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| 1 | Serum cytokine profile in patients with hepatitis B e antigen-negative chronic active hepatitis B and inactive hepatitis B virus carriers显示文摘An insufficient cellular immune response seems to be critical for the immunopathogenesis of chronic hepatitis B virus infection.We have previously demonstrated no differences of T-lymphocyte subsets in blood between inactive hepatitis B s antigen(HBsAg) carriers and patients with HBeAg-negative chronic active hepatitis B.This study investigated the peripheral blood cytokine profile in patients with HBeAg-negative chronic active hepatitis B infection(Group A,n = 21) and inactive HBsAg carriers(Group B,n = 13).Serum cytokines [interferon(IFN)-γ,tumor necrosis factor-α,interleukin(IL)-1b,IL-4,IL-12,IL-10,IL-2,IL-5,IL-8] were analyzed by using flow cytometry.Patients with chronic active disease presented with significantly decreased levels of IFN-γ and IL-10 compared to inac-tive carriers(P = 0.048 and P = 0.008,respectively).In HBeAg-negative chronic active hepatitis B patients,a significant negative correlation of IFN-γ levels with serum hepatitis B viral load was noted(P = 0.021).In conclusion,patients with HBeAg-negative chronic active hepatitis B and HBsAg inactive carriers display a different cytokine profile.Decreased Th1 response observed in patients with chronic active hepatitis B could be implicated in the persistence of virus replication and ongoing progression of liver disease. | Dimitra Dimitropoulou Marina Karakantza Georgios L Theodorou Lydia Leonidou Stelios F Assimakopoulos Athanasia Mouzaki Charalambos A Gogos | 2013 | World Journal of Gastrointestinal Pathophysiology2013，4，1： | 13 |
| 2 | Axial capacity of circularconcrete-filled-tube columns显示文摘 | Georgios G Dennis L | 2004 | Journal ofConstructional Steel Research2004，60，： | 1 |
| 3 | Characterization of Outer Membrane Vesicles from Brucella melitensis and Protection Induced in Mice显示文摘 | Eric Daniel Avila-Calderón Ahidé Lopez-Merino Neeta Jain Humberto Peralta Edgar Oliver López-Villegas Nammalwar Sriranganathan Stephen M. Boyle Sharon Witonsky Araceli Contreras-Rodríguez Georgios Pappas | 2011 | Clinical and Developmental Immunology2011，，： | 1 |
| 4 | Analysis of a mathematical modelof tumor lymphangiogensis 显示文摘 | AVNER F GEORGIOS L | 2005 | Math Models Appl Sci2005，15，： | 1 |
| 5 | Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell显示文摘 | Geogia S Georgios P Evi L and Zissimos M | 2009 | RNA2009，15，： | 1 |
| 6 | Use of culture,PCR analysis,and DNA microarrays for detection of campylobacter jejuni and campylobacter coli from chicken feces显示文摘 | Georgios K Dang D B Marianne L | 2004 | Clinical Microbiology2004，42，9： | 1 |
| 7 | 3D computer-aided recon- struction of the morphology of teeth with malformations显示文摘 | Kleoniki L Georgios M Nikos N | 1997 | Stud Health Technol Inform1997，43，： | 1 |
| 8 | A Flory–Huggins model based on the Hansen solubility parameters显示文摘 | Thomas Lindvig Michael L Michelsen Georgios M Kontogeorgis | 2002 | Fluid Phase Equilibria2002，，1： | 1 |
| 9 | Axial capacity of circular concrete-filled-tube columns显示文摘 | GEORGIOS G DENNIS L | 2004 | Journal of constructional Steel Research2004，60，： | 1 |
| 10 | Distributed simulation of agent-based systems with HLA显示文摘 | MICHAEL L BRIAN L GEORGIOS T | 2007 | ACM Transactions on Modeling and Computer Simulation2007，17，3： | 1 |
| 11 | Development of a sensitive DNA microarray suitable for rapid detection of Campylobacter spp显示文摘 | Georgios K Dang D B Marianne L | 2003 | Molecul Cell Prob2003，17，： | 1 |
| 12 | Galerkin finite element approximations of stochastic elliptic partial differential equations显示文摘 | Ivo Babuska Raúl Tempone E Zouraris Georgios | 2004 | SIAM Journal on Numerical Analysis2004，42，2： | 1 |
| 13 | Bandwith and power-efficient multicarder multiple access显示文摘 | PENG F X SHENG L Z GEORGIOS B G | 2003 | IEEE Trans Communications2003，51，11： | 1 |
| 14 | Space-time frequency-shift keying显示文摘 | Geert L Zhao W Georgios B G | 2004 | IEEE Trans Commun2004，52，3： | 1 |
| 15 | Space-time frequency-shift keying显示文摘 | GEERT L ZHAO Wan-lun GEORGIOS B G | 2004 | IEEE Trans Commun2004，52，3： | 1 |
| 16 | Comparison of the extent and severity of coronary artery disease in patients with acute myoardial infarction with and without microalbuminurla 显示文摘 | Loannis L Athanasios K Georgios L | 2004 | AM J Cardiol2004，94，： | 1 |
| 17 | Comparison of the extent and severity of coronary artery disease in patients with acute myocar- dial infarction with and without microalbuminuria显示文摘 | Loannis L Atanasios k Georgios L | 2004 | Am J Cardiol2004，94，3： | 1 |
| 18 | Molecular imprinting of natural flavonoid antioxidants:Application in solid-phase extraction for the sample pretreatment of natural products prior to HPLC analysis显示文摘 | Georgios T Martina L Veronika S | 2006 | Journal of Separation Science2006，29，15： | 1 |
| 19 | Development of a sensitive DNA microarray suitable for rapid detection of Campylobacter spp显示文摘 | Georgios K Dang D B and Marianne L | 2003 | Molecular and Cellular Probes2003，17，： | 1 |
| 20 | Axial capacity of circular concrete-filled tube columns显示文摘 | GEORGIOS G DENNIS L | 2004 | Journal of Constructional Steel Research2004，60，7： | 1 |
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