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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | MicroRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | Henke JI Goergen D Zheng J | 2008 | Embo J2008，27，24： | 1 |
| 3 | microRNA -122 stimulatestranslation of hepatitis C virus RNA 显示文摘 | Henke JI* Goergen D Zheng JF? | 2008 | EMBO J2008，27，24： | 1 |
| 4 | microRNA-122 stimulates translation of hepalitis C virus RNA显示文摘 | Henk JI Goergen D Zheng J | 2008 | EMBO J2008，27，24： | 1 |
| 5 | Multidetector CT dose: clinical practice improvement strategies from a success- ful optimization program 显示文摘 | Wallace AB Goergen SK Schick D | 2010 | J Am Coil Radiol2010，7，8： | 1 |
| 6 | MicroRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | HENKE JI GOERGEN D ZHENG J | 2008 | EMBO J2008，27，24： | 1 |
| 7 | microRNA-122 stimulates translation of hepatitis C virus RNA 显示文摘 | Henke JI Goergen D Zheng J Song Y Schuttler CG Fehr C | 2008 | EMBO J2008，27，24： | 1 |
| 8 | Clinical,radiographic and pathologic abnormalities in calcium pyrophosphate dehydrate deposition disease (CPPD):pseudogout显示文摘 | Resnick D Niwayama G Goergen TG | 1977 | Diagn Radiol1977，122，1： | 1 |
| 9 | microRNA-122 stimulates translation of hepatitis C virus RNA 显示文摘 | Henke J I Goergen D Zheng J Song Y | 2008 | EMBO J2008，27，： | 1 |
| 10 | 2009, New records of invasive insects (Hemiptera: Stemorrhyneha) in Southeast Asia and West Africa 显示文摘 | MuniappanR Shepard B M Watson G W Carner G R Rauf A Sartiami D Hidayat P Afun J V K Goergen G Ziaur Rah- man A K M | 2009 | Journal of Agricultural and Urban Entomology2009，26，： | 1 |
| 11 | Perimesencephalic hemorrhage: negative angiography and favourable prognosis显示文摘 | Goergen SK Barrie D Sacharias N | 1993 | Australas Radiol1993，37，： | 1 |
| 12 | microRNA - 122 stimulates translation of hepatitis C virus RNA 显示文摘 | Henke J I Goergen D Zheng J Song Y SchiJttler C G Fehr C Jiinemann C Niepmann M | 2008 | TheEMBOJ2008，27，24： | 1 |
| 13 | microRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | Henke JI Goergen D Zheng J | 2008 | EMBO J2008，27，24： | 1 |
| 14 | microRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | HENKE J I GOERGEN D ZHENG J | | 0，，24： | 1 |
| 15 | Evaluation of acetabular anteversion follow- ing total hip arthroplasty : necessity of proper centering 显示文摘 | Goergen TG Resnick D | 1975 | Br J Radi- ol1975，48，： | 1 |
| 16 | microRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | HENKE J GOERGEN D ZHENG J | 2008 | Nature2008，27，24： | 1 |
| 17 | microRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | HENKE J I GOERGEN D ZHENG J | | 0，，24： | 1 |
| 18 | blicroRNA - 122 stimulates translation of hepatitis C virus RNA显示文摘 | HENKE J I GOERGEN D ZHENG J | 2008 | EMBO J2008，27，24： | 1 |
| 19 | mieroRNA-122 stimulates translation of hepatitis C virus RNA显示文摘 | Henke J I Goergen D Zheng J | 2008 | EMBO J2008，27，24： | 1 |
| 20 | Comparison of radiographic abnormalities of the Sacroiliac joint in degenerative disease and ankylosing spondylitis 显示文摘 | Resnick D Niwayama G Goergen TG | 1977 | A JR Am J Roentgenol1977，128，2： | 1 |
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