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| 1 | Reversed-phase fused-core HPLC modeling of peptides显示文摘Different fused-core stationary phase chemistries(C18,Amide,Phenyl-hexyl and Peptide ES-C18) were used for the analysis of 21 structurally representative model peptides.In addition,the effects of the mobile phase composition(ACN or MeOH as organic modifier;formic acid or acetic acid,as acidifying component) on the column selectivity,peak shape and overall chromatographic performance were evaluated.The RP-amide column,combined with a formic acid-acetonitrile based gradient system,performed as best.A peptide reversed-phase retention model is proposed,consisting of 5 variables:log SumAA,log Sv,clog P,log nHDon and log nHAcc.Quantitative structure-retention relationship(QSRR) models were constructed for 16 different chromatographic systems.The accuracy of this peptide retention model was demonstrated by the comparison between predicted and experimentally obtained retention times,explaining on average 86% of the variability.Moreover,using an external set of 5 validation peptides,the predictive power of the model was also demonstrated.This peptide retention model includes the novel in-silico calculated amino acid descriptor,AA,which was calculated from log P,3D-MoRSE,RDF and WHIM descriptors. | Matthias D'Hondt Bert Gevaert Sofie Stalmans Sylvia Van Dorpe Evelien Wynendaele Kathelijne Peremans Christian Burvenich Bart De Spiegeleer | 2013 | Journal of Pharmaceutical Analysis2013，3，2： | 3 |
| 2 | 老龄小鼠模型内皮细胞衰老导致射血分数保留的心力衰竭显示文摘由于全球老龄化,射血分数保留的心力衰竭(heart failure with preserved ejection fraction,HFpEF)发生率持续上升。虽然HFpEF的病理生理机制仍然不完全清楚,但通常认为内皮炎症发挥了核心作用。细胞衰老是一种与老化和炎症有关的细胞生长停滞过程。Gevaert等使用加速老化的小鼠(senescence-accelerated mice,SAM)模型探究细胞衰老在HFpEF发生发展中的作用。 | 刘莉 叶鹏 Gevaert AB Shakeri H Leloup AJ Van Hove CE De Meyer GRY Vrints CJ Lemmens K Van Craenenbroeck EM | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 3 | Wound healing of the nasal and paranasal mucosa: a review显示文摘 | WATELET J B BACHERT C GEVAERT P | 2002 | Am J Rhinol2002，16，： | 1 |
| 4 | Would healing of the nasal and paranasal mucosa: a review 显示文摘 | Watelet JB Bachet C Gevaert P | 2002 | Am J Rhi- hal2002，16，2： | 1 |
| 5 | Secretion of TGF-beta l,TGF-beta2,EGF and PDGF into nasal fluid after sinus surgery显示文摘 | Watelet JB Gevaert P Bachert C | 2002 | Eur Arch Otorhinolaryngol2002，259，5： | 1 |
| 6 | Secretion of TGF-betal,TGF-beta2,EGF and PDGF into nasal fluid after sinus surgery显示文摘 | Watelet JB Gevaert P Bachert C | | 0，，05： | 1 |
| 7 | Discriminating between bilayer and bulk heterojunction polymer: Fullerene solar cells using the external quantum efficiency显示文摘 | Gevaerts V S Koster L J A Wienk M M | 2011 | ACS Appl Mater Interfaces2011，3，9： | 1 |
| 8 | Nasal polyps:from cytokines growth显示文摘 | Bachert C Gevaert P Holtappels G | 2000 | Am J Rhinol2000，14，3： | 1 |
| 9 | The expression,processing and localization of polymorphic membrane proteins in Chlamydia pneumoniae strain CWL029显示文摘 | Vandahl BB Pedersen AS Gevaert K | 2002 | BMC Microbiol2002，2，： | 1 |
| 10 | Protein identification based on matrix assisted laser desorption/ionization-post source decay-mass spectrometry显示文摘 | GEVAERT K DEMOL H MARTENS L | 2001 | Electrophoresis2001，22，9： | 1 |
| 11 | Protein identification methods in proteomics显示文摘 | Gevaert K Vandekerekhove J | 2000 | Electrophoresis2000，21，： | 1 |
| 12 | Differentiation of chronic sinus diseases by measurement of inflammatory mediators显示文摘 | Van Zele T Claeys S Gevaert P | 2006 | Allergy2006，61，： | 1 |
| 13 | Polymers for colon specific drug delivery显示文摘 | Schacht Etienne Gevaert An Kenawy El Refaie | 1996 | J Controlled Release1996，，39： | 1 |
| 14 | Non-invasive diagnosis of endometriosis based on a combined analysis of six plasma biomarkers 显示文摘 | Mihalyi A Gevaert C Kyama M | 2010 | Human Reproduction2010，3，25： | 1 |
| 15 | Nasal polyposis: from cytokines to growth显示文摘 | Baehert C Gevaert P Holtappels G | 2000 | Am J Rhinol2000，14，5： | 1 |
| 16 | Rac/Cdc42 and p65PAK regulate the microtubule-destabilizing protein Stathmin through phosphorylation at serine 16显示文摘 | Daub H Gevaert K Vandekerckhove J | 2001 | J Biol Chem2001，276，3： | 1 |
| 17 | Pathogenesis of chronic rhinosinusitis: In- flammation显示文摘 | VAN CROMBRUGGEN K ZHANG N GEVAERT P | 2011 | J Allergy Clin Immunol2011，128，： | 1 |
| 18 | The unsolved enigmas of leukemia inhibitory factor 显示文摘 | Metcalf D Bachert C Gevaert P | 2003 | Stem cells2003，21，： | 1 |
| 19 | Stable isotopic labeling in proteomics 显示文摘 | GEVAERT K IMPENS F GHESQUIIRE B | 2008 | J Pro- teomies2008，8，2324： | 1 |
| 20 | Evaluating marine ecosystem health: Case studies of indicators using direct observations and modelling methods显示文摘 | I. Rombouts G. Beaugrand L.F. Artigas J.-C. Dauvin F. Gevaert E. Goberville D. Kopp S. Lefebvre C. Luczak N. Spilmont M. Travers-Trolet M.C. Villanueva R.R. Kirby | 2013 | Ecological Indicators2013，，： | 1 |
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