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| 1 | Toxicity of Multi-Walled Carbon Nanotubes,Graphene Oxide,and Reduced Graphene Oxide to Zebrafish Embryos显示文摘Objective This study was aimed to investigate the toxic effects of 3 nanomaterials, i.e. multi-walled carbon nanotubes(MWCNTs), graphene oxide(GO), and reduced graphene oxide(RGO), on zebrafish embryos. Methods The 2-h post-fertilization(hpf) zebrafish embryos were exposed to MWCNTs, GO, and RGO at different concentrations(1, 5, 10, 50, 100 mg/L) for 96 h. Afterwards, the effects of the 3 nanomateria on spontaneous movement, heart rate, hatching rate, length of larvae, mortality, and malformations ls were evaluated. Results Statistical analysis indicated that RGO significantly inhibited the hatching of zebrafish embryos. Furthermore, RGO and MWCNTs decreased the length of the hatched larvae at 96 hpf. No obvious morphological malformation or mortality was observed in the zebrafish embryos after exposure to the three nanomaterials. Conclusion MWCNTs, GO, and RGO were all toxic to zebrafish embryos to influence embryos hatching and larvae length. Although no obvious morphological malformation and mortality were observed in exposed zebrafish embryos, further studies on the toxicity of the three nanomaterials are still needed. | LIU Xiao Tong MU Xi Yan WU Xiao Li MENG Li Xuan GUAN Wen Bi MA Yong Qiang SUN Hua WANG Cheng Ju LI Xue Feng | 2014 | Biomedical and Environmental Sciences2014，27，9： | 6 |
| 2 | Comprehensive test stand for high-intensity cyclotron development显示文摘A comprehensive test stand for high-intensity cyclotron development,a 10 MeV 430 μA cyclotron,has been successfully constructed at China Institute of Atomic Energy (CIAE) for the experimental verification of the viability of a 100 MeV high-intensity cyclotron (CYCIAE-100) being constructed at CIAE.The verification includes the overall design technology,detail design and engineering technology for the crucial parts of the machine,e.g.main magnet and beam diagnostics.It will also pave the way for future enhancement of the beam intensity.The test stand consists of a H-ion source,axial injection system,central region,main magnet and coil,RF resonator,stripping extraction,and auxiliary systems,which include the RF power amplifier,high voltage and DC power supplies,electric apparatus,beam diagnostics,control,vacuum,water cooling,pneumatic system,and safety interlock.This paper presents the work regarding the design and sub-system development of the test sand,and the results of the beam commissioning of the machine. | ZHANG TianJue LI ZhenGuo CHU ChengJie XING JianSheng GUAN FengPing ZHONG JunQing JI Bin GE Tao YIN ZhiGuo HOU ShiGang PAN GaoFeng YAO HongJuan LU YinLong WANG ZhenHui WU LongCheng LIN Jun JIA XianLu WEI SuMin WEN LiPeng WANG Feng XIA Le CAI HongRu XIE HuaiDong CHEN RongFan ZHANG Yan ZHANG SuPing LIU GengShou ZOU Jian AN ShiZhong YANG JianJun BI YuanJie YANG Fang | 2011 | Chinese Science Bulletin2011，56，3： | 3 |
| 3 | Overexpression of YKL-40 is an independent prognostic marker in gastric cancer显示文摘 | Jiong Bi Sze-Hang Lau Zi-Li Lv Dan Xie Wen Li Ying-Rong Lai Jue-Min Zhong Hui-qun Wu Qiao Su Yu-long He Wen-Hua Zhan Jian-Ming Wen Xin-Yuan Guan | 2009 | Human Pathology2009，，： | 1 |
| 4 | Epidemiological investigation on mercury contamination in gold mining and its effect on health显示文摘In this paper, it is reported the environmental contamination of mercury in gold mining in China and the effect of mercury exposure on health. The results showed that Hg concentration of air in the Hg\|use workshop, the mining area and the population’s living area were 0.058 mg/m 3, 0.047 mg/m 3 and 0.043 mg/m 3, respectively. Hg content of air in the suburbs 5 km from the mining area was 0.007 mg/m 3. The difference in Hg concentration of air was statistically significant ( p <0.05) between the Hg\|use workshop and the population’s living area. But there was no difference between the mining area and the population’s living area ( p >0.05). All of the values determined above were excessed the Chinese national standards. Hg concentration of snowfall and soil in the mining area were 0.058 mg/L and 2.78 μg/g. Both of them differed from those of the living area ( p< 0.01 and p <0.05). Hg content of the waste water was up to the national emission standards. Hg contents of wild plants differed inside as compared to outside the mining area ( p <0.05). But Hg content of plants of the two places was both in the range of the background. The results that Hg levels accumulated in the bodies showed that Hg concentration of hair, blood and urine of the workers of the Hg\|exposed group (group I, GI) were all higher than those of the non\|Hg\|exposed group (group II, GII). Hg in hair and urine was statistically significant ( p<0.001 and p<0.005) between the two groups. Hg content of hair of twenty\|five percent of workers in GI was higher than 4 ppm, and a small number of workers in this group was higher than 10 ppm. The Hg content of urine of eighty percent of workers in GI was higher than that of the Chinese normal human’s standard. Some slight but typical clinical symptoms, of Hg poisoning were found in some worker’s by clinical examination. It proved that the environment of the gold mining area was polluted by Hg vapor in varying degrees. The population was suffering from mild degree of Hg poisoning. It pointed to the fact that protecting the ecosystem and human’s health against Hg pollution should be paid great attention in this gold mining area. | GUAN Ming 1, ZHENG De\|ming 1, YU Ya\|qin 1, ZHAO Jie\|xu 1, BI Wen\|xiang 1, WU Di 1, LING Jing 1, DU Wei 1, XIA Yu\|Yong 1, GAO Shen 2, SUN Wei\|wei 2, GUAN Ci\|nan 3, WANG Yan\|li 3 (1. Norman Bethune University of Medical Sciences, Ch | 2000 | Journal of Environmental Sciences2000，12，S1： | 0 |
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