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| 1 | Liver Transplantation in Alcoholic Patients: Impact of an Alcohol Addiction Unit Within a Liver Transplant Center显示文摘 | Giovanni Addolorato Antonio Mirijello Lorenzo Leggio Anna Ferrulli Cristina D’Angelo Gabriele Vassallo Anthony Cossari Giovanni Gasbarrini Raffaele Landolfi Salvatore Agnes Antonio Gasbarrini | 2013 | Alcohol Clin Exp Res2013，，9： | 2 |
| 2 | Acute alcohol intoxication显示文摘 | Luisa Vonghia Lorenzo Leggio Anna Ferrulli Marco Bertini Giovanni Gasbarrini Giovanni Addolorato | 2008 | European Journal of Internal Medicine2008，，8： | 1 |
| 3 | Gender Affects Reperfusion Injury in Rat Liver显示文摘 | Antonio Gasbarrini Giovanni Addolorato Cristiana Di Campli Mara Simoncini Salvatore Montemagno Marco Castagneto Cristiano Padalino Paolo Pola Giovanni Gasbarrini | 2001 | Digestive Diseases and Sciences2001，，6： | 1 |
| 4 | Reverse time-dependent effect of alphafetoprotein and disease control on survival of patients with Barcelona Clinic Liver Cancer stage C hepatocellular carcinoma显示文摘AIM To characterize the survival of cirrhotic patients with Barcelona Clinic Liver Cancer(BCLC) stage C hepatocellular carcinoma(HCC) and to ascertain the factors predicting the achievement of disease control(DC).METHODS The cirrhotic patients with BCLC stage C HCC evaluated by the Hepatocatt multidisciplinary group were subjected to the investigation. Demographic, clinical and tumor features, along with the best tumor response and overall survival were recorded. RESULTS One hundred and ten BCLC stage C patients were included in the analysis; the median overall survival was 13.4 mo(95%CI: 10.6-17.0). Only alphafetoprotein(AFP) serum level > 200 ng/m L and DC could independently predict survival but in a time dependent manner, the former was significantly associated with increased risk of mortality within the first 6 mo of follow-up(HR = 5.073, 95%CI: 2.159-11.916, P = 0.0002), whereas the latter showed a protective effect against death after one year(HR = 0.110, 95%CI: 0.038-0.314, P < 0.0001). Only patients showing microvascular invasion and/or extrahepatic spread recorded lower chances of achieving DC(OR = 0.263, 95%CI: 0.111-0.622, P = 0.002).CONCLUSION The BCLC stage C HCC includes a wide heterogeneous group of cirrhotic patients suitable for potentially curative treatments. The reverse and time dependent effect of AFP serum level and DC on patients' survival confers them as useful predictive tools for treatment management and clinical decisions. | Francesca Romana Ponziani Irene Spinelli Emanuele Rinninella Lucia Cerrito Antonio Saviano Alfonso Wolfango Avolio Michele Basso Luca Miele Laura Riccardi Maria Assunta Zocco Brigida Eleonora Annicchiarico Matteo Garcovich Marco Biolato Giuseppe Marrone Anna Maria De Gaetano Roberto Iezzi Felice Giuliante Fabio Maria Vecchio Salvatore Agnes Giovanni Addolorato Massimo Siciliano Gian Lodovico Rapaccini Antonio Grieco Antonio Gasbarrini Maurizio Pompili | 2017 | World Journal of Hepatology2017，9，36： | 1 |
| 5 | Acute alcohol intoxication显示文摘 | Luisa Vonghia Lorenzo Leggio Anna Ferrulli Marco Bertini Giovanni Gasbarrini Giovanni Addolorato | 2008 | European Journal of Internal Medicine2008，，8： | 1 |
| 6 | Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study显示文摘 | Giovanni Addolorato Lorenzo Leggio Anna Ferrulli Silvia Cardone Luisa Vonghia Antonio Mirijello Ludovico Abenavoli Cristina D’Angelo Fabio Caputo Antonella Zambon Paul S Haber Giovanni Gasbarrini | 2007 | The Lancet2007，，9603： | 1 |
| 7 | Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study显示文摘 | Giovanni Addolorato Lorenzo Leggio Anna Ferrulli Silvia Cardone Luisa Vonghia Antonio Mirijello Ludovico Abenavoli Cristina D’Angelo Fabio Caputo Antonella Zambon Paul S Haber Giovanni Gasbarrini | 2007 | 2007 (9603)2007，，9603： | 1 |
| 8 | Association between migraine and celiac disease: results from a preliminary case-control and therapeutic study显示文摘 | Maurizio Gabrielli Filippo Cremonini Giuseppe Fiore Giovanni Addolorato Cristiano Padalino Marcello Candelli Maria Elena De Leo Luca Santarelli Mario Giacovazzo Antonio Gasbarrini Paolo Pola Antonio Gasbarrini | 2003 | The American Journal of Gastroenterology2003，，3： | 1 |
| 9 | Increased Serum High-density Lipoprotein-Cholesterol Concentration in Celiac Disease After Gluten-free Diet Treatment Correlates With Body Fat Stores显示文摘 | Esmeralda Capristo Noemi Malandrino Sara Farnetti Geltrude Mingrone Lorenzo Leggio Giovanni Addolorato Giovanni Gasbarrini | 2009 | Journal of Clinical Gastroenterology2009，，10： | 1 |
| 10 | Pharmacotherapy of acute alcoholic hepatitis in clinical practice显示文摘Severe alcoholic hepatitis(AH)is an acute form of alcohol induced liver disease with a poor prognosis that is seen in the patients who consume large quantities of alcohol.The diagnosis of AH is based on the appropriate alcohol intake history and is supported with clinical and histological features,and several scoring systems.Glucocorticoids are the mainstay for treating severe AH with pentoxifylline used as an alternative to steroids in addition to total alcohol abstinence.Liver transplantation is a possible therapeutic option for severe AH.Among the anti-craving medications able to improve abstinence rate,baclofen seems to be effective and safe in the alcoholic patients affected by severe liver damage. | Ludovico Abenavoli Natasa Milic Samir Rouabhia Giovanni Addolorato | 2014 | World Journal of Gastroenterology2014，20，9： | 0 |
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