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| 1 | Endoscopy-based management decreases the risk of postoperative recurrences in Crohn's disease显示文摘AIM: To investigate whether an endoscopy-based management could prevent the long-term risk of postoperative recurrence.METHODS: From the pathology department database, we retrospectively retrieved the data of all the patients operated on for Crohn's disease(CD) in our center(1986-2015). Endoscopy-based management was defined as systematic postoperative colonoscopy(median time after surgery = 9.5 mo) in patients with no clinical postoperative recurrence at the time of endoscopy. RESULTS: From 205 patients who underwent surgery, 161 patients(follow-up > 6 mo) were included. Endoscopic postoperative recurrence occurred in 67.6%, 79.7%, and 95.5% of the patients, respectively 5, 10 and 20 years after surgery. The rate of clinical postoperative recurrence was 61.4%, 75.9%, and 92.5% at 5, 10 and 20 years, respectively. The rate of surgical postoperative recurrence was 19.0%, 38.9% and 64.7%, respectively, 5, 10 and 20 years after surgery. In multivariate analysis, previous intestinal resection, prior exposure to anti-TNF therapy before surgery, and fistulizing phenotype(B3) were postoperative risk factors. Previous perianal abscess/fistula(other perianal lesions excluded), were predictive of only symptomatic recurrence. In multivariate analysis, an endoscopy-based management(n = 49/161) prevented clinical(HR = 0.4, 95%CI: 0.25-0.66, P < 0.001) and surgical postoperative recurrence(HR = 0.30, 95%CI: 0.13-0.70, P = 0.006).CONCLUSION: Endoscopy-based management should be recommended in all CD patients within the first year after surgery as it highly decreases the long-term risk of clinical recurrence and reoperation. | Anne-Laure Boucher Bruno Pereira Stéphanie Decousus Marion Goutte Felix Goutorbe Anne Dubois Johan Gagniere Corinne Borderon Juliette Joubert Denis Pezet Michel Dapoigny Pierre J Déchelotte Gilles Bommelaer Anthony Buisson | 2016 | World Journal of Gastroenterology2016，22，21： | 3 |
| 2 | On clustering FMRI time series显示文摘 | Goutte C Toft P Rostrup E | 1999 | Neuroimage1999，9，3： | 1 |
| 3 | Feature-space clus- tering for fMRI Meta-analysis 显示文摘 | GOUTTE C HANSEN L K LIPTROT M G | 2001 | Human Brain Mapping2001，13，3： | 1 |
| 4 | Faecal calprotectin and magnetic resonance imaging in detecting Crohn's disease endoscopic postoperative recurrence显示文摘AIM To assess magnetic resonance imaging(MRI) and faecal calprotectin to detect endoscopic postoperative recurrence in patients with Crohn's disease(CD).METHODS From two tertiary centers, all patients with CD who underwent ileocolonic resection were consecutively and prospectively included. All the patients underwent MRI and endoscopy within the first year after surgery or after the restoration of intestinal continuity [median = 6 mo(5.0-9.3)]. The stools were collected the day before the colonoscopy to evaluate faecal calprotectin level. Endoscopic postoperative recurrence(POR) was defined as Rutgeerts' index ≥ i2b. The MRI was analyzed independently by two radiologists blinded from clinical data.RESULTS Apparent diffusion coefficient(ADC) was lower in patients with endoscopic POR compared to those with no recurrence(2.03 ± 0.32 vs 2.27 ± 0.38 × 10^(-3) mm^2/s, P = 0.032). Clermont score(10.4 ± 5.8 vs 7.4 ± 4.5, P = 0.038) and relative contrast enhancement(RCE)(129.4% ± 62.8% vs 76.4% ± 32.6%, P = 0.007) were significantly associated with endoscopic POR contrary to the magnetic resonance index of activity(Ma RIA)(7.3 ± 4.5 vs 4.8 ± 3.7; P = 0.15) and MR scoring system(P = 0.056). ADC < 2.35 × 10^(-3) mm^2/s [sensitivity = 0.85, specificity = 0.65, positive predictive value(PPV) = 0.85, negative predictive value(NPV) = 0.65] and RCE > 100%(sensitivity = 0.75, specificity = 0.81, PPV = 0.75, NPV = 0.81) were the best cutoff values to identify endoscopic POR. Clermont score > 6.4(sensitivity = 0.61, specificity = 0.82, PPV = 0.73, NPV = 0.74), Ma RIA > 3.76(sensitivity = 0.61, specificity = 0.82, PPV = 0.73, NPV = 0.74) and a MR scoring system ≥ MR1(sensitivity = 0.54, specificity = 0.82, PPV = 0.70, and NPV = 0.70) demonstrated interesting performances to detect endoscopic POR. Faecal calprotectin values were significantly higher in patients with endoscopic POR(114 ± 54.5 μg/g vs 354.8 ± 432.5 μg/g; P = 0.0075). Faecal calprotectin > 100 μg/g demonstrated high performances to detect endoscopic POR(sensitivity = 0.67, specificity = 0.93, PPV = 0.89 and NPV = 0.77).CONCLUSION Faecal calprotectin and MRI are two reliable tools to detect endoscopic POR in patients with CD. | Pierre Baillet Guillaume Cadiot Marion Goutte Felix Goutorbe Hedia Brixi Christine Hoeffel Christophe Allimant Maud Reymond Hélène Obritin-Guilhen Benoit Magnin Gilles Bommelaer Bruno Pereira Constance Hordonneau Anthony Buisson | 2018 | World Journal of Gastroenterology2018，24，5： | 1 |
| 5 | Multiscale reconstruction of tomographic images 显示文摘 | Zaim M Goutte R | 1992 | IEEE1992，，： | 1 |
| 6 | Diffusion - weighted imaging- nagative patients with transient ischernic attack are at risk of recurrent transient events显示文摘 | Boulanger JM Goutts SB Eliaziw M | 2007 | Stroke2007，38，8： | 1 |
| 7 | Combining NLP and probabilistic categorisation for document and term selection for Swiss-Prot medical armotation 显示文摘 | Dobrokhotov PB Goutte C Veuthey AL | 2003 | Bioinformatics2003，19，： | 1 |
| 8 | On clustering fMRI time series显示文摘 | Goutte C Toft P Rostrup E | 1998 | NeuroImage1998，9，： | 1 |
| 9 | Regularization with a pruning prior 显示文摘 | Hansen L K | 1997 | Neural Networks1997，10，6： | 1 |
| 10 | APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos显示文摘 | Goutte C Tsunozaki M Hale VA | 2002 | Proc Natl Acad Sci USA2002，99，2： | 1 |
| 11 | Structure properties of even-even actinides at normal and super deformed shapes analysed using the Gogny force显示文摘 | Delaroche J P Girod M Goutte H | 2006 | Nucl Phys2006，771，2： | 1 |
| 12 | APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos 显示文摘 | Goutte C Tsunozaki M Hale V A | 2002 | Proc Natl Acad Sci USA2002，99，2： | 1 |
| 13 | Tomographic con- struction of a 2D wavelet transform: continuous and dis- crete case显示文摘 | PEYRIN F ZAIM M GOUTTE R | 2008 | IEEE Transaction on Imformation Theory2008，42，6： | 1 |
| 14 | The importance of ambient sound level to characterise auran habitat 显示文摘 | Goutte S Dubois A Legendre F | 2013 | PLOS ONE2013，8，78： | 1 |
| 15 | A co-classification approach to learning from multilingual corpora显示文摘 | Amini M R Goutte C | | 0，，1： | 1 |
| 16 | Proton Pump Inhibitor Therapy Improves Symptoms in Postnasal Drainage显示文摘 | Michael F. Vaezi David D. Hagaman James C. Slaughter S. Bobo Tanner James A. Duncavage Christine T. Allocco Christy Sparkman Lynn E. Clement Cynthia M. Wasden Dana Wirth Marion Goutte Barbara A. McCafferty Donald C. Lanza | 2010 | Gastroenterology2010，，6： | 1 |
| 17 | Tomographic construction of a 2D Wavelet Transform: Continuous and Discrete Case 显示文摘 | Peyrin F Zaim M Goutte R | 2008 | IEEE Transaction on imformation theory2008，，： | 1 |
| 18 | APH-1 is a multipass membrane protein essential for the Notch signaling path- way in Caenorhabditis elegans embryos 显示文摘 | Goutte C Tsunozaki M Hale V A | 2002 | Proc Natl Aead Sci USA2002，99，2： | 1 |
| 19 | Word-sequence kernels显示文摘 | N Cancedda E Gaussier C Goutte | 2003 | Journal of Machine Learning Research2003，3，： | 1 |
| 20 | Image resolution enhancement using subpixel camera displacement 显示文摘 | Jacquemod G Odet C Goutte R | 1992 | Signal Processing1992，26，1： | 1 |
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