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175篇 您的检索式：作者名="GRACE W"

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	题名	作者	年代	出处	被引量
1	Therapeutic potential of targeting the renin angiotensin system in portal hypertension显示文摘Portal hypertension is responsible for the bulk of the morbidity and mortality in patients with cirrhosis.Drug therapy to reduce portal pressure involves targeting two vascular beds.The first approach is to reduce intra hepatic vascular tone induced by the activity of powerful vasocontrictors such as angiotensin Ⅱ,endothelin-1 and the sympathetic system and mediated via contraction of perisinusoidal myofibroblasts and pervascular smooth muscle cells.The second approach is to reduce mesenteric and portal blood flow.Non-selective b-blockers are widely used and have been shown to prolong patient survival and reduce oesophageal variceal bleeding in advanced cirrhosis.However many patients are unable to tolerate these drugs and they are ineffective in a significant proportion of patients.Unfortunately there are no other drug therapies that have proven efficacy in the treatment of portal hypertension and prevention of variceal bleeding.This review briefly outlines current therapeutic approaches to themanagement of portal hypertension,and the evidence supporting the role of the renin angiotensin system(RAS) and the use of RAS blockers in this condition.It will also outline recent advances in RAS research that could lead to the development of new treatments focusing in particular on the recently discovered 'alternate axis' of the RAS.	Chandana B Herath Josephine A Grace Peter W Angus	2013	World Journal of Gastrointestinal Pathophysiology2013，4，1：	9
2	Sulfation and Reaction Characteristics of Nine limestones显示文摘	Maursen K Duo W Grace J R	1999	Fuel1999，79，2：	2
3	Hepatopulmonary syndrome: Update on recent advances in pathophysiology, investigation, and treatment显示文摘	Josephine A Grace Peter W Angus	2013	J Gastroenterol Hepatol2013，，2：	2
4	The effect of cop- per and cadmium on 65 - zinc absorption in zinc - defi- cient and zinc supplemented rats 显示文摘	Evans G W Grace C I and Hahn C	1974	Bioinorg Chem1974，3，11：	1
5	Influence of nitrogen fertiliser application and timing on greenhouse gas emissions from a lychee (Litchi chinensis)orchard in humid subtropical Australia显示文摘	Rowlings D W Grace P R Scheer C et d	2013	Agr Ecosyst Environ2013，179，1：	1
6	Post imaging temporomandibular joint space analysis显示文摘	Kamelchuk L S Grace M G A Major P W	1996	J Craniomandibular Pract1996，14，：	1
7	Generalized cross-validation as a method for choosing agood Ridge parameter显示文摘	GOLUB G H MICHAEL H GRACE W	1979	Technometrocs1979，21，2：	1
8	Strengthening of concrete beams using innovative ductile fiber-reinforced polymer fabric显示文摘	Grace N F George A S Ragheb W F	2002	ACI Struct J2002，99，5：	1
9	Targeting tumor metastasis by regulating Nm23 gene expression 显示文摘	Prabhu W Siddikuzzaman Grace VM	2012	Asian Pac J Cancer Prev2012，13，8：	1
10	Radiation exposure assessment using cytological and molecular biomarkers 显示文摘	Blakely W F Prasarma P G Grace M B	2001	Radiat Prot Dosimetry2001，97，1：	1
11	Oxidation of volatile organic compounds by negative air ions 显示文摘	WU Chih Cheng L EE Grace W M	2004	Atmospheric Environment2004，38，62：	1
12	Hydrodynamics of spout-fluid beds 显示文摘	Sutanto W Epstein N Grace J R	1985	Powder Technology1985，44，2：	1
13	Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats 显示文摘	Teng N L Yong Y H Grace W	1993	Stroke1993，24，1：	1
14	Psychometric analysis of the short - form UCLA Loneliness Scale (ULS-8) in Taiwanese un-dergraduate students 显示文摘	Chia - huei W &Grace Y	2008	Personality and Individual Differences2008，44，：	1
15	Spatial regu- lation of human mesenehymal stem cell differentiation in engineeredosteo-chondral constructs :effects of pre-differentiation,soluble factors and medium perfusion显示文摘	Grayson W L Bhumlratana S Grace Chao P H	2010	Osteoarthritis Cartilage2010，18，5：	1
16	Synergy between conventional phosphorus fire retardants and organically-modified clays can lead to the fire retardancy of styrenics显示文摘	Grace C Charles A W	2003	Polymer Degradation and Stability2003，80，：	1
17	Generalized Cross-Validation as a method for choosing a good ridge parameter显示文摘	GOLUB G H MICHAEL H GRACE W	1979	Technometrocs1979，21，2：	1
18	Real-time quantitative RT-PCR assay of GADD45 gene expression changes as a biomarker for radiation biodosimetry显示文摘	Grace M B Mcleland C B Blakely W F	2002	Int J Radiat Biol2002，7，11：	1
19	Prospects for the biological control of subterranean termites ( Isoptera Rhinotermitidae ), with special reference to Coptotermes formosanus显示文摘	Culliney T W Grace J K	2000	Bulletin of entomological research2000，90，1：	1
20	Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats显示文摘	Yong YH Grace W	1993	Stroke1993，24，：	1

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