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| 1 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 2 | Value of a comprehensive geriatric assessment for predicting one-year outcomes in patients undergoing transcatheter aortic valve implantation: results from the CGA-TAVI multicentre registry显示文摘Background In a three-month report from the CGA-TAVI registry, we found the Multidimensional Prognostic Index (MPI) and Short Physical Performance Battery (SPPB) to be of value for predicting short-term outcomes in elderly patients undergoing transcatheter aortic valve implantation (TAVI). In the present analysis, we examined the association of these tools with outcomes up to one year post-TAVI. Methods CGA-TAVI is an international, observational registry of geriatric patients undergoing TAVI. Patients were assessed using the MPI and SPPB. Efficacy of baseline values and any postoperative change for predicting outcome were established using logistic regression. Kaplan- Meier analysis was carried out for each comprehensive geriatric assessment tool, with survival stratified by risk category. Results One year after TAVI, 14.1% of patients deceased, while 17.4% met the combined endpoint of death and/or non-fatal stroke, and 37.7% the combined endpoint of death and/or hospitalisation and/or non-fatal stroke. A high-risk MPI score was associated with an increased risk of all-cause mortality (aOR = 36.13, 95% CI: 2.77–470.78, P = 0.006) and death and/or non-fatal stroke (aOR = 10.10, 95% CI: 1.48–68.75, P = 0.018). No significant associations were found between a high-risk SPPB score and mortality or two main combined endpoints. In contrast to a worsening SPPB, an aggravating MPI score at three months post-TAVI was associated with an increased risk of death and/or non-fatal stoke at one year (aOR = 95.16, 95% CI: 3.41–2657.01). Conclusions The MPI showed value for predicting the likelihood of death and a combination of death and/or non-fatal stroke by one year after TAVI in elderly patients. | Martijn S.van Mourik Nathalie van der Velde Giulio Mannarino Marie-Pierre Thibodeau Jean-Bernard Masson Gennaro Santoro Jan Baan Sofie Jansen Jana Kurucova Martin Thoenes Cornelia Deutsch ANDreas W.Schoenenberger ANDrea Ungar Peter Bramlage M Marije Vis | 2019 | Journal of Geriatric Cardiology2019，16，6： | 3 |
| 3 | Association of nonalcoholic fatty liver disease with insulin resistance显示文摘 | Giulio Marchesini Mara Brizi Antonio M Morselli-Labate Giampaolo Bianchi Elisabetta Bugianesi Arthur J McCullough Gabriele Forlani Nazario Melchionda | 1999 | The American Journal of Medicine1999，，5： | 2 |
| 4 | Effects of habitat and landscape fragmentation on humans and hiodiversity in densely populated landscapes显示文摘 | Giulio M D Holderegger R Tobias S | 2009 | Journal o( Environmental Mmagement2009，90，10： | 1 |
| 5 | Sexual andclean- ing behavior and related morphology in the genus cer ocoma(Coleoptera: Meloidae) 显示文摘 | Bologna M A Tureo F Giulio A D | 2003 | Journal of Insect Behovior2003，16，2： | 1 |
| 6 | Extracellular DNA in Heli- cobacter pylori biofilm : a backstairs rumour 显示文摘 | Grande R Di Giulio M Bessa LJ | 2011 | J Appl Microbiol2011，110，2： | 1 |
| 7 | Complexity and coherency: integrating information in the brain 显示文摘 | Giulio Tononi Gerald M Edelman Olaf Spores | 1998 | Trends in Cognitive Sciences (S1364-6613)1998，12，2： | 1 |
| 8 | The effect of a silver nanoparticle polysaccharide system on streptococcal and saliva-derived biofilms 显示文摘 | Di Giulio M Di Bartolomeo S Di Campli E | 2013 | Int J Mol Sci2013，14，13： | 1 |
| 9 | Quantum computing and information Extraction for dynamical quantum systems显示文摘 | GIULIANO B GIULIO C SIMONE M | 2004 | Quantum Information Processing2004，3，10： | 1 |
| 10 | Growth and characterization of tin oxide thin films prepared by reactive sputtering 显示文摘 | Giulio M D Manno D Micocci G | 1993 | Solar Energy Mater Solar Cell1993，31，2： | 1 |
| 11 | Biochemical evidence that tire atypical antipsychotic drags dozapine and rispenlone block 5-HT (2C) receptors in vivo显示文摘 | Di Matteo V Cacchio M Di Giulio C | 2002 | Phannacol Biochem Behav2002，71，4： | 1 |
| 12 | 显示文摘 | Manno D Serra A Di Giulio M | 1997 | J Appl Phys1997，81，6： | 1 |
| 13 | An algo- rithm for finding signals of unknown lengthinDNAse- quences 显示文摘 | GIULIO P GIANCARLO M GRAZIANO P | 2001 | Bioinformatics2001，4，3： | 1 |
| 14 | Systemic administration of insulin-like growth factor decreases motor neuron cell death and promotes muscle reinnervation显示文摘 | Vergani L Giulio AMD Losa M | 1998 | J Neurosci Res1998，54，： | 1 |
| 15 | Oxygen and life span:chronic hypoxia as a model for studying HIF-1 alpha,VEGF and NOS during aging显示文摘 | Giulio CD Bianchi G Cacchio M | 2005 | Respir Physiol Neurobiol2005，147，1： | 1 |
| 16 | Mandibular implant-retained overdenture: finite element analysis of two anchorage sys- tem显示文摘 | Giulio M Massimo L Giulio P | 1998 | Int J Oral Maxillofac Implants1998，13，： | 1 |
| 17 | Cytoglobin and neuroglo- bin in the human brainstem and carotid body显示文摘 | Di Giulio C Zara S De Colli M | 2013 | Adv Exp Med Biol2013，788，： | 1 |
| 18 | Anterior Uveitis Compli- cating Zoledronic Acid Infusion 显示文摘 | Annalisa C Giulio M Elisabetta M | 2009 | Ocular Immunology & Inflam- mation2009，17，： | 1 |
| 19 | Contraction stress of low-shrinkage composite materials assessed with different testing systems显示文摘 | Giulio M Breschi L Antoniolli F | 2010 | DentaIMaterials2010，26，10： | 1 |
| 20 | Anterior Uveitis Compli- cating Zoledronic Acid Infusion 显示文摘 | Annalisa C Giulio M Elisabetta M | 2009 | Ocular Immunology & Inflam- mation2009，17，： | 1 |
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