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| 1 | Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery显示文摘AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal surgery.METHODS: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after surgery.CONCLUSION: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery. | Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink Jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen | 2008 | World Journal of Gastroenterology2008，14，45： | 4 |
| 2 | Zooprophylaxis as a control strategy for malaria caused by the vector Anopheles arabiensis(Diptera:Culicidae):a systematic review显示文摘Background:Zooprophylaxis is the use of wild or domestic animals,which are not the reservoir host of a given disease,to divert the blood-seeking malaria vectors from human hosts.In this paper,we systematically reviewed zooprophylaxis to assess its efficacy as a malaria control strategy and to evaluate the possible methods of its application.Methods:The electronic databases,PubMed Central^(■),Web of Science,Science direct,and African Journals Online were searched using the key terms:“zooprophylaxis”or“cattle and malaria”,and reports published between January 1995 and March 2016 were considered.Thirty-four reports on zooprophylaxis were retained for the systematic review.Results:It was determined that Anopheles arabiensis is an opportunistic feeder.It has a strong preference for cattle odour when compared to human odour,but feeds on both hosts.Its feeding behaviour depends on the available hosts,varying from endophilic and endophagic to exophilic and exophagic.There are three essential factors for zooprophylaxis to be effective in practice:a zoophilic and exophilic vector,habitat separation between human and host animal quarters,and augmenting zooprophylaxis with insecticide treatment of animals or co-intervention of long-lasting insecticide-treated nets and/or indoor residual spraying.Passive zooprophylaxis can be applied only in malaria vector control if cattle and human dwellings are separated in order to avoid the problem of zoopotentiation.Conclusions:The outcomes of using zooprophylaxis as a malaria control strategy varied across locations.It is therefore advised to conduct a site-specific evaluation of its effectiveness in vector control before implementing zooprophylaxis as the behaviour of Anopheles arabiensis mosquitoes varies across localities and circumstances. | Abebe Asale Luc Duchateau Brecht Devleesschauwer Gerdien Huisman Delenasaw Yewhalaw | 2017 | Infectious Diseases of Poverty2017，6，1： | 1 |
| 3 | A carbohydrate - rich beverage prior to surgery prevents surgery induced immunode pression: A randomized, con- trolled, clinical trial显示文摘 | Melis Gerdien C | 2006 | JPEN2006，1，： | 1 |
| 4 | Intestinal and hepatic metabolism of glutamine and citrulline in humans显示文摘 | Marcel C. G.Van De Poll Gerdien C.Ligthart‐Melis Petra G.Boelens Nicolaas E. P.Deutz Paul A. M.Van Leeuwen Cornelis H. C.Dejong | 2007 | The Journal of Physiology2007，，2： | 1 |
| 5 | Glutamine:recent developments in research on the clinical significance of glutamine显示文摘 | Melis Gerdien C Ter W | | 0，，1： | 1 |
| 6 | Impact of Platform Switching on Peri - Implant Bone Remodeling around Short Implants in the Posterior Region, 1 - Year Results from a Split-Mouth Clinical Trial 显示文摘 | Gerdien T Gerry M Arian V | 2012 | Clinical Implant Dentistry and Related Research2012，，： | 1 |
| 7 | A carbohydrate rich beverage prior to surgery prevents surgery induced immunode pression:A randomized,controlled,clinical trial显示文摘 | Melis Gerdien C | 2006 | JPEN2006，1，： | 1 |
| 8 | Glutamine: recent developments in research on the clinical significance of glutamine 显示文摘 | Melis Gerdien C Ter W | 2004 | Protein and amino acid metabolism2004，7，1： | 1 |
| 9 | Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis 显示文摘 | Alexander J Laarman Gerdien Mijnheer Joe M Mootz | 2012 | The EMBO Journal2012，31，17： | 1 |
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