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| 1 | Synthetic aperture-based on-chip microscopy显示文摘Wide field-of-view(FOV)and high-resolution imaging requires microscopy modalities to have large space-bandwidth products.Lensfree on-chip microscopy decouples resolution from FOV and can achieve a space-bandwidth product greater than one billion under unit magnification using state-of-the-art opto-electronic sensor chips and pixel super-resolution techniques.However,using vertical illumination,the effective numerical aperture(NA)that can be achieved with an on-chip microscope is limited by a poor signal-to-noise ratio(SNR)at high spatial frequencies and imaging artifacts that arise as a result of the relatively narrow acceptance angles of the sensor’s pixels.Here,we report,for the first time,a synthetic aperture-based on-chip microscope in which the illumination angle is scanned across the surface of a dome to increase the effective NA of the reconstructed lensfree image to 1.4,achieving e.g.,,250-nm resolution at 700-nm wavelength under unit magnification.This synthetic aperture approach not only represents the largest NA achieved to date using an on-chip microscope but also enables color imaging of connected tissue samples,such as pathology slides,by achieving robust phase recovery without the need for multi-height scanning or any prior information about the sample.To validate the effectiveness of this synthetic aperture-based,partially coherent,holographic on-chip microscope,we have successfully imaged color-stained cancer tissue slides as well as unstained Papanicolaou smears across a very large FOV of 20.5 mm^(2).This compact on-chip microscope based on a synthetic aperture approach could be useful for various applications in medicine,physical sciences and engineering that demand high-resolution wide-field imaging. | Wei Luo Alon Greenbaum Yibo Zhang Aydogan Ozcan | 2015 | Light(Science & Applications)2015,4,1: | 4 |
| 2 | How low does ethical leadership flow? Test of a trickle-down model显示文摘 | David M. Mayer Maribeth Kuenzi Rebecca Greenbaum Mary Bardes Rommel (Bombie) Salvador | 2008 | Organizational Behavior and Human Decision Processes2008,,1: | 2 |
| 3 | The origin of the recent swine influenza A (HIN1) viru sinfecting humans显示文摘 | Trifonov V Khiabanian H Greenbaum B | 2009 | Eur Surveill2009,14,19: | 1 |
| 4 | Rituximab, B-Iymphocyte depletion, and preservation of beta -cell function显示文摘 | Pescovitz MD Greenbaum CJ Krause-SteinraufH | 2009 | N Engl J Med2009,361,22: | 1 |
| 5 | Monovision pseudophakia 显示文摘 | Greenbaum S | 2002 | J Cataract Refract Surg2002,28,: | 1 |
| 6 | Enhanced deposition of predominantly typeI collagen in myocardial disease显示文摘 | Bishop J E Greenbaum R Gibsonj D G | 1990 | J Mel Cell Cardiol1990,22,10: | 1 |
| 7 | Transfusion associated graft-versus-host disease:historical perspectives,incidence,and current use ofirradiated blood products显示文摘 | Greenbaum | 1991 | J Clinic Oncol1991,9,: | 1 |
| 8 | Mitochondrial localization and photodamage during photodynamic therapy with tetraphenylporphines 显示文摘 | WEIZMAN E ROTHMANN C GREENBAUM L | 2000 | J Photochem and Photobio B: Biology2000,59,1: | 1 |
| 9 | CCAAT enhancer-binding protein b is required for normal hepatocyte proliferation in mice after partial hepatectomy显示文摘 | Greenbaum LE Li W Cressman DE | 1998 | J Clin Invest1998,102,: | 1 |
| 10 | Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice显示文摘 | Cressman DE Greenbaum LE De Angelis RA | 1996 | Science1996,274,5291: | 1 |
| 11 | Change in mother-infant interactive behavior:relations to change in the mother,the infant,and the social context显示文摘 | Feildman R Greenbaum CW Mayas LC | 1997 | Infant Behavior and Development1997,20,2: | 1 |
| 12 | Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system显示文摘 | Greenbaum S Zhuang Y | 2002 | Proc Natl Acad Sci USA2002,99,15: | 1 |
| 13 | Preliminary experience with intravenous P2 Y12 platelet receptor inhibiti on as an adjunct to reduced-dose alteplase during acute myocardial infarction: results of the Safety, Tolerability and Effect on Patency in Acute Myocardial Infarction (STEP-AMI) angiographic trial 显示文摘 | Greenbaum AB Ohman EM Gibson CM | 2007 | Am Heart J2007,154,4: | 1 |
| 14 | Hospitalizations for severe lower respiratory tract infections显示文摘 | Greenbaum A H Chen J Reed C | 2014 | Pediatrics2014,134,3: | 1 |
| 15 | Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies 显示文摘 | Licht C Greenbaum LA Muus P | 2015 | Kidney International2015,87,5: | 1 |
| 16 | Monovision pseudophakia显示文摘 | Scott Greenbaum | 2002 | Journal of Cataract & Refractive Surgery2002,,8: | 1 |
| 17 | Impaired beta-cell function,incretin effect,and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose显示文摘 | Greenbaum CJ Prigeon RL D’AIessio DA | 2002 | Diabeles2002,51,4: | 1 |
| 18 | Unlocking the hidden value of concepts: A cognitive approach to business model innovation显示文摘 | Martins L L Rindova V P Greenbaum B E | 2015 | Strategic Entrepreneurship Journal2015,9,: | 1 |
| 19 | Concurrent poststreptococcal glomerutonephritis and autoimmune hemolytic anemia显示文摘 | Greenbaum LA Kerlin BA van Why S | 2003 | Pediatr Nephrol2003,18,12: | 1 |
| 20 | Characterization of nonthermal focused ultrasound for non-invasive selective fat celldisruption (lysis): technical and preclinical assessment 显示文摘 | Brown SA Greenbaum L Shtukmaster S | 2009 | Plast Reconstr Surg2009,24,1: | 1 |