacle.This paper proposes a novel method to overcome obstacles for the six-legged robot using spatial parallel mechanism legs and to avoid installing the electric force sensors in harsh environment of the robot's foot tips. | XU Yilin GAO Feng PAN Yang CHAI Xun | 2016 | Chinese Journal of Mechanical Engineering2016，29，4： | 16 |
| 4 | Mechanisms of improvement of left ventricle remodeling by transplanting two kinds of autologous bone marrow stem cells in pigs显示文摘背景在尖锐心肌的梗塞( AMI )以后的很多心肌的房间的坏死导致心脏的功能和移植能改进的室 remodeling.Stem 房间的减少在 AMI 以后的心脏的功能,但是包含的机制一直不是完全学习试图在改变的室上经由冠的动脉调查自体同源的骨头髓 mononuclear 房间( BM-MNC )和 rnesenchymal 干细胞( MSC )的移植的效果的在场的 understood.The 控制组,简单梗塞模型组, BM-MNC 移植组,和 MSC 移植当有 AMI 的一个缩小的猪的模型被建立时, 90 纪录的 group.At ,自体同源的 BM-MNC 的移植(( 4.7ntraoperative ,并且手术后)被评估, compared.The 病态和死亡结果在二 groups.The 后续结果被比较,在二组织的 surgery.Results 与外科手术前的高风险的侧面有病人的类似的百分比以后。 | LI Shu-ren QI Xiao-yong HU Fu-li ZHANG Jian-qing WANG Tian-hong DANG Yi MENG Cun-liang LIU Hui-liang LI Ying-xiao WU Di DONG Jie XUN Li-ying GAO Li-hui JIN Fu-chang | 2008 | Chinese Medical Journal2008，，23： | 12 |
| 5 | Response gene to complement 32 (RGC-32) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4显示文摘补充 32 的反应基因(RGC-32 ) 是涉及房间的增长,区别和迁居的一个房间周期管理者并且也在 angiogenesis 被含有。这里,我们证明在巨噬细胞的那 RGC-32 表情被 IL-4 导致并且由 LPS 减少了,显示在 RGC-32 表示和 M2 极化之间的一个连接。我们证明 RGC-32 的增加的表示或者激活的巨噬细胞,这蛋白质在压制支持 inflammatory cytokine IL-6 的生产并且支持反煽动性的调停人 TGF-β 的生产是特征的;。与一致在 vitro,数据, RGC-32 高级的联系肿瘤的巨噬细胞(TAM ) 快车,和这个表达式被导出肿瘤的腹水的液体以一种 M-CSF- 或 IL-4-dependent 方式导致。一起,这些结果为 M2 巨噬细胞极化作为一个标记建立 RGC-32 并且显示这蛋白质是为癌症免疫疗法的一个潜在的目标,指向联系肿瘤的巨噬细胞。 | Peng Zhao Daiqing Gao Qingjie Wang Bingfeng Song Qianqian Shao Jintang Sun Chunyan Ji Xingang Li Peng Li Xun Qu | 2015 | Cellular & Molecular Immunology2015，12，6： | 12 |
| 6 | Modeling and Robust Backstepping Sliding Mode Control with Adaptive RBFNN for a Novel Coaxial Eight-rotor UAV显示文摘This paper focuses on the robust attitude control of a novel coaxial eight-rotor unmanned aerial vehicles(UAV) which has higher drive capability as well as greater robustness against disturbances than quad-rotor UAV. The dynamical and kinematical model for the coaxial eight-rotor UAV is developed, which has never been proposed before. A robust backstepping sliding mode controller(BSMC) with adaptive radial basis function neural network(RBFNN) is proposed to control the attitude of the eightrotor UAV in the presence of model uncertainties and external disturbances. The combinative method of backstepping control and sliding mode control has improved robustness and simplified design procedure benefiting from the advantages of both controllers. The adaptive RBFNN as the uncertainty observer can effectively estimate the lumped uncertainties without the knowledge of their bounds for the eight-rotor UAV. Additionally, the adaptive learning algorithm, which can learn the parameters of RBFNN online and compensate the approximation error, is derived using Lyapunov stability theorem. And then the uniformly ultimate stability of the eight-rotor system is proved. Finally, simulation results demonstrate the validity of the proposed robust control method adopted in the novel coaxial eight-rotor UAV in the case of model uncertainties and external disturbances. | Cheng Peng Yue Bai Xun Gong Qingjia Gao Changjun Zhao Yantao Tian | 2015 | IEEE/CAA Journal of Automatica Sinica2015，2，1： | 10 |
| 7 | Analysis of the element content in poplar tree leaves by femtosecond laser-induced breakdown spectroscopy显示文摘Femtosecond laser-induced breakdown spectroscopy (fs-LIBS) is employed to analyze the element content in poplar tree leaves from four representative locations in Changchun City (Jingyue National Forest Park,JYP),Changchun University of Science and Technology (CUST),Casting Factory (CF) and Forging Factory (FF) of First Automobile Works (FAW) under identical experimental conditions.Those elements of N,P,K,Ca,Fe,Ti,Mn and Na are identified in the poplar tree leaves from the recorded spectrogram and the elemental content in the leaves is further obtained by applying free calibration method to the spectrogram.Our results show that the elements Ca and Fe in the poplar tree leaves from the CF area have the highest concentration in the four locations,which is a factor of 2.05 and 1.66 respectively to those of JYP.This experiment demon-strates that fs-LIBS can be utilized to analyze element content in a sample and find new applications in the environmental detection. | MA Shuang GAO Xun GUO KaiMin KAHSAY Medhanie LIN JingQuan | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，11： | 8 |
| 8 | The Crustal Structure and Assembly of Terranes in the Qaidam-Qilian-Beishan Area, Western China显示文摘Through a study of the geotransect from Golmud to Ejin Qi published recently, the tectonics of the crust beneath the area from the northern Qinghai-Tibet plateau (Qaidam and the Qilian Mountains) to the border between China and Mongolia and its structure, composition and tectonic evolution have been revealed, and abundant information about the deep structures has been provided. Based on the research into the geotransect, it is suggested that the crust in this area was formed by the assembly of the terranes in different geological stages. Following the formation of the Palaeo-Asian continent, the north part of the corridor of the transect became a part of the huge unifying continent by the end of the Early Permian. In the Mesozoic and Cenozoic, as a result of the compression mainly by the push of the Qinghai-Tibet plateau on the south, the unique crustal structure and geomorphologic features on the northern Qinghai-Tibet plateau were formed. This geotransect together with the Yadong-Golmud geotransect | LIU Xun GAO Rui | 1998 | Acta Geologica Sinica(English Edition)1998，72，3： | 7 |
| 9 | Obstacle avoidance for a hexapod robot in unknown environment显示文摘Obstacle avoidance is quite an important issue in the field of legged robotic applications, such as rescuing and detecting in complicated environment. Most related researchers focused on the legged robot’s gait generation after ssuming that obstacles have been detected and the walking path has been given. In this paper we propose and validate a novel obstacle avoidance framework for a six-legged walking robot Hexapod-III in unknown environment. Throughout the paper we highlight three themes: (1) The terrain map modeling and the obstacle detection; (2) the obstacle avoidance path planning method; (3) motion planning for the legged robot. Concretely, a novel geometric feature grid map (GFGM) is proposed to describe the terrain. Based on the GFGM, the obstacle detection algorithm is presented. Then the concepts of virtual obstacles and safe conversion pose are introduced. Virtual obstacles restrict the robot to walk on the detection terrain. A safe path based on Bezier curves, passing through safe conversion poses, is obtained by minimizing a penalty function taking into account the path length subjected to obstacle avoidance. Thirdly, motion planning for the legged robot to walk along the generated path is discussed in detail. At last, we apply the proposed framework to the Hexapod-III robot. The experimental result shows that our methodology allows the robot to walk safely without encountering with any obstacles in unknown environment. | CHAI Xun GAO Feng QI ChenKun PAN Yang XU YiLin ZHAO Yue | 2017 | Science China(Technological Sciences)2017，60，6： | 7 |
| 10 | Kinematics and trajectory planning of a cucumber harvesting robot manipulator显示文摘In order to reduce cucumber harvesting cost and improve economic benefits,a cucumber harvesting robot was developed.The cucumber harvesting robot consists of a vehicle,a 4-DOF articulated manipulator,an end-effector,an upper monitor,a vision system and four DC servo drive systems.The Kinematics of the cucumber harvesting robot manipulator was constructed using D-H coordinate frame model.And the inverse kinematics which provides a foundation for trajectory planning has been solved with inverse transform technique.The cycloidal motion,which has properties of continuity and zero velocity and acceleration at the ports of the bounded interval,was adopted as a feasible approach to plan trajectory in joint space of the cucumber harvesting robot manipulator.Moreover,hardware and software based on CAN-bus communication between the upper monitor and the joint controllers have been designed.Experimental results show that the upper monitor communicates with the four joint controllers efficiently by CAN-bus,and the integrated errors of four joint angles do not exceed four degrees.Probable factors resulting in the errors were analyzed and the corresponding solutions for improving precision are proposed. | Zhang Libin Wang Yan Yang Qinghua Bao Guanjun Gao Feng Xun Yi | 2009 | International Journal of Agricultural and Biological Engineering2009，2，1： | 7 |
| 11 | Synthesis and Crystal Structure of (E)-4-(Benzyloxy)-2-(cinnamoyloxy)-N,N,N-trimethyl-4-oxobutan-1-aminium Chloride as a Double-prodrug显示文摘A novel hydrochloride quaternary ammonium salt (E)-4-(benzyloxy)-2-(cinnamo- yloxy)-N,N,N-trimethyl-4-oxobutan-1-aminium chloride (C23H29NO4Cl2, Mr = 454.37) has been synthesized via the sequence of acetylation and esterification by using L-carnitine (L-4-N-trimethy- lammonium-3-hydroxybutyric acid, LC) and cinnamic acid as the starting materials, and its crystal structure was determined by single-crystal X-ray diffraction method. The crystal belongs to monoclinic, space group P212121 with a = 10.1670(4), b = 10.4488(4), c = 22.9795(11) ?, V = 2441.18(18) ?3, Z = 4, Dc = 1.236 g/cm3, μ(MoKα) = 0.293 mm?1, F(000) = 960, Flack factor = –0.01(11), the final R = 0.0489 and wR = 0.1550 for 3350 observed reflections (I > 2σ(I)) and R = 0.0953 for all 5648 unique reflections. The crystal structure involves a conjugated system which shows a reverse olefin structure. | GONG Xiao-Wei LI Xun LI Wei-Lu GAO Xu XU Wen-Fang ZHAI Hai-Min | 2008 | Chinese Journal of Structural Chemistry2008，27，2： | 6 |
| 12 | Managing esophageal fistulae by endoscopic transluminal drainage in esophageal cancer patients with superior mediastinal sepsis after esophagectomy显示文摘The management of postoperative leaks into the mediastinum after esophagectomy remains a challenge. We describe our clinical management of this complication through endoscopic transluminal drainage. Between 2008 and 2011, 4 patients with esophageal squamous cell carcinoma (ESCC) who underwent McKeown-type esophagectomy with two-field lymphadenectomy experienced complicated anastomotic fistulae in the presence of superior mediastinal sepsis. All 4 patients underwent endoscopic transluminal drainage, and all survived. The mean healing period was 50 days (range, 31 to 58 days), the mean stay in the intensive care unit was 7.3 days (range, 1 to 18 days), and the mean hospital stay was 64.5 days (range, 49 to 70 days). Endoscopically guided transluminal drainage should be considered for ESCC patients with superior mediastinal fistulae after esophagectomy. | Yu-Zhen Zheng Shu-Qin Dai Hong-Bo Shan Xiao-Yan Gao Lan-Jun Zhang Xun Cao Jian-Fei Zhu Jun-Ye Wang | 2013 | Chinese Journal of Cancer2013，32，8： | 6 |
| 13 | Molecular characteristics of three thymosin-repeat proteins from Marsupenaeus japonicus and their responses to WSSV infection显示文摘β-thymosins, a family of highly conserved peptides, play a vital role in wound-healing, angiogenesis,antimicrobial process and antiviral immunity. Three novel β-thymosin-repeat proteins, named mjthm4, mjthm3 and mjthm2, were cloned from Marsupenaeus japonicus using expressed sequence tags(EST) from suppression subtractive hybridization. The mjthm4, mjthm3 and mjthm2 c DNAs possessed open reading frames that encoded166, 128 and 90 amino acid residue polypeptides and contained four, three and two β-thymosin actin binding modules, respectively. Blast analysis demonstrated that mjthm4, mjthm3 and mjthm2 shared high homology with known invertebrate multi-repeat β-thymosins. These proteins are ubiquitously expressed in all of the examined tissues, and the transcriptional levels were highest in the intestine. Further investigation revealed that mjthm4,mjthm3 and mjthm2 were remarkably up-regulated 6 h after WSSV infection. Moreover, while mjthm4 transcriptional levels displayed no changes, mjthm3 and mjthm2 levels decreased in the virus-resistant shrimps.The results indicate that mjthm4, mjthm3 and mjthm2 are novel multi-repeat β-thymosin homologues, have a close relationship with WSSV infection, and might contribute to a better understanding of host defense and/or virus invasion interactions in shrimps. | MA Jinyou RUAN Lingwei XU Xun GAO Zhaoming | 2016 | Acta Oceanologica Sinica2016，35，4： | 5 |
| 14 | Antagonism of Protease-Activated Receptor 4 Protects Against Traumatic Brain Injury by Suppressing Neuroinflammation via Inhibition of Tab2/NF-κB Signaling显示文摘Traumatic brain injury(TBI)triggers the activation of the endogenous coagulation mechanism,and a large amount of thrombin is released to curb uncontrollable bleeding through thrombin receptors,also known as protease-activated receptors(PARs).However,thrombin is one of the most critical factors in secondary brain injury.Thus,the PARs may be effective targets against hemorrhagic brain injury.Since the PAR1 antagonist has an increased bleeding risk in clinical practice,PAR4 blockade has been suggested as a more promising treatment.Here,we explored the expression pattern of PAR4 in the brain of mice after TBI,and explored the effect and possible mechanism of BMS-986120(BMS),a novel selective and reversible PAR4 antagonist on secondary brain injury.Treatment with BMS protected against TBI in mice.mRNA-seq analysis,Western blot,and qRT-PCR verification in vitro showed that BMS significantly inhibited thrombin-induced inflammation in astrocytes,and suggested that the Tab2/ERK/NF-κB signaling pathway plays a key role in this process.Our findings provide reliable evidence that blocking PAR4 is a safe and effective intervention for TBI,and suggest that BMS has a potential clinical application in the management of TBI. | Jianing Luo Xun Wu Haixiao Liu Wenxing Cui Wei Guo Kang Guo Hao Guo Kai Tao Fei Li Yingwu Shi Dayun Feng Hao Yan Guodong Gao Yan Qu | 2021 | Neuroscience Bulletin2021，37，2： | 5 |
| 15 | Gas chromatography-mass spectrometry method for determination ofβ-propiolactone in human inactivated rabies vaccine and its hydrolysis analysis显示文摘A simple method was established for the determination of β-propiolactone(BPL) in human inactivated rabies vaccine by gas chromatography-mass spectrometry(GC-MS). The determination was performed on an Agilent HP-INNOWAX(30 m ? 0.32 mm i.d., 0.25 mm) capillary column at the temperature of 80 °C.Electrospray ionization(ESI) was used by selective ion detection at m/z 42. The temperature for ESI source and inlet was set at 230 °C and 200 °C, respectively. Helium was used as the carrier gas at a flow rate of 25.1 m L/min. The total run time was 8 min. Acetonitrile and other components in the sample did not interfere with the determination of BPL. The results showed good linearity of BPL in the range of0.50–10.01 μg/mL, with the limit of detection and the limit of quantification of 0.015 μg/mL and0.050 μg/mL, respectively. Satisfactory precision was achieved for the current developed method. The method was applied to detect 6 batches of vaccine samples, and the results indicated that the target analyte BPL was present in three batches of unpurified samples, but was not detected in the purified samples, indicating the test samples were qualified. The established method was proved to be simple,versatile and sensitive, which can meet the requirements of quality control of BPL in human inactivated rabies vaccine. | Shuo Lei Xun Gao Yang Sun Xiangyong Yu Longshan Zhao | 2018 | Journal of Pharmaceutical Analysis2018，8，6： | 5 |
| 16 | Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma显示文摘We sought to examine the regulatory effect of Meteorin-β(Metrnβ)/Meteorin like(Metrnl)/IL-41 on lung inflammation in allergic asthma.We found that Metrnβwas elevated significantly in asthmatic patients and in mice with allergic asthma induced by house dust mite(HDM)extract.Upon exposure to HDM,Metrnβwas secreted predominantly by airway epithelial cells and inflammatory cells,including macrophages and eosinophils.The increased Metrnβeffectively blocked the development of airway hyperreactivity(AHR)and decreased inflammatory cell airway infiltration and type 2 cytokine production,which was associated with downregulated DC-mediated adaptive immune responses.Moreover,Metrnβimpaired the maturation and function of bone marrow-derived dendritic cells in vitro.Asthmatic mice adoptively transferred with dendritic cells isolated from Metrnβ-treated allergic mice displayed decreased AHR,airway inflammation,and lung injury.Metrnβalso displayed anti-inflammatory properties in immunodeficient SCID mice with allergic asthma and in in vitro 3D ALI airway models.Moreover,blockade of Metrnβby anti-Metrnβantibody treatment promoted the development of allergic asthma.These results revealed the unappreciated protective roles of Metrnβin alleviating DC-mediated Th2 inflammation in allergic asthma,providing the novel treatment strategy of therapeutic targeting of Metrnβin allergic asthma. | Xun Gao Ting-Fan Leung Gary Wing-Kin Wong Wing-Hung Ko Mengyun Cai Ellie Jiayi He Ida Miu-Ting Chu Miranda Sin-Man Tsang Ben Chung-Lap Chan Jiawei Ling Xiao Fan Liwei Lu Christopher Wai-Kei Lam Chun-Kwok Wong | 2022 | Cellular & Molecular Immunology2022，19，2： | 5 |
| 17 | Characteristics of ion debris from laser-produced tin plasma and mitigation of energetic ions by ambient gas显示文摘极端紫外平版印刷术为下一代平版印刷术是很有希望的。然而,从生产激光的血浆的碎片,特别地精力充沛的离子,严重地减少极端紫外光学的一生。我们从听血浆测量了离子的特征等到有加倍频率的 Nd 的飞行方法:在 3.5O | YingBo Sun JingQuan Lin Xun Gao ZhenMing Zhao | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，3： | 4 |
| 18 | A decoupled procedure for convection-radiation simulation in scramjets显示文摘Following an order analysis of key parameters, a decoupled procedure for simulation of convection-radiation heat transfer problems in supersonic combustion ramjet(scramjet) engine was developed. The radiation module of the procedure consisted of Perry 5GG weighted sum gray gases model for spectral property calculation and discrete ordinates method S4 scheme for radiative transfer computation, while the flow field was computed using the Favrè average conservative Navier-Stokes(N-S) equations, in conjunction with Menter's k-ω SST two-equation model. A series of 2D supersonic nonreactive turbulent channel flows of radiative participants with selective parameters were simulated for validation purpose. Radiative characteristics in DLR hydrogen fueled and NASA SCHOLAR ethylene fueled scramjets were numerically studied using the developed procedure. The results indicated that the variations of spatial distributions of the radiative source and total absorption coefficient are highly consistent with those of the temperature and radiative participants, while the spatial distribution of the incident radiation spreads wider. It also demonstrated that the convective heating is significantly affected by the complexity of the flow field, such as the shock wave/boundary layer interactions, while the radiative heating is simply an integral effect of the whole flow field. Although the radiative heating in the combustion chambers reaches a certain level, an order of magnitude of 10 k W/m2, it still contributes little to the total heat transfer(<7%). | WANG Jing Ying GAO Zhen Xun LEE Chun Hian ZHANG Hui Qiang | 2014 | Science China(Technological Sciences)2014，57，12： | 4 |
| 19 | U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control study in Chinese population显示文摘在由维持 chromosomal 正直并且阻止染色体的生物变老的一个关键角色结束的 Telomeres 玩熔化。流行病学的研究建议了 telomere 长度的内部个人的差别能影响倾向到多重癌症,但是关于食道的有鳞的房间癌(ESCC ) 的证据仍然是不明确的。几 telomere 在白种人的长度相关的单个核苷酸多型性(TLSNP ) 在染色体宽的协会研究被报导了。然而,在 ESCC 开发的 telomere 长度和 TL-SNPs 的效果是不清楚的。因此,我们进行了盒子控制研究(1045 个 ESCC 案例和 1433 控制) 在中国人口评估在 telomere 长度, TL-SNPs,和 ESCC 风险之间的协会。作为结果, ESCC 案例显示出全面更短的相对 telomere 长度(RTL )( 中部:1.34 ) 比控制(中部:1.50, P < 0.001 ) 。更有趣地,一个明显的非线性的U字形的协会在 RTL 和 ESCC 风险之间被观察( P < 0.001 )与比率(95%信心间隔)等于到 2.40 的机会( 1.843.14 ), 1.36 ( 1.031.79 ), 1.01 ( 0.761.35 ),并且 1.37 ( 1.031.82 )为个人在第一(最短),第二,第三,并且 第5 (最长) quintile 分别地,在是的 第4 quintile 与那些相比引用组。没有重要协会在八报导 TL-SNPs 和 ESCC 危险性之间被观察。这些调查结果建议短或极其长的 telomeres 可以是为在中国人口的 ESCC 的风险因素。 | Jiangbo Du Wenjie Xue Yong Ji Xun Zhu Yayun Gu Meng Zhu Cheng Wang Yong Gao Juncheng Dai Hongxia Ma Yue Jiang Jiaping Chen Zhibin Hu Guangfu Jin Hongbing Shen | 2015 | Frontiers of Medicine2015，9，4： | 4 |
| 20 | Wafer-level and highly controllable fabricated silicon nanowire transistor arrays on (111) silicon-on-insulator (SOl) wafers for highly sensitive detection in liquid and gaseous environments显示文摘 | Xun Yang Anran Gao Yuelin Wang Tie Li | 2018 | Nano Research2018，11，3： | 4 |
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