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| 1 | Cigarette smoking, dietary habits and genetic polymorphisms in GSTT1, GSTM1 and CYP1A1 metabolic genes: A case-control study in oncohematological diseases显示文摘AIM To analyze the association between oncohematological diseases and GSTT1 /GSTM1 /CYP1A1 polymorphisms, dietary habits and smoking, in an argentine hospitalbased case-control study.METHODS This hospital-based case-control study involved 125 patients with oncohematological diseases and 310 control subjects. A questionnaire was used to obtain sociodemographic data and information about habits. Blood samples were collected, and DNA was extracted using salting out methods. Deletions in GSTT1 and GSTM1 (null genotypes) were addressed by PCR. CYP1A1 MspI polymorphism was detected by PCR-RFLP. Odds ratio(OR) and 95%CI were calculated to estimate the association between each variable studied and oncohematological disease.RESULTS Women showed lower risk of disease compared to men(OR 0.52, 95%CI: 0.34-0.82, P = 0.003). Higher levels of education(> 12 years) were significantly associated with an increased risk, compared to complete primary school or less(OR 3.68, 95%CI: 1.82-7.40, P < 0.001 adjusted for age and sex). With respect to tobacco, none of the smoking categories showed association with oncohematological diseases. Regarding dietary habits, consumption of grilled/barbecued meat 3 or more times per month showed significant association with an increased risk of disease(OR 1.72, 95%CI: 1.08-2.75, P = 0.02). Daily consumption of coffee also was associated with an increased risk(OR 1.77, 95%CI: 1.03-3.03, P = 0.03). Results for GSTT1, GSTM1 and CYP1A1 polymorphisms showed no significant association with oncohematological diseases. When analyzing the interaction between polymorphisms and tobacco smoking or dietary habits, no statistically significant associations that modify disease risk were found. CONCLUSION We reported an increased risk of oncohematological diseases associated with meat and coffee intake. We did not find significant associations between genetic polymorphisms and blood cancer. | María Belén Cerliani Walter Pavicic Juan Antonio Gili Graciela Klein Silvia Saba Silvina Richard | 2016 | World Journal of Clinical Oncology2016，7，5： | 1 |
| 2 | The impact of biofuels on engine oil performance显示文摘 | GILI F IGARTUA A LUTHER R | 2011 | Lubric Sci2011，23，7： | 1 |
| 3 | Holmium la-ser enucleation of the prostate (HoLEP) combined withtransurethral tissue morcellation: an update on the ear-ly clinical experience 显示文摘 | Giliing P J Kennett K Das A K | 1998 | J Endourol1998，12，5： | 1 |
| 4 | Using Global Positioning System techniques in landslide monitoring 显示文摘 | Gili J A Corominas J Rius J | 2000 | Eng Geol2000，55，3： | 1 |
| 5 | The impact of biofuels on engine oil performance显示文摘 | Gili F Igartua A Luther R | 2011 | Lubrication Science2011，23，31： | 1 |
| 6 | A structural analysis of the first Cardington test显示文摘 | USMANI A S ROTTER J M | 2001 | Journal of Constructional Steel Research2001，57，： | 1 |
| 7 | Comorbidity between com- mon mental disorders and chronic somatic diseases in primary care pa- tients 显示文摘 | Gili M Comas A Garcia-Garcfa M | 2010 | General Hospital Psychiatry2010，32，3： | 1 |
| 8 | Effect of coronary angioplasty on precordial QT dispersion显示文摘 | Yunus A Gilis AM Traboulsi M | 1997 | Am J Cardiol1997，79，： | 1 |
| 9 | Comorbidity betweencommon mental disorders and chronic somatic diseases in primarycare patiental显示文摘 | GiLi M Comas A Garcia-Garcia M | 2010 | Gen Hosp Psychiatry2010，32，： | 1 |
| 10 | Repair welding of cracked steam turbine blades usingaustenitic and mar- tensitic stainless - steel consumables显示文摘 | A K Bhaduri T P S GilI S K Albert | 2001 | Nuclear Engi- neering and Design2001，，206： | 1 |
| 11 | Microstructural deformation mechanisms of unsaturated granular soils显示文摘 | GILI J A ALONSO E E | 2002 | International Journal for Numerical and Analytical Methods in Geomechanics2002，26，43： | 1 |
| 12 | House in Alvalade 2G International显示文摘 | Gili M Puente M Puyuelo A | | 0，，28： | 1 |
| 13 | Revision of carcinomas in paranasal sinuses显示文摘 | Gras Cabrerizo JR Sarandeses Garcia A Montserrat I Gili JR | 2007 | Acta Otorrinolaringol Esp2007，58，6： | 1 |
| 14 | A genetic algorithm for the post take-off ma- noeuvre optimization显示文摘 | E Busto P A Gili | 1997 | AIAA- 1997-3587-9551997，，： | 1 |
| 15 | The impact of biofuels on engine oil performance 显示文摘 | GILI F IGARTUA A LUTHER R | 2011 | Lubrication Science2011，23，7： | 1 |
| 16 | Colometric method for determination of sugars and related substance显示文摘 | DUBOIS M GILIES K A HAMILTON J K | 1996 | Analytical Chemistry1996，28，： | 1 |
| 17 | Using Global Positioning System techniques in landslide monitoring显示文摘 | Gili J A Corominas J Rius J | 2000 | Engineering Geology2000，55，： | 1 |
| 18 | Establishing a competence profile for the role of student-centred teachers in higher education in Belgium显示文摘 | Gilis A Clement M Laga L | 2008 | Research in Higher Education2008，49，6： | 1 |
| 19 | Evaluation of tannin biopolymer as a coagulant aid for coagulation of colloidal partic显示文摘 | MAHMUT O SEN GILI A | | 0，，： | 1 |
| 20 | TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts显示文摘 | Caraci F Gili E Calafiore M Fail a M La Rosa C Crimi N | 2008 | Pharmacol Res2008，57，4： | 1 |
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