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| 1 | Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine. | Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu | 2021 | World Journal of Transplantation2021，11，4： | 2 |
| 2 | Murine model to study brain,behavior and immunity during hepatic encephalopathy显示文摘AIM:To propose an alternative model of hepatic encephalopathy(HE) in mice,resembling the human features of the disease.METHODS:Mice received two consecutive intraperitoneal injections of thioacetamide(TAA) at low dosage(300 mg/kg).Liver injury was assessed by serum transaminase levels(ALT) and liver histology(hematoxylin and eosin).Neutrophil infiltration was estimated by confocal liver intravital microscopy.Coagulopathy was evaluated using prolonged prothrombin and partial thromboplastin time.Hemodynamic parameters were measured through tail cuff.Ammonia levels were quantified in serum and brain samples.Electroencephalography(EEG) and psychomotor activity score were performed to show brain function.Brain edema was evaluated using magnetic resonance imaging.RESULTS:Mice submitted to the TAA regime developed massive liver injury,as shown by elevation of serum ALT levels and a high degree of liver necrosis.An intense hepatic neutrophil accumulation occurred in response to TAA-induced liver injury.This led to mice mortality and weight loss,which was associated with severe coagulopathy.Furthermore,TAA-treated mice presented with increased serum and cerebral levels of ammonia,in parallel with alterations in EEG spectrum and discrete brain edema,as shown by magnetic resonance imaging.In agreement with this,neuropsychomotor abnormalities ensued 36 h after TAA,fulfilling several HE features observed in humans.In this context of liver injury and neurological dysfunction,we observed lung inflammation and alterations in blood pressure and heart rate that were indicative of multiple organ dysfunction syndrome.CONCLUSION:In summary,we describe a new murine model of hepatic encephalopathy comprising multiple features of the disease in humans,which may provide new insights for treatment. | Lindisley Ferreira Gomides Pedro Elias Marques Bruno Engler Faleiros Rafaela Vaz Pereira Sylvia Stella Amaral Thais Reis Lage Gustavo Henrique Souza Resende Patricia Alves Maia Guidine Giselle Foureaux Fabíola Mara Ribeiro Fabiana Paiva Martins Marco Antonio Peliky Fontes Anderson José Ferreira Remo Castro Russo Mauro Martins Teixeira Márcio Flávio Moraes Antonio Lúcio Teixeira Gustavo Batista Menezes | 2014 | World Journal of Hepatology2014，6，4： | 2 |
| 3 | Rapid Identification of Rhizobia by Restriction Fragment Length Ploymorphism Analysis of PCR-Amplified 16S rRNA Genes显示文摘 | Gisele L Marie-reine A Francoise R | 1994 | Appl Environ Microbiol1994，60，： | 1 |
| 4 | Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model 显示文摘 | Cal0n F Giselle L | 2004 | Neuron2004，43，5： | 1 |
| 5 | A bio-inspired Fe(Ⅲ) complex and its use in the cyclohexane oxidation显示文摘 | Giselle C S Gabrieli L P Nakedia M F | 2008 | Catal Today2008，，： | 1 |
| 6 | Chitosan-pectin multiparticulate systems associated with enteric polymers for colonic drug delivery显示文摘 | Oliveira Giselle F Ferrari Priscileila C Carvalho Lívia Q | 2010 | Carbohydrate Polymers2010，82，： | 1 |
| 7 | Quantitative analysis of trigonelline in some Annona species by proton NMR spectroscopy显示文摘A quantitative ^(1)H NMR method(qHNMR)was used to measure the trigonelline content in the leaves of six species of the Annona genus.The methodology employed compared the intensities of the signals at δ9.14(H-2)andδ0.00,the internal standard TSP-d_(4).This measuring method was able to establish the concentration of trigonelline in the range from 0.67 to 10.04 mg·g^(-1) depending on the investigated extract. | Alan Rodrigues Teixeira MACHADO Gisele Avelar LAGE Felipe da Silva MEDEIROS José Dias de Souza FILHO Lúcia Pinheiro Santos PIMENTA | 2013 | Natural Products and Bioprospecting2013，3，4： | 1 |
| 8 | Consensus-degenerate hybrid oligonucleotide primers for amplification of priming glycosyltransferase genes of the exopolysaccharide locus in strains of the lactobacillus casei group显示文摘 | Cathy PC Gisele L Stephane S | 2003 | Appl Environmental Microbiol2003，69，： | 1 |
| 9 | Rapid identification of rhizobia by restriction fragment length polymorphism analysis of PCR-amplified 16S rRNA genes显示文摘 | GISELE L MARIE-REINE A FRANCOISE R AMARGER N | 1994 | Applied and Environmental Microbiology1994，60，1： | 1 |
| 10 | In-capillary derivatization approach applied to the analysis of insulin by capillary electrophoresis with laser-induced fluorescence deteetion显示文摘 | ISABELLE L P GISELE F CLAIRE S | 2004 | Journal of Chromatography A2004，1046，12： | 1 |
| 11 | Frequency of urinary tract infection in catheterized dogs and comparison of bac- terial culture and susceptibility testing results for catheterized and noncatheterized dogs with urinary tract infections 显示文摘 | Loretta J Bubenik Giselle L Hosgood Don R Waldron | 2002 | Journal of the American Veterinary Medical Association2002，，31： | 1 |
| 12 | Patho- genic and opportunistic respiratory bacteria-induced apoptosis显示文摘 | Marcelo L Rafaella F C P Gisele G C | 2009 | The Brazilian Journal of Infectious Diseases2009，13，3： | 1 |
| 13 | Characterization and site-directed mutagenesis of Wzb,an O-phosphatase from Lactobacillus rhamnosus显示文摘 | Gisele L Daniele A Christophe G | 2008 | Biochemistry2008，9，10： | 1 |
| 14 | Prevention of Alzheimer' s disease: Omega-3 fatty acid andphenolic anti-oxidant interventions显示文摘 | GREG M C GISELLE P L FUSHENG Y | 2005 | Neurobiology of Aging2005，26，1： | 1 |
| 15 | Update on Assessment and Manage-ment of Dysphasia Post Stroke 显示文摘 | Giselle C Kerry L Michael A | 2013 | Northeast Florida Medicine2013，64，2： | 1 |
| 16 | A novel synthetic route for magnesium aluminate(Mg Al2O4)particles using metal-chitosan complexation method显示文摘 | Giselle D B Nuernberg Edson L Foletto Luiz F D Probst | 2012 | Chemical Engineering Journal2012，，： | 1 |
| 17 | Biochemical Properties of Recombinant Human and Mouse N-acetylglutamate Synthase 显示文摘 | CALDOVIC GISELLE Y L HASKINS N | 2006 | Mol Genet Metab2006，87，3： | 1 |
| 18 | Rapid identification of Rhizobia by restriction fragment length ploy- morphism analysis of PCR amplified 16S rRNA genes显示文摘 | Gisele L Marie reine A Francoise R | 1994 | Appl Environ Microbiol1994，60，1： | 1 |
| 19 | Testicular activity is restored by melatonin replacement after suprachiasmatic nucleus lesion or superior cervical ganglionectomy in mink显示文摘 | Daniel L Maurel Mohamed Moncef Ben Saad Gisele Roch l | 2002 | Pineal Research2002，32，1： | 1 |
| 20 | La reglette EVA: un outil de mediation dans la relation soignant - malade? Etude sociologique realisee dans deux centres specialises dans le traitement du cancer de la region Rhene - Alpes 显示文摘 | Veronique Regnier Anne l efranc Gisele Chvetzoff David Perol Franck Chauvin | 2008 | Douleurs: Evaluation- Diagnostic- Traitement2008，，9： | 1 |
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