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| 1 | Mucosal healing and deep remission: What does it mean?显示文摘The use of specific terms under different meanings and varying definitions has always been a source of confusion in science.When we point our efforts towards an evidence based medicine for inflammatory bowel diseases(IBD)the same is true:Terms such as'mucosal healing'or'deep remission'as endpoints in clinical trials or treatment goals in daily patient care may contribute to misconceptions if meanings change over time or definitions are altered.It appears to be useful to first have a look at the development of terms and their definitions,to assess their intrinsic and context-independent problems and then to analyze the different relevance in present-day clinical studies and trials.The purpose of such an attempt would be to gain clearer insights into the true impact of the clinical findings behind the terms.It may also lead to a better defined use of those terms for future studies.The terms'mucosal healing'and'deep remission'have been introduced in recent years as new therapeutic targets in the treatment of IBD patients.Several clinical trials,cohort studies or inception cohorts provided data that the long term disease course is better,when mucosal healing is achieved.However,it is still unclear whether continued or increased therapeutic measures will aid or improve mucosal healing for patients in clinical remission.Clinical trials are under way to answer this question.Attention should be paid to clearly address what levels of IBD activity are looked at.In the present review article authors aim to summarize the current evidence available on mucosal healing and deep remission and try to highlight their value and position in the everyday decision making for gastroenterologists. | Gerhard Rogler Stephan Vavricka Alain Schoepfer Peter L Lakatos | 2013 | World Journal of Gastroenterology2013，19，43： | 4 |
| 2 | Approximation algorithms for scheduling malleable tasks under precedence constraints显示文摘 | RENAUD L DENIS T GERHARD J W | 2002 | International Journal of Foundations of Computer Science2002，13，4： | 1 |
| 3 | Auricular Acupuncture with Laser 显示文摘 | Regina R Gerhard L Frank B | 2013 | Evid Based Complement Ahernat Med2013，2013，98： | 1 |
| 4 | 显示文摘 | Helen L Gerhard J | 1998 | Chest1998，114，： | 1 |
| 5 | Abdominal MR Imaging with a volumetric inierpolated breath hold examination显示文摘 | Neil MR Vivian SL Gerhard L | 1999 | Radiology1999，212，3： | 1 |
| 6 | Advances in chemistry and bioactivity of the genus Uncaria 显示文摘 | GERHARD L | 2004 | Phytother Res2004，18，1： | 1 |
| 7 | A Lateglacial and Holocene organic carbon isotope record of lacustrine palaeoproductivity and climatic change derived from varved lake sediments of Lake Holzmaar, Germany 显示文摘 | Andreas L Gerhard H S Bernd Z | 2003 | Quaternary Science Reviews2003，22，： | 1 |
| 8 | The status,quality,and expansion of the NIH full-length cDNA project:the Mammalian Gene Collection(MGC)显示文摘 | Gerhard D.S Wagner L Feingold E.A Shenmen C.M Grouse L.H Schuler G Klein S.L Old S Rasooly R Good P | | 0，，： | 1 |
| 9 | A switch to high-flux helixonee membranes reverse suppressed interferon-γ production in patients on low-flux dialysis显示文摘 | Gerhard L Daniela N Menachem R | 2003 | Blood Purification2003，21，： | 1 |
| 10 | The influence of the nitrogen content of dip aluminized steel sheet on the growth of the Fe2 Al5 intermetallic compound layer显示文摘 | Gerhard L | 1977 | Practical Metallography1977，14，： | 1 |
| 11 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection ( MGC ) 显示文摘 | Gerhard DS Wagner L Feingold EA | 2004 | Genome Res2004，14，10： | 1 |
| 12 | Side effects of pulsatile GnRH therapy for induction of ovulation显示文摘 | Gerhard MV Wildt L | 2008 | Expert Rev Endocrinol Metab2008，3，5： | 1 |
| 13 | Corrosion of metal bipolar plates for PEM fuel cells: a review显示文摘 | ANTUNES A OLIVEIRA L GERHARD E | 2010 | Inter- national Journal of Hydrogen Energy2010，35，8： | 1 |
| 14 | Effect of thermal exposure on the corrosion properties of an Al-Mg-Sc alloy sheet显示文摘 | Reinhold B Blanka L Gerhard T | 2000 | Materials Science Forum2000，，： | 1 |
| 15 | Socio-economic development and land-use change: Analysis of rural housing land transition in the Transect of the Yangtse River, China 显示文摘 | LONG H L GERHARD K H LI X B | 2007 | Land Use Policy2007，24，1： | 1 |
| 16 | The Necessary Unpleasantness of Literature显示文摘 | Olsen P l Gerhard | 1987 | Samtiden1987，，1： | 1 |
| 17 | Comfort enhancement by an ac- tive vibration reduction system for a flexible railway car body 显示文摘 | Gerhard S Peter L | 2007 | Vehicle System Dynamics2007，45，9： | 1 |
| 18 | Effect of gate dimension on micro injection molded weld line strength with polypropylenc (PP) and high- density polyethylene (HDPE) 显示文摘 | XIE L GERHARD ZIEGMANN | 2010 | The International Journal of Advanced Manufacturing Technology2010，48，： | 1 |
| 19 | Analysis of athermal imaging method for landmine detection, usinginfrared heating of the sand surface显示文摘 | DEANSJ GERHARD J CARTER L J | 2006 | Infrared Physics& Technology2006，48，3： | 1 |
| 20 | Glycosylated compounds from okra inhibit adhesion of helicobacter pylori to human gastric mucosa 显示文摘 | Christian L Fritz T Gerhard F | 2004 | Journal of Agricultural and Food Chemistry2004，52，6： | 1 |
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