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| 1 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 2 | Prospective evaluation of the short access cholangioscopy for stone clearance and evaluation of indeterminate strictures显示文摘BACKGROUND: Peroral cholangioscopy facilitates diagnosis and therapy of biliary disorders. This study prospectively evaluated a new short access cholangioscopy. METHODS: Consecutive patients were included as follows: difficult stones(group 1) underwent cholangioscopy with electrohydraulic lithotripsy and indeterminate biliary strictures(group 2) were evaluated with macroscopic assessment and cholangioscopy guided biopsy sampling. We evaluated the complete stone clearance rate(group 1) and diagnostic accuracy(group 2). Follow-up was performed over a median of 13 and 16 months, respectively.RESULTS: Group 1(n=21): complete stone clearance defined as lack of stones in cholangiography and stone removal during cholangioscopy was achieved in 15(71.4%) patients. Clinical stone clearance defined as lack of symptoms, laboratory abnormalities and hospital visits during follow-up, irrespective of stone clearance was evident in 17(81.0%) patients. One serious adverse event occurred(bile duct perforation). Group 2(n=28): malignancy was confirmed in 15 patients. Sensitivity, specificity and diagnostic accuracy of cholangioscopy were 85.7%, 75.0% and 80.7%, respectively. Sensitivity, specificity and diagnostic accuracy of biopsies were 54.5%, 100.0% and 72.2%, respectively. No serious adverse events occurred, and one patient was lost to follow-up.CONCLUSIONS: The novel system enabled complex stone treatment and biliary stricture diagnosis. Cholangioscopy outperformed direct biopsy regarding characterization of indeterminate strictures. | Athanasios D Sioulas Muhammad A El-Masry Stefan Groth Guido Schachschal Mario Anders Thomas Rosch Ulrike Denzer | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，1： | 2 |
| 3 | Efficiency and toxicity of liposome-mediated gene transfer to corneal endothelial cells显示文摘 | Pleyer U Groth D Hinz B Keil O Bertelmann E Rieck P | 2002 | Exp Eye Res2002，73，1： | 1 |
| 4 | Chemotherapy in advanced gastric cancer: asystematic review and meta-analysis basedon aggregate data显示文摘 | WAGNER A D GROTHE W HAERTING J | 2006 | J Clin Oncol2006，24，18： | 1 |
| 5 | Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data 显示文摘 | Wagner A D Grothe W Haerting J | 2006 | J Clin Onco2006，24，18： | 1 |
| 6 | Chemotherapy in advanced gastric cancer: a systematic review and meta analysis based on aggregate data显示文摘 | WAGNER A D GROTHE W HAERTING J | 2006 | J Clin Oncol2006，24，： | 1 |
| 7 | Sheath-blight resistance QTLs in japonica rice germplasm 显示文摘 | Nelson J C Oard J H Groth D E | 2012 | Euphyti- ca2012，184，1： | 1 |
| 8 | 查看详情显示文摘 | Bellinger K C G Kempner E Groth D F | | 0，，： | 1 |
| 9 | Chemotherapy in advanced gastric cancer: A systematic review and meta analysis based on aggregate data显示文摘 | Wagner A D Grothe W Haerting J | 2006 | Journal of Clinical Oncology2006，24，18： | 1 |
| 10 | The altmetrics collec- tion显示文摘 | Priem J Groth P Taraborelli D | 2012 | PLoS ONE2012，7，48： | 1 |
| 11 | Management of cervical esophageal injury after spinal surgery显示文摘 | Rueth N Shaw D Groth S | 2010 | Ann Thorac Surg2010，90，4： | 1 |
| 12 | Treatment of pain syndromes with venlafaxine显示文摘 | GROTHE D R SCHECKNER B ALBANO D | 2004 | Pharmacotherapy2004，24，5： | 1 |
| 13 | The role of ADAM-mediated shedding in vascular biology 显示文摘 | Dreymueller D Pruessmeyer J Groth E | 2012 | Eur J Cell Biol2012，91，67： | 1 |
| 14 | Genetic evidence for mixed parentage in nests of the emu ( Dromaius novaehollandiae) 显示文摘 | Taylor EL Blache D Groth D | 2000 | Behay Ecol Sociobiol2000，47，： | 1 |
| 15 | Treatment of pain syndrome with venlafaxine显示文摘 | Grothe DR Scheckner B Albano D | 2004 | Pharmacotherapy2004，24，5： | 1 |
| 16 | Facial rejuvenation with SMASectomy and FAME using vertical vector显示文摘 | GRAF R GROTH A K PACE D et at | 2008 | Aesthetic Plast Surg2008，32，4： | 1 |
| 17 | N eurotrophin activation of NFAT - dependent transcription contributes to the regulation of pro - nociceptive genes 显示文摘 | Groth R D Coicou L G Mermelstein P G | 2007 | J N eurochem2007，102，4： | 1 |
| 18 | Attempts to restore scrapie prion infectivity after exposure to protein denaturants显示文摘 | Prusiner SB Groth D Serban A | 1993 | Proc Natl Acad Sci USA1993，90，： | 1 |
| 19 | Effects of grassland plant species diversity,abundance,and composition on foliar fun- gal disease显示文摘 | Mitchell C E Tilman D Groth J V | 2002 | Ecology2002，83，6： | 1 |
| 20 | Structure of the recombinant full-length hamster prion protein PrP(29-231) : the N terminus is highly flexible 显示文摘 | Donne DG Viles JH Groth D | 1997 | Proc Natl Acad Sci USA1997，94，13： | 1 |
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