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		题名	作者	年代	出处	被引量
	1	Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes显示文摘	Brown CT Davis-Richardson AG Giongo A		0，，：	1
	2	Toward defining the autoi- mmune microbiome for type 1 diabetes显示文摘	Giongo A Gano KA Crabb DB	2011	ISME J2011，5，1：	1
	3	Esophagogastric junction outflow obstruction successfully treated with laparoscopic Heller myotomy and Dor fundoplication: First case report in the literature显示文摘BACKGROUND Esophagogastric junction outflow obstruction(EGJOO) is a rare syndrome,characterized by an elevation of the integrated relaxation pressure of the lower esophageal sphincter, not accompanied by alterations in esophageal motility that may lead to the criteria for achalasia. We were unable to find any prior report of the combination of Heller myotomy with anterior partial fundoplication(Dor) as the treatment for EGJOO. We herein report a case of EGJOO treated with laparoscopic Heller myotomy combined with Dor fundoplication.CASE SUMMARY A 26-year-old man presented with a 3-year history of solid dysphagia and a 30-kg weight loss. He was treated with oral nifedipine, isosorbide, and omeprazole,without resolution of symptoms. An upper gastrointestinal series(barium swallow) revealed a 'bird's beak' sign. Esophagogastroduodenoscopy was positive for Los Angeles grade A peptic esophagitis. High-resolution esophageal manometry was compatible with EGJOO. Esophageal pH monitoring showed pathological acid reflux both in orthostatic and decubitus position. An 8-cm laparoscopic Heller myotomy combined with an anterior 220° Dor fundoplication was performed. Solid diet was introduced on postoperative day 2, and the patient was discharged home the same day. At 17-mo follow-up, he reported no symptoms. Barium swallow was compatible with complete radiologic resolution.Both esophageal manometry and upper endoscopy showed normal findings 9 mo after the operation.CONCLUSION Surgical treatment with Heller myotomy and Dor fundoplication is a potential treatment option for EGJOO refractory to medical treatment.	Pedro F Pereira Andre RP Rosa Leonardo A Mesquita Marcelle J Anzolch Rafael N Branchi Augusto L Giongo Francisco C Paix?o Marcio F Chedid Cleber DP Kruel	2019	World Journal of Gastrointestinal Surgery2019，11，2：	1
	4	Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes 显示文摘	Brown CT Davis-Richardson AG Giongo A	2011	PLoS One2011，6，25：	1
	5	Toward definingthe autoimmune microbiome for type 1 diabetes 显示文摘	Giongo A Gano KA Crabb DB	2011	ISME2011，5，1：	1
	6	Toward defining the autoimmune microbiome for type 1 diabetes显示文摘	Giongo A Gano KA Crabb DB	2011	ISM E J2011，5，1：	1
	7	Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes显示文摘	BROWN C T RICHARDSON A G D GIONGO A	2011	PLoS ONE2011，6，25：	1
	8	Use of RAPD analysis to characterize Vaccinium accessions显示文摘	GIONGO L VENDRAM1N E QUARTA R DETTORI M T VERGE I BERGAMINI A	2006	Acta Hort2006，715，：	1
	9	Toward defining tautoimmunemicrobiome for type I diabetes显示文摘	Giongo A Gano KA CrabbDB	2011	International Society for MicrobialEcology2011，5，1：	1
	10	Toward defining the autoimmune microbiome for type 1 diabetes 显示文摘	Giongo A Gano KA erabb DB	2011	The ISME journal2011，5，1：	1
	11	Keratinolytic proteases of Bacillus species isolated from the Amazon basin showing remarkable de-hairing ac- tivity显示文摘	Giongo J L Lucas F S Casarin F Heeb P Brandelli A	2007	World Journal of Microbiology and Biotechnol- ogy2007，23，：	1
	12	Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes显示文摘	Brown CT Davis?Richardson AG Giongo A	2011	PLoS One2011，6，25：	1
	13	Toward defining the autoimmune microbiome for type 1 diabetes显示文摘	Giongo A Gano KA Crabb DB et at	2011	ISME J2011，5，1：	1
	14	Toward defining the autoimmune microbiome for type 1 diabetes显示文摘	Giongo A Gano KA Crabb DB	2011	ISME J2011，5，1：	1

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