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| 1 | ApoB-100, ApoE and CYP7A1 gene polymorphisms in Mexican patients with cholesterol gallstone disease显示文摘AIM: To determine the possible association of the ApoB100 (Xba Ⅰ ), ApoE (Hha Ⅰ ) and CYP7A1 (Bsa Ⅰ ) gene polymorphisms, with the development of cholesterol gallstone disease (GD) in a Mexican population. METHODS: The polymorphisms were analyzed by polymerase chain reaction followed by restriction fragment length polymorphism, in two groups matched by ethnicity, age and sex: patients with GD (n = 101) and stone-free control subjects (n = 101). RESULTS: Allelic frequencies in patients and controls were: 34.16% vs 41.58% (P = 0.124) for X+of ApoB-100; 4.46% vs 5.94% (P = 0.501) for E2, 85.64% vs 78.22% (P = 0.052) for E3, 9.90% vs 15.84% (P = 0.075) for E4 of ApoE; and 25.74% vs 27.72% (P = 0.653) for C of CYP7A1. Differences in genotypic frequencies between the studied groups were not significant (P < 0.05). CONCLUSION: These results demonstrated that no association exists between the studied polymorphisms and cholelithiasis in this high prevalent population. | Sánchez-Cuén Jaime Aguilar-Medina Maribel Arámbula-Meraz Eliakym Romero-Navarro José Granados Julio Sicairos-Medina Laura Ramos-Payán Rosalío | 2010 | World Journal of Gastroenterology2010，16，37： | 14 |
| 2 | Biliary cystadenoma显示文摘The diagnosis of cystadenoma is rare, even more so when located in the extrahepatic bile duct.Unspeciflc clinical signs may lead this pathology to be misdiagnosed.The need for pathological anatomy in order to distinguish cystadenomas from simple biliary cysts is crucial.The most usual treatment nowadays is resection of the bile duct, together with cholecystectomy and Roux-en-Y reconstruction. | Miguel A Hernandez Bartolome Sagrario Fuerte Ruiz Israel Manzanedo Romero Beatriz Ramos Lojo Ignacio Rodriguez Prieto Luis Gimenez Alvira Rosario Granados Carreo Manuel Limones Esteban | 2009 | World Journal of Gastroenterology2009，15，28： | 4 |
| 3 | Role of the HLA-DQ locus in the development of chronic gastritis and gastric carcinoma in Mexican patients显示文摘AIM: To determine the HLA-DQ locus in Mexican patients with Chronic gastritis and gastric adenocarcinoma. METHODS: Oligotyping for HLA-DQ locus was performed in 45 Mexican patients with chronic gastritis and 13 Mexican patients with diffuse-type gastric adenocarcinoma, and was then compared with 99 clinically healthy unrelated individuals. H pylori infection and CagA status were assessed in patients by enzyme-linked immunosor-bent assay (ELISA) method. RESULTS: We found a significant increased frequency of HLA-DQB1*0401 allele in H pylori-positive patients with chronic gastritis when compared with healthy subjects [19 vs 0%, P= 1 × 10-7, odds ratio (OR) = 4.96; 95% confidence interval (95% CI), 3.87-6.35]. We also found a significant increased frequency of HLA-DQB1*0501 in patients with diffuse-type gastric carcinoma in comparison with healthy individuals (P = 1 × 10-6, OR = 13.07; 95% CI, 2.82-85.14). CONCLUSION: HLA-DQ locus may play a different role in the development of H pylori-related chronic gastritis and diffuse-type gastric adenocarcinoma in the Mexican Mestizo population. | Roberto Herrera-Goepfert Jesús K Yamamoto-Furusho Luis F Oate-Ocaa Margarita Camorlinga-Ponce Leopoldo Muoz Jorge A Ruiz-Morales Gilberto Vargas-Alarcón Julio Granados Cellular Biology Section | 2006 | World Journal of Gastroenterology2006，12，48： | 4 |
| 4 | Soy protein regu- lates cholesterol homeostasis through enhanced bile acid svnthesisP显示文摘 | Granados O Torres N Tovar A R | 2007 | Faseb Journal2007，21，5： | 1 |
| 5 | Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and cholesterol transport in the liver and intestine in mice显示文摘 | González-Granillo M Steffensen KR Granados O Torres N Korach-André M Ortíz V Aguilar-Salinas C Jakobsson T Díaz-Villasenor A Loza-Valdes A Hernandez-Pando R Gustafsson JA Tovar AR | | 0，，09： | 1 |
| 6 | 2D shape similarity as a complement for voronoi-delone methods in shape reconstruction显示文摘 | Ruiz O E Cadavid C A Granados M | 2005 | Computers&Graphics2005，29，： | 1 |
| 7 | The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA ( ' Ecstasy' ) 显示文摘 | O'SHEA E GRANADOS R ESTEBAN B | 1998 | Neuropharmacology1998，37，7： | 1 |
| 8 | Frequency of the ETV6-RUNX1, BCR-ABL1, TCF3-PBX1, and MLL-AFF1 fusion genes in Guatemalan pediatric acute lymphoblastic leukemia patients and their ethnic associations显示文摘 | Carranza C Granados L Morales O | 2013 | Cancer Genet2013，206，6： | 1 |
| 9 | A direct HPLC method to estimate streptomycin and its putative ototoxic derivative, streptidine, in blood serum:application to streptomycin-treated humans 显示文摘 | GRANADOS O MEZA G | 2007 | J Pharm Biomed Anal2007，43，2： | 1 |
| 10 | In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA (‘ ecstasy ' ) and p-chloroamphetamine but not the degeneration following fenfluramine显示文摘 | COLADO MI O'SHEA E GRANADOS R | 1997 | Br J Pharmacol1997，121，5： | 1 |
| 11 | Clinical and immunogenetic characterization of Mexican patients with 'rhupus'显示文摘 | SIM(O)N J A GRANADOS J CABIEDES J | 2002 | Lupus2002，11，5： | 1 |
| 12 | In vivo evidence for free radical involvement in the degeneration of rat brain 5 - HT following administration of MDMA ( ' ecstasy' ) and p - chloroamphetamine but not the degeneration following fenfluramine显示文摘 | Colado MI O' Shea E Granados R | 1997 | Br J Pharmacol1997，121，5： | 1 |
| 13 | A direct HPLC method to estimate streptomycin and its putative ototoxic derivative,streptidine,in blood serum:Application to streptom-ycin treated humans显示文摘 | Granados O Meza G | 2007 | Journal of Pharma-ceutical and Biomedica[Analysis2007，43，2： | 1 |
| 14 | Reactivation of a commemial diesel oxidation catalyst by acid washing显示文摘 | Galisteo F C Mariscal R Granados M L Fierro J L Brettes P Salas O | | 0，，10： | 1 |
| 15 | Soy protein isoflavones differentially regulate liver X receptor isoforms to modulate lipid metabolism and choles- terol transport in the liver and intestine in mice显示文摘 | GONZALEZ -GRANILLO M STEFFENSEN KR GRANADOS O | 2012 | Diabeto- Iogia2012，55，9： | 1 |
| 16 | D1 but not D5 dopamine receptors are critical for LTP,spatial learning,and LTP-Induced arc and zif268 expression in the hippocampus显示文摘 | Granado N Ortiz O Suarez LM | 2008 | Cereb Cortex2008，18，1： | 1 |
| 17 | 显示文摘 | Moreno N O Garcia A | 1998 | Phys Rev B1998，58，11： | 1 |
| 18 | A Direct HPLC Method to Estimate Streptomycin and Its Putative Ototoxic Derivative, Streptidine, in Blood Serum: Application to Streptomycin-Treated Humans 显示文摘 | GRANADOS O MEZA G | 2007 | Pharm Biomed Anal2007，43，： | 1 |
| 19 | Frequency of the ETV6-RUNX1,BCR/ABL,TCF-PBX1,and MLL-AFF1fusion genes in Guatemalan pediatric acute lymphoblastic leukemia patients and their ethnic associatons显示文摘 | Carranza C Granados L Morales O | | 0，，06： | 1 |
| 20 | Degradation of atrazine using metalloporphyrins supported on TiO2 under visible light irradiation显示文摘 | Granados O G P E A Ortega F M | 2009 | Applied Catalysis B:Environmental2009，89，34： | 1 |
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