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| 1 | Effect mechanisms of micro-alloying element La on microstructure and mechanical properties of hypoeutectic Al-Si alloys显示文摘The rare earth influence on the as-cast micro structures and mechanical properties of aluminum alloys attracted great attentions in the last decades.But up to date no reports can be found on the effect of microalloying element La(La addition is below 0.1 wt.%) on the solidification of hypoeutectic Al-Si alloys.This study carried out solidification experiments with Al-6 Si alloys micro-alloyed by element La.The α-Al grain refinement,the eutectic Si modification and the tensile properties improvement caused by microalloying element La were investigated.The effect mechanisms of La were discussed.It is demonstrated that the addition of La as low as 100 ppm can deprave the more effective heterogeneous nucleation conditions for the eutectic Si caused by the impurity P.The addition of 0.06 wt.% La is sufficient to achieve an ideal α-Al grain refinement,eutectic Si modification and ductility improvement of the alloys.LaAlSi phase forms in the Al-Si alloy with the additive amount of La higher than 0.06 wt.%.It has a tetragonal structure.Micro-alloying element La refines the α-Al grains by working as a surfactant and modifies the eutectic Si by promoting the formation of the significant multiple Si twins. | Qiuju Zheng Lili Zhang Hongxiang Jiang Jiuzhou Zhao Jie He | 2020 | Journal of Materials Science & Technology2020，47，12： | 18 |
| 2 | A 2-kb Mycovirus Converts a Pathogenic Fungus into a Beneficial Endophyte for Brassica Protection and Yield Enhancement显示文摘Mycoviruses are viruses that infect fungi,and hypovirulence-associated mycoviruses have the potential to control fungal diseases.However,it is unclear how mycovirus-mediated hypovirulent strains live and survive in the field,and no mycovirus has been applied for field crop protection.In this study,we found that a previously identified small DNA mycovirus(SsHADV-1)can convert its host,Sclerotinia sclerotiorum,from a typical necrotrophic pathogen to a beneficial endophytic fungus.SsHADV-1 downregulates the expression of key pathogenicity factor genes in S.sclerotiorum during infection.When growing in rapeseed,the SsHADV-1-infected strain DT-8 significantly regulates the expression of rapeseed genes involved in defense,hormone signaling,and circadian rhythm pathways.As a result,plant growth is promoted and disease resistance is enhanced.Field experiments showed that spraying DT-8 at the early flowering stage can reduce the disease severity of rapeseed stem rot by 67.6%and improve yield by 14.9%.Moreover,we discovered that SsHADV-1 could also infect other S.sclerotiorum strains on DT-8-inoculated plants and that DT-8 could be recovered from dead plants.These findings suggest that the mycoviruses may have the ability to shape the origin of endophytism.Our discoveries suggest that mycoviruses may influence the origin of endophytism and may also offer a novel strategy for disease control in which mycovirus-infected strains are used to improve crop health and release mycoviruses into the field. | Hongxiang Zhang Jiatao Xie Yanping Fu Jiasen Cheng Zheng Qu Zhenzhen Zhao Shufen Cheng Tao Chen Bo Li Qianqian Wang Xinqiang Liu Binnian Tian David B.Collinge Daohong Jiang | 2020 | Molecular Plant2020，13，10： | 9 |
| 3 | Mechanisms underlying attenuation of apoptosis of cortical neurons in the hypoxic brain by flavonoids from the stems and leaves of Scutellaria baicalensis Georgi显示文摘Flavonoids from the stems and leaves of Scutellaria baicalensis Georgi, an antioxidant, markedly improve memory impairments and neuronal injuries. In the present study, primary cortical neurons of rats were exposed to potassium cyanide to establish a model of in vitro neural cell apoptosis. Inhibition of apoptosis by flavonoids from the stems and leaves of Scutellaria baicalensis Georgi at concentrations of 18.98, 37.36, and 75.92 μg/mL was detected using this model. These flavonoids dramatically increased cell survival, inhibited cell apoptosis and excessive production of malondialdehyde, and increased the activities of superoxide dismutase, glutathione peroxidase, and Na+-K+-ATPase in primary cortical neurons exposed to potassium cyanide. The flavonoids from the stems and leaves of Scutellaria baicalensis Georgi were originally found to have a polyhydric structure and to protect against cerebral hypoxia in in vitro and in vivo models, including hypoxia induced by potassium cyanide or cerebral ischemia. The present study suggests that flavonoids from the stems and leaves of Scutellaria baicalensis Georgi exert neuroprotective effects via modulation of oxidative stress, such as malondialdehyde, superoxide dismutase, glutathione peroxidase and Na+-K+-ATPase disorders induced by potassium cyanide. | Guangxin Miao Hongxiang Zhao Ke Guo Jianjun Cheng Shufeng Zhang Xiaofeng Zhang Zhenling Cai Hong Miao Yazhen Shang | 2014 | Neural Regeneration Research2014，9，17： | 8 |
| 4 | Quantitative trait loci for Fusarium head blight resistance in wheat cultivars Yangmai 158 and Zhengmai 9023显示文摘Fusarium head blight(FHB)is one of the prevalent fungal diseases of wheat worldwide.Exploring new FHB resistance quantitative trait loci(QTL)in adapted wheat cultivars is a critical step for breeding new FHB-resistant cultivars.In this study,we developed a population of 236 F5:7 recombinant inbred lines(RILs)using two popular Chinese wheat cultivars,Yangmai 158 and Zhengmai 9023,with moderate FHB resistance to identify the QTL for FHB type II resistance.This population was evaluated for percentage of symptomatic spikelets per spike(PSS)using single floret injection in repeated greenhouse experiments.Mean PSSs were 33.2%for Yangmai 158 and 30.3%for Zhengmai 9023.A genetic linkage map of 1002 single nucleotide polymorphisms(SNPs)generated by genotyping-by-sequencing(GBS)was constructed for the RIL population.Six QTL were identified for FHB resistance,and three of them were repeatable in the both experiments.Zhengmai 9023 contributed the resistance allele at one repeatable QTL,designated as Qfhb.7D,whereas Yangmai 158 contributed the resistance alleles at the other two repeatable QTL,Qfhb.3AL and Qfhb.2DS.The additional QTL,Qfhb.4AS was significant in the mean PSS,and Qfhb.2DL and Qfhb.7AS were significant in only one experiment.Replacement of each allele individually at the three repeatable QTL significantly changed PSSs.Qfhb.3AL,Qfhb.2DS,and Qfhb.7D explained 8.35%to 9.89%,5.13%to 7.43%,and 6.15%to 9.32%of the phenotypic variations,respectively.The three repeatable QTL contributed by the two parents were additive and stacking the resistance alleles from all the three repeatable QTL showed the highest level of resistance in the current RIL population.Ten SNPs in the QTL regions of Qfhb.3AL,Qfhb.2DS,and Qfhb.7D were converted into KBioscience competitive allele-specific PCR(KASP)assays.One KASP marker for Qfhb.3AL was validated in a panel of wheat cultivars from China.Some of these KASP markers could be useful for marker-assisted selection to stack these QTL. | Pingping Zhang Chenjin Guo Zhao Liu Amy Bernardo Hongxiang Maa Hongxiang Ma Peng Jiang Guicheng Song Guihua Bai | 2021 | The Crop Journal2021，9，1： | 8 |
| 5 | Bio-inspired polygonal skeleton structure for vibration isolation:Design,modelling,and experiment显示文摘Inspired by the safe landing of a cat falling from a high altitude,a bio-inspired polygonal skeleton(BIPS) structure is proposed,and its nonlinear characteristics are systematically studied to explore its potential application in the suppression of vibration. The polygon is formed by the skeleton structure of the cat’s entire body and the ground. The BIPS system consists of two symmetrical bionic legs with three robs(as skeleton) and four horizontal springs(as muscle). Two bionic legs are connected through the bearing platform(as spine),which could adjust the distance between the two bionic legs. A theoretical model is developed to characterize its stiffness nonlinearity through geometrical and mechanical analysis. Parameter analysis reveals that the BIPS structure has diverse stiffness,including nonlinear positive stiffness and negative stiffness. By imitating adjustment of leg posture and telescopic function of the spine(control the distance between legs),these flexible stiffness properties can be adjusted by structure parameters. In addition,the load capacity and working range can also be designed by the length of the bars,the initial angle,the mounting position,and the spring stiffness. The experimental setup is established,and the vibration isolation performance under various excitation is tested. The experimental results verify the accuracy of the dynamic model and also show that the proposed BIPS structure can suppress the vibration effectively under a variety of excitations. These peculiarities may provide potential possibility of an innovative approach to passive vibration control and isolation. | YAN Ge WANG Sen ZOU HongXiang ZHAO LinChuan GAO QiuHua ZHANG WenMing | 2020 | Science China(Technological Sciences)2020，63，12： | 5 |
| 6 | Microstructure formation and electrical resistivity behavior of rapidly solidified Cu-Fe-Zr immiscible alloys显示文摘The immiscible Cu-Fe alloy was characterized by a metastable miscibility gap.With the addition element Zr,the miscibility gap can be extended into the Cu-Fe-Zr ternary system.The effect of the atomic ratio of Cu to Fe and Zr content on the behavior of liquid-liquid phase separation was studied.The results show that liquid-liquid phase separation into Cu-rich and Fe-rich liquids took place in the as-quenched Cu-Fe-Zr alloy.A glassy structure with nanoscale phase separation was obtained in the as-quenched(Cu0.5Fe0.5)40Zr60 alloy sample,exhibiting a homogeneous distribution of glassy Cu-rich nanoparticles in glassy Fe-rich matrix.The microstructural evolution and the competitive mechanism of phase formation in the rapidly solidified Cu-Fe-Zr system were discussed in detail.Moreover,the electrical property of the as-quenched Cu-Fe-Zr alloy samples was examined.It displays an abnormal change of electrical resistivity upon temperature in the nanoscale-phase-separation metallic glass.The crystallization behavior of such metallic glass has been discussed. | Xiaojun Sun Jie He Bin Chen Lili Zhang Hongxiang Jiang Jiuzhou Zhao Hongri Hao | 2020 | Journal of Materials Science & Technology2020，44，9： | 5 |
| 7 | Design,modeling and experimental investigation of a magnetically modulated rotational energy harvester for low frequency and irregular vibration显示文摘Vibration energy harvesting is a promising approach for sustainable energy generation from ambience to meet the development of self-powered systems.Here,we propose a novel compact non-resonant magnetically modulated rotational energy harvester(MMR-EH)for low frequency and irregular vibration.Through the rational arrangement of multiple magnetic fields in space,a ring route with low potential energy is established.A movable magnet can be non-contact modulated by the magnetic force to move along the ring route under irregular vibration,which is instrumental in electromechanical energy conversion.A dynamic model of the MMR-EH is developed based on the energy method and verified experimentally.The effects of key parameters on the magnetically modulated route are analysed.The simulation and experimental results demonstrate that the MMR-EH can effectively harvest the energy from ultra-low frequency(3 Hz)and irregular vibration.At a reciprocating vibration frequency of 10 Hz and an amplitude of 20 mm,the harvester can produce an average power of 0.29 mW. | ZHAO LinChuan ZOU HongXiang GAO QiuHua YAN Ge WU ZhiYuan LIU FengRui WEI KeXiang YANG Bin ZHANG WenMing | 2020 | Science China(Technological Sciences)2020，63，10： | 5 |
| 8 | Solidification Behavior of Immiscible Alloys under the Effect of a Direct Current显示文摘Directional solidification experiments were carried out with Al—Pb alloys under the effect of a direct current(DC).The experimental results show that the DC causes a migration of the minority phase droplets(MPDs) from the middle part to the surface region of the sample.Samples with either a finely dispersed microstructure or a shell/core structure were obtained by solidifying the alloy under the effect of the properly selected DC densities.A model was developed to describe the microstructure evolution in an immiscible alloy directionally solidified under the effect of the DC.The microstructure formation in the Al—Pb alloys was calculated.The numerical results are in favorable agreement with the experimental ones.They demonstrate that the DC affects the microstructure formation mainly through changing the spatial motions of the MPDs and the temperature field of the melt in front of the solid/liquid interface.The formation mechanisms of the finely dispersed microstructure as well as the shell/core structure were sufficiently clarified. | Hongxiang Jiang Jiuzhou Zhao Jie He | 2014 | Journal of Materials Science & Technology2014，30，10： | 4 |
| 9 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 10 | Opaque virtual network mapping algorithms based on available spectrum adjacency for elastic optical networks显示文摘Optical network virtualization enables multiple virtual optical networks constructed for different infrastructure users(renters) or applications to coexist over a physical infrastructure. Virtual optical network(VON) mapping algorithm is used to allocate necessary resources in the physical infrastructure to the VON requests(VRs). In this paper, we investigate the opaque VON mapping problems in elastic optical networks(EONs). Based on the concept of available spectrum adjacency(AvS A) on links or paths, we consider both node resource and AvS A on links for node mapping, and present a link mapping method which chooses the routing and spectrum plan whose AvS A on paths is the largest among all the candidates. Finally, the overall VON mapping algorithm(i.e., AvS A-opaque VON mapping, AvS A-OVONM) coordinated node and link mapping is proposed. Extensive simulations are conducted and the results show that AvS A-OVONM has better performance of blocking probability and revenue-to-cost ratio than current algorithms. | Hongxiang WANG Jingxi ZHAO Hui LI Yuefeng JI | 2016 | Science China(Information Sciences)2016，59，4： | 3 |
| 11 | Effect of micro-alloying La on precipitation behavior, mechanical properties and electrical conductivity of Al-Mg-Si alloys显示文摘The rapid industrial development calls for alloys that possess higher comprehensive properties. In this study, the effect of microalloying La addition on the precipitation behavior during artificial aging as well as the mechanical properties and electrical conductivity of Al-Mg-Si alloys were investigated by thermal analysis, microstructural characterizations and properties tests.The results demonstrated that micro-alloying La addition does not change the whole precipitation sequence during the artificial aging of Al-Mg-Si alloys as well as the atomic structure of the precipitates. However, the higher La-vacancy binding energy as well as the strong La-Si and La-Mg interactions can decrease the solubility of Si and Mg in the Al matrix and the β″ precipitation activation energy from 89.9 to 76.7 kJ/mol, leading to the improvement of the strength and electrical conductivity of Al-Mg-Si alloys simultaneously. The microstructural features affecting the strength and electrical conductivity were theoretically discussed in terms of the La addition. | ZHENG QiuJu JIANG HongXiang HE Jie ZHANG LiLi ZHAO JiuZhou | 2021 | Science China(Technological Sciences)2021，64，9： | 3 |
| 12 | Development and validation of a UPLC–MS/MS assay for the determination of gemcitabine and its L-carnitine ester derivative in rat plasma and its application in oral pharmacokinetics显示文摘A simple and rapid UPLC–MS/MS method to simultaneously determine gemcitabine and its L-carnitine ester derivative(2’-deoxy-2’, 2’-difluoro-N-((4-amino-4-oxobutanoyl) oxy)-4-(trimethyl amm-onio) butanoate-cytidine, JDR) in rat plasma was developed and validated.The conventional plasma sample preparation method of nucleoside analogues is solidphase extraction(SPE) which is time-consuming and cost-expensive. In this study, gradient elution with small particles size solid phase was applied to effectively separate gemcitabine and JDR, and protein precipitation pretreatment was adopted to remove plasma protein and extract the analytes with high recovery(>81%). Method validation was performed as per the FDA guidelines, and the standard curves were found to be linear in the range of 5–4000 ng/ml for JDR and 4–4000 ng/ml for gemcitabine, respectively. The lower limit of quantitation(LLOQ)of gemcitabine and JDR was 4 and 5 ng/ml, respectively. The intra-day and inter-day precision and accuracy results were within the acceptable limits. Finally, the developed method was successfully applied to investigate the pharmacokinetic studies of JDR and gemcitabine after oral administration to rats. | Gang Wang Dongyang Zhao Hongxiang Chen Dawei Ding Longfa Kou Lifang Sun Chenxia Hao Xincong Li Kai Jia Qiming Kan Xiaohong Liu Zhonggui He Jin Sun | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，5： | 2 |
| 13 | Global woodland structure from local interactions:new nearest-neighbour functions for understanding the ontogenesis of global forest structure显示文摘Background:A number of hypotheses and theories,such as the Janzen-Connell hypothesis,have been proposed to explain the natural maintenance of biodiversity in tropical and temperate forest ecosystems.However,to date the details of the processes behind this natural maintenance are still unclear.Recently two new nearest-neighbour characteristics were proposed and in this paper we demonstrate how they can contribute to a better understanding of the ontogenesis of global forest structure from localised neighbourhoods.Methods:We applied the new species and size segregation functions together with appropriate test procedures to four example woodland data sets from China at Daqingshan,Jiaohe,Jiulongshan and Xiaolongshan forest regions.In addition we quantified the morphology of the new characteristics and modelled a neighbourhood allometric coefficient linking the two functions.Results:The results revealed quite different species segregation patterns with both conspecific and heterospecific attraction.We found these to be generally matched by equivalent size segregation patterns of attraction of similar and different sizes.It was straightforward to model the size segregation function from the knowledge of the species segregation function by estimating a neighbourhood allometric coefficient.Conclusions:The new characteristics have helped to quantify the extent and rate of decline of neighbourhood interactions in terms of spatial species and size diversity.Through the allometric neighbourhood coefficient the analysis highlighted once more how closely related species and size segregation are,thus supporting the minglingsize hypothesis.Using both a traditional and a restricted random-labelling test has provided a valuable tool for understanding the exact nature of species-mingling and size-inequality relationships. | Arne Pommerening Hongxiang Wang Zhonghua Zhao | 2020 | Forest Ecosystems2020，7，2： | 1 |
| 14 | Si nanoparticles seeded in carbon-coated Sn nanowires as an anode for high-energy and high-rate lithium-ion batteries显示文摘High-capacity and high-rate anode materials are desperately desired for applications in the next generation lithium-ion batteries.Here,we report preparation of an anode showing a structure of Si nanoparticles wrapped inside Sn nanowires.This anode inherits the advantages of both Si and Sn,endowing lithiation/delithiation of Si nanoparticles inside the conducting networks of Sn nanowires.It demonstrates a high and reversible capacity of∼1500 mAh g−1 over 300 cycles at 0.2℃ and a good rate capability(0.2℃–5℃)equivalent to Sn.The excellent cycling performance is attributed to the novel structure of the anode as well as the strong mechanical strength of the nanowires which is directly confirmed by in-situ lithiation and bending experiments. | Liubin Ben Jin Zhou Hongxiang Ji Hailong Yu Wenwu Zhao Xuejie Huang | 2022 | Materials Futures2022，1，1： | 1 |
| 15 | Quantification of prio n gene expression in brain and peripheral organs of golden hamster by real-time RT-PCR显示文摘 | Ning Zhanyong Zhao Deming Liu Hongxiang | 2005 | Animal Biotechnology2005，16，： | 1 |
| 16 | Impact toughness of a gradient hardened layer of Cr5Mo1V steel treated by laser shock peening显示文摘Laser shock peening(LSP) is a widely used surface treatment technique that can effectively improve the fatigue life and impact toughness of metal parts.Cr5Mo1 V steel exhibits a gradient hardened layer after a LSP process.A new method is proposed to estimate the impact toughness that considers the changing mechanical properties in the gradient hardened layer.Assuming a linearly gradient distribution of impact toughness,the parameters controlling the impact toughness of the gradient hardened layer were given.The influence of laser power densities and the number of laser shots on the impact toughness were investigated.The impact toughness of the laser peened layer improves compared with an untreated specimen,and the impact toughness increases with the laser power densities and decreases with the number of laser shots.Through the fracture morphology analysis by a scanning electron microscope,we established that the Cr5Mo1 V steel was fractured by the cleavage fracture mechanism combined with a few dimples.The increase in the impact toughness of the material after LSP is observed because of the decreased dimension and increased fraction of the cleavage fracture in the gradient hardened layer. | Weiguang Xia Lei Li Yanpeng Wei Aimin Zhao Yacong Guo Chenguang Huang Hongxiang Yin Lingchen Zhang | 2016 | Acta Mechanica Sinica2016，32，2： | 1 |
| 17 | Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles显示文摘 | HouLi Li XiaoBin Zhao YuKun Ma GuangXi Zhai LingBing Li HongXiang Lou | 2008 | Journal of Controlled Release2008，，3： | 1 |
| 18 | Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin显示文摘 | Anchang Liu Hongxiang Lou Lixia Zhao Peihong Fan | 2005 | Journal of Pharmaceutical and Biomedical Analysis2005，，3： | 1 |
| 19 | Metal recycling from waste memory modules efficiently and environmentally friendly by low-temperature alkali melts显示文摘Recycling of waste electrical and electronic equipment has become an urgent global issue in recent years from the prospectives of resources recycling and environmental protection.In the present work,the recycling of waste memory modules(WMMs)through low-temperature alkali melts was investigated,based on the thermodynamic analysis of the nonmetallic reactions of brominated epoxy resin,glass fiber and memory chip with the molten mixed alkali.The effects of the reaction temperature and the ratio of alkali mixture on the removal rate of nonmetallic parts in WMMs were discussed under the condition of air atmosphere.The optimum process parameters were further confirmed by in-situ monitoring of the temperature during the whole reaction process.The mixtures with Cu,Fe and Ni as the main components were obtained after the treatment of WMMs in the molten alkali.These mixed metals were further separated into copper-rich and ferronickel-rich metals by physical magnetic separation.Moreover,the precious metals Au and Ag were enriched in Cu-rich alloys.This work provided an efficient and environment-friendly method for metal recycling from WMMs. | ZHU MingWei MA HaoBo HE Jie CHEN Bin ZHANG LiLi JIANG HongXiang SUN XiaoJun ZHAO JiuZhou | 2020 | Science China(Technological Sciences)2020，63，11： | 1 |
| 20 | Quantification of prion gene expression in brain and peripheral organs of golden hamster by real-time RT-PCR显示文摘 | Ning Zhanyong Zhao Deming Liu Hongxiang | 2005 | Animal Biotechnology2005，16，： | 1 |
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