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| 1 | Antiviral activity of traditional Chinese medicinal plants Dryopteris crassirhizoma and Morus alba against dengue virus显示文摘Dengue virus(DENV) has emerged as a major virus that is spread by mosquitoes. Recently, it has spread to more than a hundred nations but continues to lack specific treatable medication. Many traditional Chinese medicinal(TCM) plants are in practice for dengue fever in dengue endemic regions. These traditional medicines persevere with treatments, which modern medicines lack. The study aims to substantiate the anti-dengue potential of some traditional herbs and make them available for further studies to facilitate TCM users. Twelve TCM plants aqueous extracts were evaluated, which are described as cool herbs used for the diseases with high fever. Lead plants were established through detailed in vitro foci forming unit reduction analysis(FFURA) against all four serotypes and validated through quantitative real-time RT-PCR(q RT-PCR). Four plants potentially inhibited the virus in primary phenotypic in vitro evaluation. Two lead plants Dryopteris crassirhizoma(DC) and Morus alba(MA) were identified with half minimal inhibitory concentration(IC50) 130 and 221 μg m L^-1, respectively, while the selectivity indices(SI) were 4.21 and 4.62, respectively. Lead plants equally inhibited all four serotypes of DENV. Time-of-addition analysis suggested that, DC was active at later stages of viral replication, whereas MA was active during the early stages and even showed some prophylactic activity. Liquid chromatography-mass spectrometry(HPLC/MS) analysis revealed presence of flavonoids. DC and MA are identified as potential anti-dengue plants, active against varied stages of dengue virus replication cycle. These results may serve as the base knowledge for further investigation on their combined treatments or integrative treatment with western medicines, which may improve the overall anti-dengue activity in future. | Maqsood MARYAM Kian Keong TE Fai Chu WONG Tsun Thai CHAI Gary K K LOW Seng Chiew GAN Hui Yee CHEE | 2020 | Journal of Integrative Agriculture2020，19，4： | 1 |
| 2 | Adverse events over two years after retropubic or transobturator midurethral sling surgery: findings from the Trial of Midurethral Slings (TOMUS) study显示文摘 | Linda Brubaker Peggy A. Norton Michael E. Albo Toby C. Chai Kimberly J. Dandreo Keith L. Lloyd Jerry L. Lowder Larry T. Sirls Gary E. Lemack Amy M. Arisco Yan Xu John W. Kusek | 2011 | American Journal of Obstetrics and Gynecology2011，，5： | 1 |
| 3 | 轻松自主度假天堂显示文摘一直觉得,东南亚的度假酒店水准十分参差,虽然选址都是一些风景很不错的地方,但论及酒店本身的设计,却没有很大日突破,即使是一些夸国联营大集团,旗下的resort有时亦稍嫌公式化,虽说是装潢漂亮优美,却不一定有自家的味道特色。但近年其实已兴起一些较独立经营的度假酒店(部分属于一些较小规模的新兴hotel chain),反而有点异军突起的感觉,不但选址方面更大胆,敢于离开热门的度假胜地,更在设计上另辟蹊径,扩阔思维,不再囿于一般度假酒店的框框。 | 三三 Gary Chai | 2008 | 明日风尚2008，0，4： | 0 |
| 4 | Optimising local council's return on investment from annual pavement rehabilitation budgets through targeting of the average pavement condition index显示文摘A high quality transportation system is necessary in a modern economy,and a road network is a common and significant,component of the system.Road systems have two major objectives:to enable the movement of passenger vehicles and the movement of freight vehicles at reasonable speeds.An important part of the transportation system and an expensive investment,a functional road network must meet both objectives to maintain an efficient economy.In Australia,the Department of Infrastructure and Regional Development reported that,in 2011/12,the total road length was approximately900,000 km,and the total road expenditure was approximately $19 billion.Good policy requires that infrastructure investments provide a return on investment,thus warranting judicious management to ensure that it is maintained in a cost effective manner.Recent studies in Queensland,Australia,have identified differences between financial and engineering professionals in their understanding of infrastructure depreciation,condition deterioration,and future funding needs.Furthermore,the Queensland Asset Sustainability Ratio(ASR) requires clearer definitions to ensure that infrastructure remains meaningful to all users.This study proposes a separate sustainability index for road pavements(SIR)unlike the ASR that combines all type of assets.The justification is our ability to assess road condition,the high value of road assets,relative value to other infrastructure,and advanced knowledge of deterioration relative to other infrastructure.The SIR involves community consultation to target an average pavement condition index(PCI).This study also provides an alternative method to determine the optimal target PCI for a localgovernment authority(LGA) that balances community expectations and funding levels,with a particular focus on return on investment(ROI) for the annual road reseal and rehabilitation budget. | Gregory Kelly Deborah Delaney Gary Chai Sherif Mohamed | 2016 | Journal of Traffic and Transportation Engineering(English Edition)2016，3，5： | 0 |
| 5 | Concept Paper: Developing Pavement Structural Deterioration Curves显示文摘 | Gregory Kelly Gary Chai Sittampalam Manoharan Deborah Delaney Sanaul Chowdhury | 2018 | Journal of Civil Engineering and Architecture2018，12，7： | 0 |
| 6 | 澳大利亚低交通量道路就地稳定技术的成本效益分析显示文摘长期以来,澳大利亚和世界很多地方的工程师都利用就地稳定技术进行路面施工和修复。因其成本低,很多路面管理者也都会优先考虑这一技术。本文提出了一种评估工程和路面修复直接成本的方法,可以帮助决策者在路面养护时选择不同的施工技术。文章还对水泥就地稳定技术和其他路面修复方法进行了成本效益分析,并比较了再生技术对路面结构的影响。稳定后的路面厚度应符合澳大利亚稳定行业协会颁布的《路面设计暂行规定》(AustStab,2006)。文章最后还提到了澳大利亚(2004)新颁布的《水泥路面力学设计细则》。 | Gary Chai Warren Smith 赵娟 | 2007 | 交通建设与管理2007，0，Z1： | 0 |
| 7 | An Easy to Implement Sustainability Index for Flexible Pavements显示文摘 | Gregory Kelly Gary Chai Deborah Delaney | 2017 | Journal of Civil Engineering and Architecture2017，11，12： | 0 |
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