| 1 | Image texture smoothing method by a novel L0-norm optimization model显示文摘Texture smoothing is a fundamental tool in various applications. In this work, a new image texture smoothing method is proposed by defining a novel objective function, which is optimized by L0-norm minimization and a modified relative total variation measure. In addition, the gradient constraint is adopted in objective function to eliminate the staircase effect, which can preserve the structure edges of small gradients. The experimental results show that compared with the state-of-the-art methods, especially the L0 gradient minimization method and the relative total variation method, the proposed method achieves better results in image texture smoothing and significant structure preserving. | 聂栋栋 Ge Xindi Zhang Tianlai | 2020 | High Technology Letters2020，26，3： | 1 |
| 2 | Facile fabrication of drug-loaded PEGDA microcapsules for drug evaluation using droplet-based microchip显示文摘Droplet-based microfluidic technology can be utilized as a microreactor to prepare novel functional monodisperse microcapsules.In this study,a droplet-based microfluidic chip with surface modification,which allowed the one-step preparation of double emulsion microcapsules.An O/W/O double emulsion using polyethylene(glycol)diacrylate(PEGDA)solution as the intermediate water phase was prepared by regulating the hydrophilicity and hydrophobicity of the chip surface,with PEGDA microcapsules prepared using UV polymerization.And then anti-tumor drug paclitaxel and neurotoxin 6-OHDA were encapsulated in microcapsules for drug and toxicology evaluation,respectively.Compared to controls,drug-loaded mi-crocapsules caused a significant increase in the death rate of PC12 cells.This indicates that the obtained drug-loaded microcapsules could be used in drug evaluation and potentially in drug screening and deliv-ery. | Xindi Sun Qirui Wu Wei Li Xiuqing Gong Jun-Yi Ge Jinbo Wu Xinghua Gao | 2022 | Chinese Chemical Letters2022，33，5： | 0 |
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