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| 1 | Metabolic syndrome as a risk factor for gallstone disease显示文摘AIM: To establish an association between the presence of metabolic syndrome and the development of gallstone disease.METHOIDS: We carried out a cross-sectional study in a check-up unit in a university hospital in Mexico City. We enrolled 245 subjects, comprising 65 subjects with gallstones (36 women, 29 men) and 180 controls (79women and 101 men without gallstones). Body mass index, waist circumference, blood pressure, plasma insulin, and serum lipids and lipoproteins levels were measured. Insulin resistance was calculated by homeostasis model assessment. Unconditional logistic regressionanalysis (univariate and multivariate) was used to calculate the risk of gallstone disease associated with the presence of at least three of the criteria (Adult Treatment Panel Ⅲ). Analyses were adjusted for age and sex.RESULTS: Among 245 subjects, metabolic syndrome was present in 40% of gallstone disease subjects, compared with 17.2% of the controls, adjusted by age and gender (odds ratio (OR) = 2.79; 95%CI, 1.46-5.33; P = 0.002),a dose-dependent effect was observed with each component of metabolic syndrome (OR = 2.36, 95%CI, 0.72-7.71;P = 0.16 with one component and OR = 5.54, 95%CI,1.35-22.74; P = 0.02 with four components of metabolic syndrome). Homeostasis model assessment was significantly associated with gallstone disease (adjusted OR = 2.25;95%CI, 1.08-4.69; P = 0.03).CONCLUSION: We conclude that as for cardiovascular disease and diabetes mellitus, gallstone disease appears to be strongly associated with metabolic syndrome. | Nahum Méndez-Sánchez Norberto C. Chavez-Tapia Daniel Motola-Kuba Karla Sanchez-Lara Guadalupe Ponciano-Rodríguez Héctor Baptista Martha H. Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，11： | 32 |
| 2 | Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects显示文摘AIM: To establish an association between the serum leptin levels and the development of gallstone disease (GD).METHODS: We carried out a non-matched case-controlled study in a university hospital in Mexico City. Two hundred and eighty-seven subjects were included: 97 cases with gallstones and 190 controls. Body mass index (BMI), fasting plasma leptin, insulin, serum lipid, and lipoprotein levels were measured. Insulin resistance was calculated by homeostasis model assessment (HOMA-IR). Unconditional logistic regression analysis (univariate and multivariate)stratified by BMI was used to calculate the risk of GD.RESULTS: The multivariate conditional regression analysis revealed a model for those patients with BMI <30. The selected variables in the model were HOMA-IR index with OR = 1.31, P= 0.02 and leptin higher than median with OR = 2.11, P= 0.05. In the stratum of BMI ≥30, we did not find a useful model.CONCLUSION: We concluded that insulin resistance and the development of GD appears to be associated with serum leptin levels in subjects with overweight, but not in obese subjects with similar metabolic profiles. | Nahum Méndez-Sánchez Luisa B Bermejo-Martínez Yolanda Vi(n|~)als Norberto C Chavez-Tapia Irina Vander Graff Guadalupe Ponciano-Rodríguez Martha H Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，39： | 11 |
| 3 | National natural capital accounting with the ecological footprint concept显示文摘 | Mathis Wackernagel Larry Onisto Patricia Bello Alejandro Callejas Linares Ina Susana López Falfán Jesus Méndez Garc??a Ana Isabel Suárez Guerrero Ma Guadalupe Suárez Guerrero | 1999 | Ecological Economics1999，，3： | 5 |
| 4 | Pathological features and diagnosis of intraductal papillary mucinous neoplasm of the pancreas显示文摘Intraductal papillary mucinous neoplasm(IPMN) of the pancreas is a noninvasive epithelial neoplasm of mucinproducing cells arising in the main duct(MD) and/or branch ducts(BD) of the pancreas.Involved ducts are dilated and filled with neoplastic papillae and mucus in variable intensity.IPMN lacks ovarian-type stroma,unlike mucinous cystic neoplasm,and is defined as a grossly visible entity(≥ 5 mm),unlike pancreatic intraepithelial neoplasm.With the use of high-resolution imaging techniques,very small IPMNs are increasingly being identified.Most IPMNs are solitary and located in the pancreatic head,although 20%-40% are multifocal.Macroscopic classification in MD type,BD type and mixed or combined type reflects biological differences with important prognostic and preoperative clinical management implications.Based on cytoarchitectural atypia,IPMN is classified into low-grade,intermediategrade and high-grade dysplasia.Based on histological features and mucin(MUC) immunophenotype,IPMNs are classified into gastric,intestinal,pancreatobiliary and oncocytic types.These different phenotypes can be observed together,with the IPMN classified according to the predominant type.Two pathways have been suggested:gastric phenotype corresponds to less aggressive uncommitted cells(MUC1-,MUC2-,MUC5 AC +,MUC6 +) with the capacity to evolve to intestinal phenotype(intestinal pathway)(MUC1-,MUC2 +,MUC5 AC +,MUC6- or weak +) or pancreatobiliary /oncocytic phenotypes(pyloropancreatic pathway)(MUC1 +,MUC 2-,MUC5 AC +,MUC 6 +) becoming more aggressive.Prognosis of IPMN is excellent but critically worsens when invasive carcinoma arises(about 40% of IPMNs),except in some cases of minimal invasion.The clinical challenge is to establish which IPMNs should be removed because of their higher risk of developing invasive cancer.Once resected,they must be extensively sampled or,much better,submitted in its entirety for microscopic study to completely rule out associated invasive carcinoma. | Víctor M Castellano-Megías Carolina Ibarrola-de Andrés Guadalupe López-Alonso Francisco Colina-Ruizdelgado | 2014 | World Journal of Gastrointestinal Oncology2014，6，9： | 4 |
| 5 | National natural capital accounting with the ecological footprint concept显示文摘 | Mathis Wackernagel Larry Onisto Patricia Bello Alejandro Callejas Linares Ina Susana López Falfán Jesus Méndez Garc??a Ana Isabel Suárez Guerrero Ma Guadalupe Suárez Guerrero | 1999 | Ecological Economics1999，，3： | 3 |
| 6 | Hepatitis C virus core protein expression leads to biphasic regulation of the p21 cdk inhibitor and modulation of hepatocyte cell cycle显示文摘 | Nguyen H Mudryj M Guadalupe M | 2003 | Virology2003，312，1： | 1 |
| 7 | Hepatits C virus core protein expression leads to biphasic regulation of the p21 cdk inhibitor and modulation of hepatocyte cell cycle 显示文摘 | Nguyen H Mudryj M Guadalupe M | 2003 | Virology2003，312，1： | 1 |
| 8 | Differentialsynthesis of fermentative aroma compounds of two related commercialwine yeast strains显示文摘 | MOLINA A M GUADALUPE V VARELA C | 2009 | Food Chemistry2009，117，2： | 1 |
| 9 | Use of chitosan-based edible coatings in combination with other natural compounds, to control Rhizopus stolonifer and Escherichia coli DH5α in fresh tomatoes显示文摘 | Margarita Ramos-García Elsa Bosquez-Molina Jesús Hernández-Romano Guadalupe Zavala-Padilla Eduardo Terrés-Rojas Irán Alia-Tejacal Laura Barrera-Necha Mónica Hernández-López Silvia Bautista-Ba?os | 2012 | Crop Protection2012，，： | 1 |
| 10 | Preparation of benzylidene barbituric acids promoted by infrared irradiation in absence of solvent显示文摘 | Ruben S Rene M | 2000 | Synth Commun2000，30，7： | 1 |
| 11 | Characterization of sustainable bio-based mortar for con-crete repair显示文摘 | Guadalupe Sierra-Beltran M Jonkers H M Schlangen E | 2014 | Construction and Building Materials2014，67，： | 1 |
| 12 | Executive compensation and competition in the banking and financial sectors显示文摘 | Cu n軌a t V Guadalupe M | | 0，，03： | 1 |
| 13 | A general procedure for the fluorodenitration of aromatic substrates显示文摘 | Maggini M Passudetti M Guadalupe G T | 1991 | The Journal of Organic Chemistry1991，56，22： | 1 |
| 14 | Application of Kalman filtering for continuous real-time tracking of power system harmonics显示文摘 | Saiz V M M Guadalupe J B | 1997 | IEE Proceedings on Generation Transmission and Distribution1997，144，1： | 1 |
| 15 | Viral suppression and immune restoration in the gastrointestinal mucosa of immunodericiency virus type 1-infected patients initiating therapy during primary or chronic infection 显示文摘 | Guadalupe M Sankaran S George MD | 2006 | J virol2006，80，： | 1 |
| 16 | Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency type 1 infection and substantial delay inrestoration following highly active antiretroviral therapy显示文摘 | Guadalupe M Reay E Sankaran S | 2003 | J Virol2003，77，11： | 1 |
| 17 | Viral suppression and immune restoration in the gastrointestinal mucosa of human immunodeficiency virus type 1-infected patients initiating theraoy during primary or chronic infection显示文摘 | Guadalupe M Sankaran S George MD | 2006 | J Virol2006，80，16： | 1 |
| 18 | Inhibition of surgically induced miosis and prevention of postoperative macular edema with nepafenac显示文摘 | Guadalupe C ervantes-Coste Yuriana G S á nchez-Castro M ó nica Orozco-Carroll | 2009 | Clinical Ophthalmology2009，3，： | 1 |
| 19 | Different synthe- sis of fermentative aroma compounds of two related commercial wine yeast strains显示文摘 | MOL1NA A M GUADALUPE V VARELA C | 2009 | Food Chem2009，117，2： | 1 |
| 20 | The effects of cold -pretreatment, auxins and carbon source on anther culture of rice 显示文摘 | GABRIELA TREJO-TAPIA URIEL M A GUADALUPE S M | 2002 | Plant Cell Tissue and Organ Cul- ture2002，71，： | 1 |
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