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1146篇 您的检索式:作者名="GREENES R A"
    题名 作者 年代 出处 被引量
1Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency显示文摘Pluripotency,一个细胞的能力区分并且产生所有胚胎的系,定义象胚胎的茎(ES ) 那样的哺乳动物的细胞类型的一个小数字细胞。当它通常被保持了时,那 pluripotency 是 transcriptional 的产品激活并且维持关键干细胞基因的表达式的规章的网络,积累的证据在建立并且保卫 ES 房间的 pluripotency 为 epigenetic 进程正在指向一个关键角色,象维持区分的房间类型的身份一样。以便更好在 pluripotency 理解 epigenetic 机制的角色,我们检验了在经历区别进一个 mesendodermal 系的人的 ES 房间(hESCs ) 染色体宽的染色质修正的动力学。我们发现在倡导者的染色质修正在区别期间仍然保持大部分不变,除了在在在 H3K27 的 acetylation 和 methylation 之间的一个动态开关标记在基因表示的激活和 silencing 之间的转变的倡导者的一个小数字,建议在在大多数差别上的房间命运承诺的一个层次表示了基因。我们也在 50 000 潜在的 enhancers 上印射,并且在染色质修正,特别 H3K4me1 和 H3K27ac 观察了大得多的动力学,它与他们的潜在的目标基因的表示相关。这些 enhancers 的进一步的分析揭示了 pluripotency 和可以在 hESCs 授与发展胜任的一个平衡状态的一口染色质签名陈述语气的潜在地关键的 transcriptional 管理者。我们的结果提供在定义 enhancers 和 pluripotency 支持染色质修正的角色的新证据。R David Hawkins Gary C Hon Chuhu Yang Jessica E Antosiewicz-Bourget Leonard K Lee Que-Minh Ngo Sarit Klugman Keith A Ching Lee E Edsall Zhen Ye Samantha Kuan Pengzhi Yu Hui Liu Xinmin Zhang Roland D Green Victor V Lobanenkov Ron Stewart James A Thomson Bing Ren 2011Cell Research2011,21,10:6
2Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘E Joanna Baxter Linda M Scott Peter J Campbell Clare East Nasios Fourouclas Soheila Swanton George S Vassiliou Anthony J Bench Elaine M Boyd Natasha Curtin Mike A Scott Wendy N Erber Anthony R Green 2005The Lancet . 2005 (9464)2005,,:2
3Electronic transducers for industrial measurement of low value capacitance显示文摘S M Huang A L Stott R G Green 1988Journal Physics Engineering Science Instrument1988,21,3:2
4脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义,MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue 2010中华物理医学与康复杂志2010,32,4:2
5Mechanisms of Disease: the Myeloprolife Rative Disorders显示文摘Campbell P J Green A R 2006N Engl J Med2006,355,:1
6Comparative DNA sequence analysis of wheat and rice genomes显示文摘 La Rota M Bermudez-Kandianis C E Greene R A Kantety R 2003Genome Res2003,13,:1
7Interactions of tea tannins and condensed tannins with proteins显示文摘Frazier R A Deaville E R Green R J 2010Journal of Pharmaceutical and Biomedical Analysis2010,51,:1
8Early analgesia for children with acute abdam inal pain 显示文摘Green R Bulloch B Kabani A 2005Pediatrics2005,116,4:1
9Prognostic markers in triple-negative breast cancer显示文摘Rakha E A E1-Sayed M E Green A R 2007Cancer2007,109,1:1
10Wound-induced proteinase inhibitor in plant leaves:a possible defense mechanism against insects显示文摘GREEN T R RYAN C A 1972Science1972,175,:1
11Identification of novel Smad binding proteins 显示文摘Warner D R Roberts E A Greene R M 2003Biochem Biophys Res Commun2003,312,4:1
12Buried contact silicon solar cells显示文摘Wenham S R Honsberg C R Green M A 1994Solar Energy Matrials and Solar Cells1994,34,:1
13Prognostic markers in triple-negative breast cancer显示文摘Rakha E A EL-Sayed M E Green A R 2007Cancer2007,109,:1
14Prognostic markers in triple-negative breast cancer显示文摘Rakha E A EI-Sayed M E Green A R 2007Cancer2007,109,:1
15Response and modeling of cantilever retaining walls subjected to seismic motions显示文摘GREEN R A OLGUN C G CAMERON W I 2008Computer-Aided Civil and Infrastructure Engineering2008,23,4:1
16Children' s cooperative and competitive interactions in limited resource situations:A literature review显示文摘Green V A Rechis R 0,,:1
17Immunogenic and tolerogenic cell death显示文摘Green D R Ferguson T Zitvogel L A 2009Nat Rev Immunol2009,9,5:1
18The Tobacco Chemists' Research Conference: a half century forum for advances in analytical methodology of tobacco and its products显示文摘GREEN C R RODGMAN A 1996Recent Advances in Tobacco Science1996,22,13:1
19Prestressed FRP sheets for poststrengthening reinforced concrete beams 显示文摘Wight R G Green M F Erki M A 2001Journal of Composites for Construction2001,5,4:1
20Prestressed FRP sheets for poststrengthening reinforced concrete beams 显示文摘Wight R G Green M F Erki M A 2001Journal of Composites for Construction2001,5,4:1
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