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| 1 | Role of liver transplantation in the management of hepatoblastoma in the pediatric population显示文摘Hepatoblastoma(HB) is the most common primary liver tumor in children and accounts for two-thirds of all malignant liver neoplasms in the pediatric population. For patients with advanced HB(unresectable or unresponsive to chemotherapy), combined treatment with chemotherapy and liver transplantation is an excellent option. The etiology of HB is mostly obscure because of its extreme rarity although some inherited syndromes and very low birth weight have been associated with it. The prognosis for children with HB has significantly improved in the past three decades thanks to advancements in chemotherapy, surgical resection and postoperative care. In 2002 a surgical staging system called pretreatment extent of disease(PRETEXT) was designed to allow a universal, multidisciplinary approach to patients with HB. Between one-third to two-thirds of patients initially present with unresectable tumors or distant metastases, but up to 85% of these tumors become operable after neoadjuvant chemotherapy. Patients with PRETEXT categories 1, 2, and some 3 are referred for neoadjuvant chemotherapy followed by surgical resection with the goal of complete tumor removal. Classic treatments regimens include a combination of cisplatin, fluorouracil, and vincristine or cisplatin and doxorubicin. Liver transplantation is the only treatment option for unresectable HB. In 2010 the pediatric end-stage liver disease, a pediatric-specific scoring system that determines a patient's ranking on the liver transplant list, began to award additional 'exception' points for patients with HB. We analyzed the Standard Transplant Analysis and Research dataset to assess the impact of changes in exception point criteria for HB on outcomes after liver transplantation at Texas Children's Hospital in Houston, Texas. We found that patients who were listed for transplantation with current HB exception criteria experienced a shorter waitlist time but survival was similar between the two eras. | Saira Khaderi Jacfranz Guiteau Ronald T Cotton Christine O'Mahony Abbas Rana John A Goss | 2014 | World Journal of Transplantation2014，4，4： | 23 |
| 2 | Beyond the Pediatric end-stage liver disease system: Solutions for infants with biliary atresia requiring liver transplant显示文摘Biliary atresia(BA), a chronic progressive cholestatic disease of infants, is the leading cause for liver transplant in children, especially in patients under two years of age. BA can be successfully treated with the Kasai portoenterostomy; however most patients still require a liver transplant, with up to one half of BA children needing a transplant by age two. In the current pediatric end-stage liver disease system, children with BA face the risk of not receiving a liver in a safe and timely manner. In this review, we discuss a number of possible solutions to help these children. We focus on two general approaches:(1) preventing/delaying need for transplantation, by optimizing the success of the Kasai operation; and(2) expediting transplantation when needed, by performing techniques other than the standard deceased-donor, whole, ABO-matched organ transplant. | Mary Elizabeth M Tessier Sanjiv Harpavat Ross W Shepherd Girish S Hiremath Mary L Brandt Amy Fisher John A Goss | 2014 | World Journal of Gastroenterology2014，20，32： | 14 |
| 3 | 24h动态血压监测预测和评估经皮经导管射频消融去肾交感神经术的降压作用显示文摘经皮经导管射频消融去肾交感神经术治疗难治性高血压(renal denervation for resistant hypertension,DENERHTN)临床试验显示,明确诊断的难治性高血压患者经英国指南推荐的标准化阶梯降压治疗(standardized stepped-care antihypertensive treatment,SSAHT)加上使用Symplicity导管的经皮经导管射频消融去肾交感神经术(renal denervation,RDN)。 | Gosse P Cremer A Pereira H Bobrie G Chatellier G Chamontin B Courand P Delsart P Denolle T Dourmap C 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，4： | 6 |
| 4 | Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver显示文摘AIM:To determine if blockade of P-selectin in the isolated blood-perfused cold ex vivo rat liver model protects the liver from ischemia-reperfusion injury. METHODS:The effect of P-selectin blockade was assessed by employing an isolated blood-perfused cold ex vivo rat liver with or without P-selectin antibody treatment before and after 6 h of cold storage in University of Wisconsin solution. RESULTS:In our isolated blood-perfused rat liver model,pre-treatment with P-selectin antibody failed to protect the liver from ischemia-reperfusion injury,as judged by the elevated aspartate aminotransferase activity. In addition,P-selectin antibody treatment did not significantly reduced hepatic polymorphonuclear leukocyte accumulation after 120 min of perfusion. Histological evaluation of liver sections obtained at 120 min of perfusion showed significant oncotic necrosis in liver sections of both ischemic control and P-selectin antibody-treated groups. However,total bile production after 120 min of perfusion was signifi cantly greater in P-selectin antibody-treated livers,compared to control livers. No signifi cant difference in P-selectin and ICAM-1 mRNAs and proteins,GSH,GSSG,and nuclear NF-κB was found between control and P-selectin antibody-treated livers. CONCLUSION:In conclusion,we have shown that blockade of P-selectin alone failed to reduced polymorphonuclear leukocyte accumulation in the liver and protect hepatocytes from ischemia-reperfusion injury in the isolated blood-perfused cold-ex vivo rat liver model. | Samuel Wyllie Neal R Barshes Saul J Karpen John A Goss | 2008 | World Journal of Gastroenterology2008，14，44： | 4 |
| 5 | Characteristics of early unpleasantdental experiences 显示文摘 | Liddell A Gosse V | 1998 | J BehavTherExp Psychiatry1998，29，3： | 1 |
| 6 | The Impact of Corporate Social Responsibility on the Cost of Bank Loans显示文摘 | GOSS A ROBERTS G | 2011 | Journal of Banking and Finance2011，35，7： | 1 |
| 7 | Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induceddegeneration显示文摘 | Mata M Goss J | 2001 | Exp Neurol2001，169，： | 1 |
| 8 | Threat Perception in Product Harm Crises:Do Older Consumers Feel More Vulnerable?显示文摘 | Silvera D H Meyer T Laufer D Goss R J Arsena A R | 2010 | Advances in Consumer Research2010，37，： | 1 |
| 9 | Orthotopic liver transplantation for primary sclerosing chlolangitis:a 12-year single experience显示文摘 | Goss J A Shackleton C R Farmer D G | 1997 | Ann Surg1997，225，： | 1 |
| 10 | Phosphorylation states of translational initiation factors affect mRNA cap binding in wheat显示文摘 | Khan M A Goss D J | 2004 | Biochemistry2004，43，28： | 1 |
| 11 | Tranexamic acid mouthwash-a prospec- tive randomized study of a 2-day regimen vs 5-day regi- men to prevent postoperative bleeding in anticoagulated patients requiring dental extractions显示文摘 | Carter G Goss A | 2003 | Int J Oral Maxillo- fac Surg2003，32，5： | 1 |
| 12 | Selective overexpression of excitatory amino acid transporter 2 (EAAT2) in astrocytes enhances neuroprotection from moderate but not severe hypoxiaischemia显示文摘 | Weller ML Stone IM Goss A | | 0，，： | 1 |
| 13 | Addressing the difficulties in using inductive methods to evaluating human body composition显示文摘 | Peyton A J Mackin R Goss D | 2003 | Biometrie Humaine at Anthropologie2003，21，： | 1 |
| 14 | The impact of corporate social responsibility on the cost of bank loans 显示文摘 | Goss A Roberts G | 2011 | Journal of Banking and Fi- nance2011，35，： | 1 |
| 15 | Selective overexpres- sion o{ excitatory amino acid transporter 2 (EAAT2) in astrocytes enhances neuroprotection {rom moderate but not severe hypoxia-ischemia显示文摘 | Weller ML Stone IM Goss A | 2008 | Neuroscience2008，155，4： | 1 |
| 16 | Prognostic value of the extent of left ventricular hypertrophy and its evolution in the hy- pertensive patient 显示文摘 | Gosse P Cremer A Vircoulon M | 2012 | J Hypertens2012，30，12： | 1 |
| 17 | Clinical review:exogenous surfactant therapy for acute lung injury/acute respiratory distress syndrome--where do we go from here显示文摘 | Dushianthan A Cusack R Goss V | 2012 | Crit Care2012，16，6： | 1 |
| 18 | Inhibition of carbohydrate processing:A new class of anticancer agent显示文摘 | Goss P E Baker M A Carver J P | 1995 | Clin Cancer Res1995，1，9： | 1 |
| 19 | Arsenic as an endocrine disruptor: effects of arsenic on estrogen receptor-mediated gene expression in vivo and in cell culture显示文摘 | DAVEY J C BODWELL J E GOSSE J A | 2007 | Toxicol Sci2007，98，： | 1 |
| 20 | the Value of Sandplay as a Therapeutic Tool for School Guidance Counsellors 显示文摘 | Sarah Goss Marilyn A Campbell | 2004 | Australian Journal of Guidance and Counselling2004，14，： | 1 |
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