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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Prostate cancer upgrading or downgrading of biopsy Gleason scores at radical prostatectomy:prediction of'regression to the mean'using routine clinical features with correlating biochemical relapse rates显示文摘Recommendations for managing clinically localized prostate cancer are structured around clinical risk criteria,with prostate biopsy(PB)Gleason score(GS)being the most important factor.Biopsy to radical prostatectomy(RP)specimen upgrading/downgrading is welldescribed,and is often the ratio nale for costly imaging or genomic studies.We prese nt simple,no-cost an a lyses of clinical parametersto predict which GS 6 and GS 8 patients will change to GS 7 at prostatectomy.From May 2006 to December 2012,1590 patientsunderwent robot-assisted radical prostatectomy(RARP).After exclusions,we identified a GS 6 cohort of 374 patients and a GS 8cohort of 91 patients.During this era,>1000 additional patients were enrolled in an active surveillanee(AS)program.For GS 6,265(70.9%)of 374 patients were upgraded,and the cohort included 183(48.9%)patients eligible for AS by the Prostate Cancer ResearchInternational Active Surveillance Study(PRIAS)standards,of which 57.9%were upgraded.PB features that predicted a>90%chanceof upgrading included≥7 cores positive,maximum foci length≥8 mm in any core,and total tumor involvement≥30%.For GS 8,downgrading occurred in 46(50.5%),which was significantly higher for single core versus multiple cores(80.4%vs 19.6%,P=0.011).Biochemical recurre nee(BCR)occurred in 3.4%of GS 6 upgraded versus 0%non upgraded,and in GS 8,19.6%downgraded versus42.2%nondown graded.In coun seling men with clin ically localized prostate can cer,the odds of GS cha nge should be presented,andcertain men with high-volume GS 6 or low-volume GS 8 can be counseled with GS 7-based recommendations. | Muammer Altok Patricia Troncoso Mary F Achim Surena F Matin Graciela N Gonzalez John W Davis | 2019 | Asian Journal of Andrology2019，21，6： | 4 |
| 3 | Acid activation of a palygorskite with HCl:development of physico-chemical,textural and surface properties显示文摘 | BARRIOS M S GONZALEZ F VICENTE-RODRIGUEZ M A | 1995 | Appl Clay Sci1995，30，10： | 2 |
| 4 | The prolactin family hormones regulate vascular tone through NO and prostacyclin production in isolated rat aortic rings显示文摘目的: 催乳激素家庭荷尔蒙包括生长荷尔蒙,胎盘的促黄体激素和催乳激素,它能调整 angiogenesis 经由没有并且前列腺素。然而,他们脉管的音调上的效果充分没被理解。这研究的目的是在老鼠上评估催乳激素家庭荷尔蒙的效果脉管的在 vitro 的音调。 | Carmen GONZALEZ Hector ROSAS-HERNANDEZ Brenda JURADO-MANZANO Manuel Alejandro RAMIREZ-LEE Samuel SALAZAR-GARClA Pedro Pablo MARTINEZ-CUEVAS Aida Jimena VELARDE-SALCEDO Humberto MORALES- LOREDO Ricardo ESPINOSA-TANGUMA Syed F ALl Rafael RUBIO | 2015 | Acta Pharmacologica Sinica2015，36，5： | 2 |
| 5 | Nitric-oxide-directed synaptie remodeling in the adult mamml CNS 显示文摘 | Sunieo C R Portillo F Gonzalez Forero D | 2005 | Neuroscience2005，25，6： | 1 |
| 6 | Autoregulation of cerebral blood flow in orthostatic hypotension after spinal cord injury显示文摘 | Chang JY Banovac K | 1991 | Paraplegia1991，29，1： | 1 |
| 7 | Curing process of phenol urea - formaldehyde - tannin (PUFF) adhesives -Kinetic studies by DSC and DMA显示文摘 | Vazquez G Lopez - Suevos F Gonzalez - Alvarez J | 2005 | Journal of thermal analy- sis and calorimetry2005，82，1： | 1 |
| 8 | Incidence and c]inical effects of intra--abdominal hypertension in critically ill patients显示文摘 | ViDL MG P uiz Weisser J Gonzalez F | 2008 | Critical care medicine2008，56，6： | 1 |
| 9 | Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome显示文摘 | Almazan F Gonzalez J M Penzes Z | 2000 | Proc Natl Acad Sci U S A2000，97，10： | 1 |
| 10 | Pillared clays: Catalytic evaluation in heavy oil cracking using a micreactivity test显示文摘 | Gonzalez F Pesquera Benito I | 1999 | Applied Catalysis A:General1999，181，： | 1 |
| 11 | Ammoxidized Kraft lignin as a slow-release fertilizer tested on sorghum vulgare显示文摘 | Ramirez F Gonzalez V Crespo M | 1997 | Bioresource Technology1997，，61： | 1 |
| 12 | The effect of grain size on the wear properties of electrodeposited nanocrystalline nickel coatings显示文摘 | Jeong D H Gonzalez F Palumbo G | 2001 | Seripta Mater2001，44，3： | 1 |
| 13 | Nasal chondromesenchymal hamartoma in children: report of 2 cases with review of the literature显示文摘 | Hsueh C Hsueh S GonzalezCrussi F | 2001 | Arch Pathol Lab Med2001，125，3： | 1 |
| 14 | Harnessing dielectric forces for separations of cells, fine particles and macromolecules 显示文摘 | Gonzalez C F Remcho V T | 2005 | J Chromatogr A2005，1079，12： | 1 |
| 15 | Combustion optimisation of biomass residue pellets for domestic heating with a mural boiler显示文摘 | GONZALEZ J F MGONZALEZ-GARCIA C RAMIRO A | 2004 | Biomass and Bioenergy2004，27，： | 1 |
| 16 | Design of metal interconnects for stretchable electronic circuits 显示文摘 | GONZALEZ M AXISA F BULCKE M V | 2008 | Microelectronics Reliability2008，48，6： | 1 |
| 17 | Support effects on the performance of Pt/CeO2 and Pt/ Al2O3 catalysts for the dry reforming of methane 显示文摘 | Gonzalez F Gomez- Cortes A Arenas -Alatorre F | 1998 | Appl Catal A1998，3，： | 1 |
| 18 | Role of gene knockout and transgenic mice in the study of xenobiotic metabolism 显示文摘 | Gonzalez F J | 2003 | Drug Metab Rev2003，35，4： | 1 |
| 19 | Forensic analysis of buildings affected by mining subsidence 显示文摘 | GAYARRE F ALVAREZ-FERNANDEZ M I GONZALEZ NICIEZA C | 2010 | Engineering Failure Analysis2010，17，1： | 1 |
| 20 | Oesophageal tone in patients with achalasia 显示文摘 | Gonzalez M Mearin F Vasconez C | 1997 | Gut1997，41，3： | 1 |
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