|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 在没有危险因素的情况下,正常的低密度脂蛋白胆固醇水平与亚临床动脉粥样硬化相关显示文摘普遍认为缺乏心血管病危险因素(cardiovascular risk factors,CVRF)人群的动脉粥样硬化发生风险低,然而,无CVRF的个体仍然有心血管事件发生。为了确定无CVRF个体中亚临床动脉粥样硬化的预测因子, | Fernández-Friera L Fuster V López-Melgar B Oliva B García-Ruiz JM Mendiguren J Bueno H Pocock S Ibánez B Fernández-Ortiz A Sanz J 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，12： | 17 |
| 2 | Subclinical abnormal glucose tolerance is a predictor of death in liver cirrhosis显示文摘AIM:To determine if subclinical abnormal glucose tolerance(SAGT)has influence on survival of non-diabetic patients with liver cirrhosis.METHODS:In total,100 patients with compensatedliver cirrhosis and normal fasting plasma glucose were included.Fasting plasma insulin(FPI)levels were measured,and oral glucose tolerance test(OGTT)was performed.According to OGTT results two groups of patients were formed:those with normal glucose tolerance(NGT)and those with SAGT.Patients were followed every three months.The mean follow-up was932 d(range of 180-1925).Survival was analyzed by the Kaplan-Meyer method,and predictive factors of death were analyzed using the Cox proportional hazard regression model.RESULTS:Of the included patients,30 showed NGT and70 SAGT.Groups were significantly different only in age,INR,FPI and HOMA2-IR.Patients with SAGT showed lower 5-year cumulated survival than NGT patients(31.7%vs 71.6%,P=0.02).Differences in survival were significant only after 3 years of follow-up.SAGT,Child-Pugh B,and high Child-Pugh and Model for EndStage Liver Disease(MELD)scores were independent predictors of death.The causes of death in 90.3%of cases were due to complications related to liver disease.CONCLUSION:SAGT was associated with lower survival.SAGT,Child-Pugh B,and high Child-Pugh and MELD scores were independent negative predictors of survival. | Diego García-Compeán Joel Omar Jáquez-Quintana Fernando Javier Lavalle-González José Alberto González-González Linda Elsa Mu?oz-Espinosa Jesús Zacarías Villarreal-PérezEndocrinology Service and Department of Internal Medicine University Hospital 'Dr. José E. González' and Medical School Universidad Autónoma de Nuevo León Monterrey 64320 México Héctor J Maldonado-Garza | 2014 | World Journal of Gastroenterology2014，20，22： | 12 |
| 3 | Hepatogenous diabetes: Is it a neglected condition in chronic liver disease?显示文摘Diabetes mellitus(DM) that occurs because of chronic liver disease(CLD) is known as hepatogenous diabetes(HD). Although the association of diabetes and liver cirrhosis was described forty years ago, it was scarcely studied for long time. Patients suffering from this condition have low frequency of risk factors of type 2 DM. Its incidence is higher in CLD of viral, alcoholic and cryptogenic etiology. Its pathophysiology relates to liver damage, pancreatic dysfunction, interactions between hepatitis C virus(HCV) and glucose metabolism mechanisms and genetic susceptibility. It associates with increased rate of liver complications and hepatocellular carcinoma, and decreased 5-year survival rate. It reduces sustained virological response in HCV infected patients. In spite of these evidences, the American Diabetes Association does not recognize HD. In addition, the impact of glucose control on clinical outcomes of patients has not been evaluated. Treatment of diabetes may be difficult due to liver insufficiency and hepatotoxicity of antidiabetic drugs. Notwithstanding, no therapeutic guidelines have been implemented up to date. In this editorial, authors discuss the reasons why they think that HD may be a neglected pathological condition and call attention to the necessity for more clinical research on different fields of this disease. | Diego García-Compeán José Alberto González-González Fernando Javier Lavalle-González Emmanuel Irineo González-Moreno Jesús Zacarías Villarreal-Pérez Héctor Jesús Maldonado-Garza | 2016 | World Journal of Gastroenterology2016，22，10： | 12 |
| 4 | 墨西哥红豆杉愈伤组织的诱导和器官发生显示文摘 | 肖尊安 Héctor Barrios Consuelo Sandoval Garc姫a | 2000 | 植物生理学通讯2000，36，6： | 9 |
| 5 | Diagnostic and therapeutic challenges of gastrointestinal angiodysplasias: A critical review and view points显示文摘Gastrointestinal angiodysplasias (GIADs), also called angioectasias, are the most frequent vascular lesions. Its precise prevalence is unknown since most of them are asymptomatic. However, the incidence may be increasing since GIADs affect individuals aged more than 60 years and population life expectancy is globally increasing worldwide. They are responsible of about 5% to 10% of all gastrointestinal bleeding (GIB) cases. Most GIADs are placed in small bowel, where are the cause of 50 to 60% of obscure GIB diagnosed with video capsule endoscopy. They may be the cause of fatal severe bleeding episodes;nevertheless, recurrent overt or occult bleeding episodes requiring repeated expensive treatments and disturbing patient’s quality-of-life are more frequently observed. Diagnosis and treatment of GIADs (particularly those placed in small bowel) are a great challenge due to insidious disease behavior, inaccessibility to affected sites and limitations of available diagnostic procedures. Hemorrhagic causality out of the actively bleeding lesions detected by diagnostic procedures may be difficult to establish. No treatment guidelines are currently available, so there is a high variability in the management of these patients. In this review, the epidemiology and pathophysiology of GIADs and the status in the diagnosis and treatment, with special emphasis on small bowel angiodysplasias based on multiple publications, are critically discussed. In addition, a classification of GIADs based on their endoscopic characteristics is proposed. Finally, some aspects that need to be clarified in future research studies are highlighted. | Diego García-Compeán ángel N Del Cueto-Aguilera Alan R Jiménez-Rodríguez José A González-González Héctor J Maldonado-Garza | 2019 | World Journal of Gastroenterology2019，25，21： | 5 |
| 6 | The use of VR in the treatment of panic disorders and agoraphobia显示文摘 | Botella C Villa H García Palacios A | | 0，，： | 1 |
| 7 | Reconfigurable distributed control using smart peripheral elements显示文摘 | Benítez-Pérez H García-Nocetti F | 2003 | Control Engineering Practice2003，11，9： | 1 |
| 8 | Applications for bronchial blockers in thoracic surgery显示文摘 | GARC(I)A-GUASCH R CAMPOS J H GRANELL M | | 0，，09： | 1 |
| 9 | COMT gene and risk for Parkinson's disease:a systematic review and meta-analysis显示文摘 | Jiménez-Jiménez FJ Alonso-Navarro H García-Martín E | 2014 | Pharmacogenet Genomics2014，24，7： | 1 |
| 10 | A fresh look at reperfusion injury显示文摘 | Piper H M García-Dorado D Ovize M | 1998 | Cardiovascular Research1998，38，： | 1 |
| 11 | The effect of the parenteral route of administration on the immune response to simultaneous nasal and parenteral immunizations using a new HBV therapeutic vaccine candidate显示文摘 | Lobaina Y Trujillo H García D | 2010 | Viral Immunol2010，23，5： | 1 |
| 12 | A combined electrochemical and theoretical study of N,N′bis(benzimidazole2ylethyl)1,2diaminoethane as a new corrosion inhibitor for carbon steel surface显示文摘 | Guadalupe H J GarcíaOchoa E MaldonadoRivas P J | 2011 | Journal of Electroanalytical Chemistry2011，655，2： | 1 |
| 13 | Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation,oxidative stress and tau-phosphorylation for Alzheimer's disease显示文摘 | García-Font N Hayour H Belfaitah A | 2016 | European Journal of Medicinal Chemistry2016，118，： | 1 |
| 14 | Detection of Iberian ham aroma by a semiconductor multisen sorial system显示文摘 | Otero L Ma Carmen H Garc M | 2003 | Meat Science2003，，65： | 1 |
| 15 | Heterogeneous Gif oxidation of cyclohexane using Fe^3+ -picoli nate complex encapsulated within zeolites显示文摘 | IVARO M FERRER B GARC H | 1999 | Tetrahe-dron1999，55，11： | 1 |
| 16 | In vivo intravascular ultrasound-derived thin-cap fibroatheroma detection using ultrasound radiofrequency data analysis显示文摘 | RODRIGUEZ-GRANILLO G A GARCA-GARCA H M MC FADDEN E P | 2005 | J Am Coll Cardiol2005，46，： | 1 |
| 17 | Acoustics today显示文摘 | Bass H E Bhattacharyya J Garces M A | 2006 | Acoustical Society of America2006，，2： | 1 |
| 18 | Mean flow and turbulence structure of open-channel flow through non-emergent vegetation显示文摘 | López F García M H | 2001 | Journal of Hydraulic Engineering2001，127，5： | 1 |
| 19 | Gene expression changes induced by Ochratoxin A in renal and hepatic tissues of male F344 rat after oral repeated administration显示文摘 | Arbillaga L Vettorazzi A Gil A G Delft J H García-Jalón J A Cerain A L | 2008 | Toxicology and Applied Pharmacology2008，230，2： | 1 |
| 20 | Pollen biology in four Mediterranean Quercus species显示文摘 | Teresa Gómez-Casero M T Hidalgo P J García-Mozo H Dominguez E Galán C | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员