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| 1 | Three-dimensional artificial transpiration for efficient solar waste-water treatment显示文摘Solar steam generation is emerging as promising solar-energy conversion technology for potential applications in desalination, sterilization and chemical purification. Despite the recent use of photon management and thermal insulation, achieving optimum solar steam efficiency requires simultaneous minimization of radiation, convection and conduction losses without compromising light absorption.Inspired by the natural transpiration process in plants, here we report a 3 D artificial transpiration device with all three components of heat loss and angular dependence of light absorption minimized, which enables over 85% solar steam efficiency under one sun without external optical or thermal management. It is also demonstrated that this artificial transpiration device can provide a complementary path for waste-water treatment with a minimal carbon footprint, recycling valuable heavy metals and producing purified water directly from waste water contaminated with heavy metal ions. | Xiuqiang Li Renxing Lin George Ni Ning Xu Xiaozhen Hu Bin Zhu Guangxin Lv Jinlei Li Shining Zhu Jia Zhu | 2018 | National Science Review2018，5，1： | 27 |
| 2 | MiR-29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6显示文摘Osteosarcoma 是骨头的最普通的主要肉瘤,并且它是在青少年和年轻成年人之中的癌症死亡的一个领先的原因。然而,糟糕位于 osteosarcoma carcinogenesis 遗体下面的分子的机制理解。最近, cyclin 依赖的 kinase (CDK6 ) 6 作为重要 oncogene 被识别。我们发现了那 CDK6 蛋白质水平,而非 CDK6 mRNA 水平,比的在 osteosarcoma 纸巾是高得多的在正常邻近的纸巾,它显示在 osteosarcoma 涉及 CDK6 规定的 post-transcriptional 机制。MiRNAs 是镇压的小非编码的 RNA 在 post-transcriptional 水平的基因表示并且广泛地被显示了在许多人的癌症起重要作用。在这研究,我们用生物信息学方法作为 CDK6 的一个新奇管理者调查了 miR-29b 的角色。我们证明 CDK6 能是由经由到在 osteosarcoma 房间的 3-UTR 区域的绑定的 miR-29b 的 downregulated。而且,我们在 osteosarcoma 纸巾识别了在 miR-29b 和 CDK6 蛋白质层次之间的反的关联。最后,我们在 osteosarcoma 房间检验了 CDK6 表示的 miR-29b-driven 压抑的功能。结果表明 miR-29b 由在增长和移植进程指向 CDK6 充当 osteosarcoma 的肿瘤 suppressor。一起拿,我们的结果在 osteosarcoma 在 CDK6 的规定为 miR-29b 加亮一个重要角色并且可以为未来 osteosarcoma 治疗打开新大街。 | Kegan Zhu Lei Liu Junliang Zhang Yanbo Wang Hongwei Liang Gentao Fan Zhenhuan Jiang Chen-Yu Zhang Xi Chen Guangxin Zhou | 2016 | Protein & Cell2016，7，6： | 18 |
| 3 | Function identification of miR482b, a negative regulator during tomato resistance to Phytophthora infestans显示文摘Tomato is an important horticultural and economic crop cultivated worldwide.As Phytophthora infestans becomes a huge threat to tomato production,it is necessary to study the resistance mechanisms of tomato against P.infestans.Our previous research has found that miR482 might be involved in tomato–P.infestans interaction.In this study,miR482b precursor was cloned from Solanum pimpinellifolium“L3708”and miR482b was shown to decrease in abundance in tomato following P.infestans infection.Compared to wild-type tomato plants,tomato plants that overexpressed miR482b displayed more serious disease symptoms after P.infestans infection,with more necrotic cells,longer lesion diameters,and increased P.infestans abundance.Meanwhile,silencing of miR482b was performed by short tandem target mimic(STTM),resulting in enhancement of tomato resistance to P.infestans.Using miRNA and degradome data sets,NBS–LRR disease-resistance genes targeted by miR482b were validated.Negative correlation between the expression of miR482b and its target genes was found in all miR482b-overexpressing and-silencing tomato plants.Our results provide insight into tomato miR482b involved in the response to P.infestans infection,and demonstrate that miR482b–NBS–LRR is an important component in the network of tomato–P.infestans interaction. | Ning Jiang Jun Meng Jun Cui Guangxin Sun Yushi Luan | 2018 | Horticulture Research2018，5，1： | 13 |
| 4 | Face Image Recognition Based on Convolutional Neural Network显示文摘With the continuous progress of The Times and the development of technology,the rise of network social media has also brought the“explosive”growth of image data.As one of the main ways of People’s Daily communication,image is widely used as a carrier of communication because of its rich content,intuitive and other advantages.Image recognition based on convolution neural network is the first application in the field of image recognition.A series of algorithm operations such as image eigenvalue extraction,recognition and convolution are used to identify and analyze different images.The rapid development of artificial intelligence makes machine learning more and more important in its research field.Use algorithms to learn each piece of data and predict the outcome.This has become an important key to open the door of artificial intelligence.In machine vision,image recognition is the foundation,but how to associate the low-level information in the image with the high-level image semantics becomes the key problem of image recognition.Predecessors have provided many model algorithms,which have laid a solid foundation for the development of artificial intelligence and image recognition.The multi-level information fusion model based on the VGG16 model is an improvement on the fully connected neural network.Different from full connection network,convolutional neural network does not use full connection method in each layer of neurons of neural network,but USES some nodes for connection.Although this method reduces the computation time,due to the fact that the convolutional neural network model will lose some useful feature information in the process of propagation and calculation,this paper improves the model to be a multi-level information fusion of the convolution calculation method,and further recovers the discarded feature information,so as to improve the recognition rate of the image.VGG divides the network into five groups(mimicking the five layers of AlexNet),yet it USES 3*3 filters and combines them as a convolution sequence.Network deeper DCNN,channel number is bigger.The recognition rate of the model was verified by 0RL Face Database,BioID Face Database and CASIA Face Image Database. | Guangxin Lou Hongzhen Shi | 2020 | China Communications2020，17，2： | 10 |
| 5 | Corrosion behavior of an Al-6Mg-Sc-Zr alloy显示文摘The corrosion behavior of an Al-6Mg-Sc-Zr alloy was studied and compared with that of an Al-6Mg-Zr alloy.The addition of scandium into the Al-6Mg-Zr alloy reduced the susceptibility to exfoliation corrosion. By using the constantload tensile method in a 3.5 wt.% NaCl solution, the resistance to SCC of the Al-6Mg-Sc-Zr alloy was higher than that ofthe Al-6Mg-Zr alloy. When the specimens were not applied with an anodic current, the Al-6Mg-Sc-Zr alloy was resistanceto SCC and no brittle cracking was found on the fracture surface. When an anodic current was applied, the Al-6Mg-Sc-Zralloy specimens failed as a result of accelerated corrosion rather than SCC. It was believed that the addition of scandium re-sulted in (Al3Sc, Zr) particles that greatly refined grains and promoted the formation of homogeneous discontinuous distri-bution of β-phase in the alloy base, which much contributed to good corrosion resistance of the Al-6Mg-Sc-Zr alloy. | XU Guangxin TAO Binwu LIU Jianhua LI Songmei | 2005 | Rare Metals2005，24，3： | 8 |
| 6 | Mechanisms underlying attenuation of apoptosis of cortical neurons in the hypoxic brain by flavonoids from the stems and leaves of Scutellaria baicalensis Georgi显示文摘Flavonoids from the stems and leaves of Scutellaria baicalensis Georgi, an antioxidant, markedly improve memory impairments and neuronal injuries. In the present study, primary cortical neurons of rats were exposed to potassium cyanide to establish a model of in vitro neural cell apoptosis. Inhibition of apoptosis by flavonoids from the stems and leaves of Scutellaria baicalensis Georgi at concentrations of 18.98, 37.36, and 75.92 μg/mL was detected using this model. These flavonoids dramatically increased cell survival, inhibited cell apoptosis and excessive production of malondialdehyde, and increased the activities of superoxide dismutase, glutathione peroxidase, and Na+-K+-ATPase in primary cortical neurons exposed to potassium cyanide. The flavonoids from the stems and leaves of Scutellaria baicalensis Georgi were originally found to have a polyhydric structure and to protect against cerebral hypoxia in in vitro and in vivo models, including hypoxia induced by potassium cyanide or cerebral ischemia. The present study suggests that flavonoids from the stems and leaves of Scutellaria baicalensis Georgi exert neuroprotective effects via modulation of oxidative stress, such as malondialdehyde, superoxide dismutase, glutathione peroxidase and Na+-K+-ATPase disorders induced by potassium cyanide. | Guangxin Miao Hongxiang Zhao Ke Guo Jianjun Cheng Shufeng Zhang Xiaofeng Zhang Zhenling Cai Hong Miao Yazhen Shang | 2014 | Neural Regeneration Research2014，9，17： | 8 |
| 7 | Secondary biogenic coalbed gas in some coal fields of China显示文摘The secondary biogenic coalbed gas, a new genetic and energy source type of coalbed gas in China, has been found in Xinji, Liyazhuang and Enhong areas. The essential characteristics of this type of gas are: (i) the major component of the gas is methane, with C1/C1-5 value higher than 0.99, indicating that the gas is part of dry gas; (ii) theδ13C1 value is in the range of -61.7‰to -47.9‰, mostly lower than -55‰, which is much lower than the estimatedδ13C1 value of thermogenic methane according to the thermal evolution degree of the coal rocks (with R0 value from 0.87% to 1.43%), showing the characteristics of the secondary biogenic gas; (iii) theδ5D value of methane ranges from -244‰to -196‰; (iv)δ13C 2 value ranges from -26.7‰to -15.9‰andδ13C 3 value ranges from -10.8‰to -25.3‰, indicating that the heavier hydrocarbons have a thermogenic origin; (v) the content of CO2 is very low, andδ13CCO2 value changes greatly, reflecting a characteristic of secondary change; (vi)δ15N2 value ranges mainly from -1‰to +1‰, indicating N2 derived significantly from air. The negative linear correlation between the contents of N2 and CH4 reflects the activity of bacteria bearing surface water infiltrating into coal beds. The comprehensive tracing indices show that the coalbed gas in the studied areas is the mixed gas of primarily secondary biogenic gas and a part of remnant thermogenic gas. The uplift of coal beds and the development of faults in the studied areas create favorable conditions for the formation of the secondary biogenic gas. | TAO Mingxin WANG Wanchun XIE Guangxin LI Jinying WANG Yanlong ZHANG Xiaojun ZHANG Hong SHI Baoguang GAO Bo | 2005 | Chinese Science Bulletin2005，50，S1： | 8 |
| 8 | Pretreatment with scutellaria baicalensis stem-leaf total flavonoid protects against cerebral ischemia/reperfusion injury in hippocampal neurons显示文摘Previous experimental studies have shown that cerebral infarction can be effectively reduced following treatment with scutellaria baicalensis stem-leaf total flavonoid(SSTF). However, the mechanism of action of SSTF as a preventive drug to treat cerebral infarction remains unclear. In this study, Sprague-Dawley rats were pretreated with 50, 100, 200 mg/kg SSTF via intragastric administration for 1 week prior to the establishment of focal cerebral ischemia/reperfusion injury. The results showed that pretreatment with SSTF effectively improved neurological function, reduced brain water content and the permeability of blood vessels, ameliorated ischemia-induced morphology changes in hippocampal microvessels, down-regulated Fas and Fas L protein expression, elevated the activity of superoxide dismutase and glutathione peroxidase, and decreased malondialdehyde content. In contrast to low-dose SSTF pretreatment, the above changes were most obvious after pretreatment with moderate- and high-doses of SSTF. Experimental findings indicate that SSTF pretreatment can exert protective effects on the brain against cerebral ischemia/reperfusion injury. The underlying mechanisms may involve reducing brain water content, increasing microvascular recanalization, inhibiting the apoptosis of hippocampal neurons, and attenuating free radical damage. | Xiangyu Kong Wei Kong Guangxin Miao Shumin Zhao Meng Chen Xiaoying Zheng Jiangtao Bai | 2014 | Neural Regeneration Research2014，9，23： | 7 |
| 9 | Effects of disinhibition on spatiotemporal pattern of neuronal first recruitment in neuronal networks显示文摘The propagation of neuronal activities is a key feature to understanding information processing in networks. The analysis based on first-spikes of bursts in turn plays an important role in the research of neuronal activity propagation. Our focus here is to investigate how spatiotemporal patterns of neuronal first-spikes are affected by disinhibition. Multi-electrode arrays were used to record stimulation-evoked bursts of multiple neurons in randomly cultured neuronal networks. Both the precise timing of and the rank relationships between first-spikes were analyzed. Compared with evoked bursts in the network's native state, the precise first-spike latencies in its dis-inhibited state are more consistent and the propagation of its bursting activities is much faster. Additional points of interest are that disinhibited neuronal networks can be evoked to generate stable and distinguishable neuronal first recruitment spatiotemporal patterns specific to the stimulation site, and that the disinhibition may cause the original spatiotemporal patterns to change in a heterogeneous manner with regards to different propagation pathways. | Liangbin Pana,b,c,1, Xindong Songa,b,c,1, Guangxin Xiang a,b,c, Jing Zhua,b,c, Jing Cheng a,b,c,d,a Medical Systems Biology Research Center, Tsinghua University School of Medicine, Beijing 100084, China b Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China c National Engineering Research Center for Beijing Biochip Technology, 18 Life Science Parkway, Beijing 102206, China d State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China | 2009 | Progress in Natural Science:Materials International2009，19，5： | 6 |
| 10 | Neuropeptide Y and leptin receptor expression in the hypothalamus of rats with chronic immobilization stress显示文摘In this study, Sprague-Dawley rats were immobilized to a frame for 3 hours a day for 21 days to establish a model of chronic immobilization stress. The body weight and food intake of rats subjected to chronic immobilization stress were significantly decreased compared with the control group. Dual-labeling immunofluorescence revealed that the expression of leptin receptor and the co-localization coeffient in these leptic receptor neurons in the arcuate nucleus of the hypothalamus were both upregulated, while the number of neuropeptide Y neurons was decreased. Chronic immobilization stress induced high expression of leptin receptor in the arcuate nucleus and suppressed the synthesis and secretion of neuropeptide Y, thereby disrupting the pathways in the arcuate nucleus that regulate feeding behavior, resulting in diminished food intake and reduced body weight. | Shaoxian Wang Jiaxu Chen Guangxin Yue Minghua Bai Meijing Kou Zhongye Jin | 2013 | Neural Regeneration Research2013，8，18： | 6 |
| 11 | BGMM: A Body Gauss-Markov Based Mobility Model for Body Area Networks显示文摘Existing mobility models have limitations in their ability to simulate the movement of Wireless Body Area Network(WBAN) since body nodes do not exactly follow either classic mobility models or human contact distributions. In this paper, we propose a new mobility model called Body Gauss–Markov Mobility(BGMM) model,which is oriented specially to WBAN. First, we present the random Gauss-Markov mobility model as the most suitable theoretical basis for developing our new model, as its movement pattern can reveal real human body movements. Next, we examine the transfer of human movement states and derive a simplified mathematical Human Mobility Model(HMM). We then construct the BGMM model by combining the RGMM and HMM models. Finally,we simulate the traces of the new mobility model. We use four direct metrics in our proposed mobility model to evaluate its performance. The simulation results show that the proposed BGMM model performs with respect to the direct mobility metrics and can effectively represent a general WBAN-nodes movement pattern. | Yi Liu Danpu Liu Guangxin Yue | 2018 | Tsinghua Science and Technology2018，23，3： | 4 |
| 12 | Joint beamforming and scheduling in the downlink of cognitive radio networks显示文摘Cognitive radio has been recently proposed as a promising technology to improve the spectrum utilization. In this paper, we consider a system where a licensed radio spectrum is shared by a primary network and a secondary network. Based on the subspace theory, a novel low-complexity algorithm for secondary user selection has been proposed. On the basis of the scheduling scheme, we jointly consider transmit beamforming, scheduling and power allocation, and subsequently present a complete set of solution for secondary network downlink. Simulation results has shown that our proposed scheme not only can limit the introduced interference at primary users within the tolerable range, but also can achieve high sum-rate throughput of secondary network, simultaneously. Furthermore, as is proved by simulation results, our scheme is very robust due to the fact that only a little tolerable performance drop is introduced when simple but nonoptimal equal power allocation is adopted. | XI Wei YIN ChangChuan YUE GuangXin | 2009 | Science in China(Series F)2009，52，12： | 4 |
| 13 | Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis显示文摘Homeobox A10(HOXA10)is a transcription factor belonging to the homeobox gene family.It is highly expressed in endometrial stromal cells(ESCs)and plays essential roles in the proliferation and differentiation of endometrium,the establishment of endometrial receptivity and embryo implantation.However,little is known about the target genes and signaling pathways regulated by HOXA10 in ESCs.In this study,we identified 1830 transcripts regulated by HOXA10 in ESCs by RNA interference(RNAi)and RNA-sequencing(RNA-seq)analysis,of which 980 were positively regulated by HOXA10 and 850 were negatively regulated by HOXA10.Interestingly,matrix metallopeptidase-11 was downregulated by HOXA10 in stromal cells verified by quantitative real-time polymerase chain reaction and western blot analysis.Pathway analysis demonstrated that the target genes were enriched in various pathways,including cellular metabolism,DNA replication and repair,cell junction,and lysosome and signal transduction.The results of the present study provide novel insights into the mechanism underlying HOXA10 regulation in ESCs and may identify novel targets for the diagnosis and treatment of endometrium-related infertility. | Yuan Wang Shuanggang Hu Guangxin Yao Yun Sun | 2021 | Acta Biochimica et Biophysica Sinica2021，53，3： | 3 |
| 14 | Simulation and evaluation of the water purification function of Zhalong Wetland based on a combined water quantity-quality model显示文摘The water purification function of natural wetland systems is widely recognized,but rarely studied or scientifically evaluated.Extensive studies have been carried out by various international wetland research communities to quantify the water quality improvement ability of the natural wetlands,in order to maintain such ability and wetland ecological health.This study aims to evaluate the purification function of Zhalong Wetland in China for removing total nitrogen(TN) and phosphorus(TP),based on ex-situ experiments and the development of a combined water quantity-quality model.Experiments and model predictions were carried out with different input TP and TN concentrations.Statistical analyses demonstrated that the relative errors between model simulations and experimental observations for TN and TP were 8.6% and 12.4%,respectively.With water retention time being maintained at 90 d,the removal rate of these pollutants could not reach the required Grade V standards,if the inflow TN concentration was over 42 mg L-1,or the input TP concentration was over 14 mg L-1.The simulation results also demonstrated that,even with Grade V quality standard compliance,when the water inflow from surrounding industries and agriculture lands into Zhalong Wetland reaches 0.3×10 8 m 3 a-1,the maximum TN and TP loads that the reserve can cope with are 1.26×10 3 t a-1 and 0.42×10 3 t a-1,respectively.Overall,this study has produced a significant amount of information that can be used for the protection of water quality and ecological health of Zhalong Wetland. | LI HongYan ZHANG GuangXin SUN GuangZhi | 2012 | Science China(Technological Sciences)2012，55，7： | 3 |
| 15 | Robust state-space realizations of digital filters against finite word length errors显示文摘This article deals with two important issues in digital filter implementation:roundoff noise and limit cycles. A novel class of robust state-space realizations, called normal realizations, is derived and characterized. It is seen that these realizations are free of limit cycles. Another interesting property of the normal realizations is that they yield a minimal error propagation gain. The optimal realization problem, defined as to find those normal realizations that minimize roundoff noise gain, is formulated and solved analytically. A design example is presented to demonstrate the behavior of the optimal normal realizations and to compare them with several well-known digital filter realizations in terms of minimizing the roundoff noise and the error propagation. | He Xiongxiong Li Gang Zhu Guangxin Wan Chunru | 2008 | Journal of Systems Engineering and Electronics2008，19，5： | 3 |
| 16 | Preparation and SO2 Adsorption Behavior of Coconut Shell-Based Activated Carbon via Microwave-Assisted Oxidant Activation显示文摘A series of oxidants supported on coconut shell-based activated carbon(CAC) through microwave irradiation were prepared and characterized using scanning electron microscopy(SEM), N_2 adsorption/desorption analysis, and X-ray photoelectron spectroscopy(XPS). The SO_2 adsorption capacities and rates were evaluated by adsorption tests performed in a fixed bed reactor with a simulated flue gas, and the adsorption isotherm models were validated against the experimental results. The findings revealed that the SO_2 adsorption capacity decreased in the following order: MW-K_2Cr_2O_7-CAC > MWKMnO_4-CAC > MW-H_2O_2-CAC > MW-CAC. The SO_2 adsorption capacities and adsorption rates of the samples increased with an increasing oxidizability of the oxidants owing to the increment of mean pore size and oxygen-containing functional groups. In addition, a high initial SO_2 concentration and a low bed temperature could positively affect the SO2 adsorption. Finally, the Langmuir model validated that SO_2 was mainly adsorbed through chemical adsorption on the sample surfaces. | Jia Fengrui Li Zhou Wang Engang He Jicheng Dong Hui Liu Guangxin Jian Weiwei | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，1： | 3 |
| 17 | Synthesis of Isoquinoline-1, 3-Dicarboxylic Acid显示文摘Two new compounds, isoquinoline-1, 3-dicarboxyaldehyde and (IDA) were synthesizedvia 6 or 7 steps starting from benzaldehyde, or prepared via 4 steps starting from allylbenzene. | Xian Hong YINI Man Ya YANG Hua Hong SHI Lian Quan GU(Chemistry Department, Zhongshan University. Guangzhou 510275)(Chemistry Department, Guangxin University for Nationalities, Nanning 530006) | 1999 | Chinese Chemical Letters1999，10，11： | 2 |
| 18 | Visible Light Driven Copper(I )Catalyzed Oxyamination of Electron Deficient Alkenes显示文摘Summary of main observation and conclusion A vible light driven Cu()-catalyzed intermolecular oxyamination of electron-deficient olefins has been achieved by using O-benzoylhydroxylamines as donors both for amine and oxygen.The transformation properties afford mild conditions and a wide substrate scope,providing access to ester derivatives of 6-amino alcohols with good yields and high regioselectivity. | Sanliang Li Qiaoyu Chen Wenbo Li Guangxin Gu Junliang Zhang | 2020 | Chinese Journal of Chemistry2020，38，10： | 2 |
| 19 | Influence of Cr^(3+) Concentration on SO_2 Removal over TiO_2 Based Multi-walled Carbon Nanotubes显示文摘In this study, titanium dioxide supported by multi-walled carbon nano tubes(MWCNTs/TiO_2) and Cr-doped TiO_2 supported by MWCNTs(MWNTs/Cr-TiO_2) were synthesized by the sol-gel method. The prepared samples were characterized by transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, the BrunauerEmmett-Teller analysis, and the Raman spectroscopy. The oxidation and efficiency for removal of SO_2 in a simulated flue gas were investigated experimentally in a fixed-bed reactor. The 15% MWCNTs/Cr-Ti02 sample displayed excellent adsorption properties, and a SO_2 removal rate equating to 30.415 1 mg/g from the simulated flue gas containing 2 300 μg/g of SO_2, 8% of 02, and 5% of H20 was achieved under optimal conditions covering a temperature of 333.15 K, and a space velocity of 1 275 h^(-1). The adsorption process was enhanced because Cr doping modified the pore structure and inhibited the grain growth of TiO_2. In addition, the Freundlich and Langmuir models revealed that SO_2 was mainly adsorbed through chemical adsorption on the sample surfaces, and the thermodynamic model analysis indicated that the adsorption was a spontaneous, exothermic, and entropy-reducing process. The adsorption kinetics of SO_2 can be described by the pseudosecond-order kinetic and the Bangham dynamics models. The possible reaction mechanism involved in desulfurization process was also proposed. | Yang Yanchun Jia Fengrui Jian Weiwei Zhang Shaopeng Ma Danzhu Liu Guangxin | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，1： | 2 |
| 20 | An innovative way of etching MoS2: Characterization and mechanistic investigation显示文摘 | Yuan Huang Jing Wu Xiangfan Xu Yuda Ho Guangxin Ni Qiang Zou Gavin Kok Wai Koon Weijie Zhao A. H. Castro Neto Goki Eda Chengmin Shen Barbaros Ozyilmaz | 2013 | Nano Research2013，6，3： | 2 |
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