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| 1 | Knowledge acquisition, semantic text mining, and security risks in health and biomedical informatics显示文摘Computational techniques have been adopted in medi-cal and biological systems for a long time. There is no doubt that the development and application of computational methods will render great help in better understanding biomedical and biological functions. Large amounts of datasets have been produced by biomedical and biological experiments and simulations. In order for researchers to gain knowledge from origi- nal data, nontrivial transformation is necessary, which is regarded as a critical link in the chain of knowledge acquisition, sharing, and reuse. Challenges that have been encountered include: how to efficiently and effectively represent human knowledge in formal computing models, how to take advantage of semantic text mining techniques rather than traditional syntactic text mining, and how to handle security issues during the knowledge sharing and reuse. This paper summarizes the state-of-the-art in these research directions. We aim to provide readers with an introduction of major computing themes to be applied to the medical and biological research. | J Harold Pardue William T Gerthoffer | 2012 | World Journal of Biological Chemistry2012，3，2： | 2 |
| 2 | Signal transduction in smooth muscle invited review:Focal adhesion and small heat shock proteins in the regulation of actin remodeling and contractility in smooth muscle显示文摘 | Gerthoffer WT Gunst SJ | 2001 | J Appl Physiol2001，91，2： | 1 |
| 3 | MAPK regulation of gene expression in airway smooth muscle显示文摘 | Gerthoffer W T Singer C A | 2003 | Respir Physiol Neurobio2003，137，23： | 1 |
| 4 | Mechanisms of vascular smooth muscle cell migration显示文摘 | Gerthoffer WT | 2007 | Circ Res2007，100，3： | 1 |
| 5 | Mechanisms of vascular smooth muscle cell migration显示文摘 | Gerthoffer W T | 2007 | Circ Res2007，100，5： | 1 |
| 6 | Airway smooth muscle in bronchial tone,inflammation,and remodeling:basic knowledge to clinical relevance显示文摘 | Panettieri RA Jr Kotlikoff MI Gerthoffer WT | | 0，，： | 1 |
| 7 | Small heat shock proteins in smooth muscle显示文摘 | Salinthone S Tyagi M Gerthoffer WT | 2008 | Pharma Ther2008，119，： | 1 |
| 8 | Moving away from the midline: new de- velopments for Slit and Robo显示文摘 | William T Gerthoffer | 2008 | Proceedings of The American Thoracic Society2008，5，： | 1 |
| 9 | 1M21p44 MAP kinase acti- vation is localized to caveolae-free membrane domains in airway smooth muscle显示文摘 | Gosens R Dueck G Gerthoffer WT | 2007 | Am J Physiol Lung Cell Mol Physio12007，292，5： | 1 |
| 10 | PI 3 - kinases and Src kinases regulate spreading and migration of cultured VSMCs显示文摘 | Yamboliev IA Chen J Gerthoffer WT | 2001 | 2001,281(2) :709 -7182001，281，2： | 1 |
| 11 | Mitogen-activated protein kinases regulate cytokine gene expoession in human airway myocytes 显示文摘 | Hedges JC Singer CA Gerthoffer WT | 2000 | Am J Respir Cell Mol Biol2000，23，1： | 1 |
| 12 | Mechanisms of vascular smooth muscle cell migration显示文摘 | Gerthoffer WT | 2007 | Circ Res2007，100，5： | 1 |
| 13 | p42/p44 MAP kinase activation is localized to caveolae-free membrane domains in airway smooth muscle显示文摘 | Gosens R Dueck G Gerthoffer WT | 2007 | Am J Physiol Lung Cell Mol Physiol2007，292，： | 1 |
| 14 | Small heat shock proteins in smooth muscle显示文摘 | Salinthone S Tyagi M Gerthoffer WT | 2008 | Pharmacol Ther2008，119，1： | 1 |
| 15 | Mechanisms of vascular smooth muscle cell mi- gration显示文摘 | Gerthoffer WT | 2007 | Circ Res2007，100，5： | 1 |
| 16 | Airway smooth muscle in bronchial tone, inflamma- tion, and remodeling: basic knowledge to clinical rele vance 显示文摘 | Panettieri RA Jr Kotlikoff MI Gerthoffer WT | 2008 | Am J Respir Crit Care Med2008，177，3： | 1 |
| 17 | Invited review : focal adhesionand small heat shock proteins in the regulation of actin re-modeling and contractility in smooth muscle 显示文摘 | Gerthoffer WT Gunst SJ | 2001 | J ApplPhysiol2001，91，2： | 1 |
| 18 | Small heat shock proteins in smooth muscle 显示文摘 | Salinthone S Tyaqi M Gerthoffer WT | 2008 | Pharmaco! Ther2008，119，1： | 1 |
| 19 | Small heat shock proteins in smooth muscle 显示文摘 | Salinthone S Tyagi M Gerthoffer WT | 2008 | Pharmacol Ther2008，119，1： | 1 |
| 20 | Myocardin is sufficient for asmooth muscle-like contractile phenotype 显示文摘 | LongX Bell RD Gerthoffer WT et at | 2008 | Arterioscler ThrombVase Biol2008，28，8： | 1 |
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