|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Global secretome analysis identifies novel mediators of bone metastasis显示文摘骨头是稳固的肿瘤的远转移的一个最普通的地点。分泌蛋白质被知道影响在变形癌症房间和骨头基质之间的病理学的相互作用。为了包括地介绍,分泌了与骨头转移联系的蛋白质,我们使用了量、非量的集体 spectrometry 全球性分析改变从多重种类和癌症的变形能力打的骨头的九根细胞线的 secretomes。由比较父母房间和他们的骨头的 secretomes 变形衍生物,我们识别了特别地在这些房间线与骨头转移被联系的分泌蛋白质。我们然后合并了大临床的转移数据集的生物信息的分析获得强烈与临床、试验性的骨头转移被联系的几个功能的班的候选人小说骨头转移蛋白质的一张表。选择蛋白质的功能的确认显示在 vivo,骨头转移能被高表示支持(1 ) 唾液的 cystatins CST1, CST2,和 CST4;(2 ) plasminogen 使活跃之物小块地和 PLAU;或(3 ) 骨胶原功能蛋白质 PLOD2 和 COL6A1。总的来说,我们的学习揭开了骨头转移并且因此的几个新分泌调停人证明 secretome 分析是为新奇 biomarkers 和候选人的鉴定的一个强大的方法治疗学的目标。 | Maria Andres Blanco Gary LeRoy Zia Khan Ma a Ale kovi Barry M Zee Benjamin A Garcia Yibin Kang | 2012 | Cell Research2012，22，9： | 12 |
| 2 | 尿酸是正常高值血压发展为高血压的一个重要危险标志物显示文摘正常高值血压常发展为高血压,是一个与心血管病和脑卒中高死亡率和高发病率相关的事件。然而,正常高值血压发展成高血压的危险因素仍不清楚。研究者采用年龄(52.1±11.0)岁日本成年高血压患者3584例(2081例为男性)的资料进行前瞻性群体研究,研究对象在2004年被发现处于正常高值血压阶段,并在2009年重新进行检查。 | 黄洁 叶鹏 Kuwabara M Hisatome I Niwa K Hara S Roncal-Jimenez CA Bjornstad P Nakagawa T Andres-Hernando A Sato Y Jensen T Garcia G Rodriguez-Iturbe B Ohno M Lanaspa MA Johnson RJ | 2017 | 中华高血压杂志2017，25，12： | 2 |
| 3 | A robust soc-MOF platform exhibiting high gravimetric uptake and volumetric deliverable capacity for on-board methane storage显示文摘Emerging as an outperformed class of metal-organic frameworks(MOFs),square-octahedron(soc)topology MOFs(soc-MOFs)feature superior properties of high porosity,large gas storage capacity,and excellent thermal/chemical stability.We report here an iron based soc-MOF,denoted as Fe-pbpta(H4pbpta=4,4',4'',4'''-(1,4-phenylenbis(pyridine-4,2-6-triyl))-tetrabenzoic acid)possessing a very high Brunauer,Emmett and Teller(BET)surface area of 4,937 m2/g and a large pore volume of 2.15 cm3/g.The MOF demonstrates by far the highest gravimetric uptake of 369 cm3(STP)/g under the DOE operational storage conditions(35 bar and 298 K)and a high volumetric deliverable capacity of 192 cc/cc at 298 K and 65 bar.Furthermore,Fe-pbpta exhibits high thermal and aqueous stability making it a promising candidate for on-board methane storage. | Gaurav Verma Sanjay Kumar Harsh Vardhan Junyu Ren Zheng Niu Tony Pham Lukasz Wojtas Sydney Butikofer Jose C Echeverria Garcia Yu-Sheng Chen Brian Space and Shengqian Ma | 2021 | Nano Research2021，14，2： | 2 |
| 4 | Cloning, sequencing, and expression of a cDNA encoding rat LIMP II, a novel 74-kDa lysosomal membrane protein related to the surface adhesion protein CD36显示文摘 | Vega MA Segui-Real B Garcia JA | 1991 | J Biol Chem1991，266，16： | 1 |
| 5 | Prognostic value of bronchiectasis in patients with moderate - to - se- vere chronic obstructive pulmonary disease显示文摘 | Martinez - Garcia MA de la Rosa CD Soler - Cataluna JJ | 2013 | Am J Respir Crit Care Med2013，187，8： | 1 |
| 6 | Guidelines on the management of stable angina pectoris:executive summary:the Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology显示文摘 | Fox K Garcia MA Ardissino D | 2006 | Eur Heart J2006，27，： | 1 |
| 7 | Esti- mating risk for suicide attempt: Are we asking the right questions? Pas- sive suicidal ideation as a marker for suicidal behavior显示文摘 | Baca - Garcia E Perez - Rodriguez MM Oquendo MA | 2011 | J Affect Disord2011，134，13： | 1 |
| 8 | Predictors of left atrial spontaneous echo contrast and thrombi in patients with mitral stenosis and atrial fibrillation显示文摘 | Gonzalez-torrecilla E Garcia Fernadez MA Peraz David E | 2000 | Am J Cadiol2000，86，5： | 1 |
| 9 | An index of early left ventricular filling that combined with pulsed Doppler peak E velocity may estimate capillary wedge pressure显示文摘 | Garcia MJ Ares MA Asher C | 1997 | J Am Coll Cardiol1997，29，2： | 1 |
| 10 | The new oral anticoagulants显示文摘 | Garcia D Libby E Ma C | 2010 | Blood2010，115，1： | 1 |
| 11 | Easy access to orthogonally protected α - alkyl aspartic acid and α - alkyl asparagine derivatives by controlled opening of β - lactams 显示文摘 | Guillermo Gerona - Navarro Ma Teresa Garcia - Lopez Rosario Gonzalez - Muniz | 2003 | Tetrahedron Letters2003，44，32： | 1 |
| 12 | Lipid addition to improve barrier properties of edible starch-based films and coatings显示文摘 | GARCIA MA MARTINO MN ZARITZKY NE | 2000 | Journal of Food Science2000，65，6： | 1 |
| 13 | Uric acid - induced endothelial dysfunction is associ- ated with mitochondrial alterations and decreased intracellu- lar ATP concentrations 显示文摘 | Sanchez - Lozada LG Lanaspa MA Cristobal - Garcia M | 2012 | Nephron Exp Nephrol2012，121，： | 1 |
| 14 | Association Between Colorectal Cancer Susceptibility Loci and Survival Time After Diagnosis With Colorectal Cancer显示文摘 | Amanda I. Phipps Polly A. Newcomb Xabier Garcia–Albeniz Carolyn M. Hutter Emily White Charles S. Fuchs Aditi Hazra Shuji Ogino Hongmei Nan Jing Ma Peter T. Campbell Jane C. Figueiredo Ulrike Peters Andrew T. Chan | 2012 | Gastroenterology2012，，1： | 1 |
| 15 | The new oral anticoagulants显示文摘 | GARCIA D LIBBY E CROWTHER MA | 2010 | Blood2010，115，1： | 1 |
| 16 | Male systemic lupus erythemato- sus in a Latin-American inception cohort of 1214 patients显示文摘 | Garcia MA Marcos JC Marcos AI | 2005 | Lupus2005，14，12： | 1 |
| 17 | Viral community acquimd2 pneumonia in nonimmunocompromised adults显示文摘 | Roux A Mareos MA Garcia E | 2004 | Chest2004，25，8： | 1 |
| 18 | A clinicaland magnetoencephalography study of MRI - negative startle epilepsy显示文摘 | Garcia - Morales I Maestii F P6rez - Jim#nez MA | 2009 | Epilepsy Behav2009，16，1： | 1 |
| 19 | Predictors of left atrial spontaneous echocontrast and thrombi in patients with mitral stenosis and atrial fibrillation显示文摘 | Gonzalez Torrecilla E Garcia Fernandez MA Perez David E | 2000 | Am J Cardiol2000，86，5： | 1 |
| 20 | Recombinant viruses expressing the foot-and-mouth disease virus capsid precursor polypeptide (P1) induce cellular but not humoral antiviral immunity and partial protection in pigs 显示文摘 | Sanz Parra A Jimenez Clavevo MA Garcia Briones MM | 1999 | Virology1999，259，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员