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| 1 | Vitamin D deficiency is a risk factor for obesity and diabetes type 2 in women at late reproductive age显示文摘 | GRINEVA E N KARONOVA T MICHEEVA E | 2013 | Aging(Albany NY)2013，5，7： | 1 |
| 2 | The effect of metformin on the myocardial tolerance to ischemia-reperfusion injury in the rat model of diabetes mellitus type II显示文摘 | Kravchuk E Grineva E Bairamov A | 2011 | Exp Diabetes Res2011，2011，90： | 1 |
| 3 | Vitamin D defi- ciency is a risk factor for obesity and diabetes type 2 in women at late reproductive age 显示文摘 | Grineva EN Karonova T Micheeva E | 2013 | Aging (Albany NY)2013，5，7： | 1 |
| 4 | Effects of glucagon-like peptide 1 analogs in combination with insulin on myocardial infarct size in rats with type 2 diabetes mellitus显示文摘AIM To evaluate the effects of glucagon-like peptide-1 analogs(GLP-1 a) combined with insulin on myocardial ischemiareperfusion injury in diabetic rats.METHODS Type 2 diabetes mellitus(T2 DM) was induced in maleWistar rats with streptozotocin(65 mg/kg) and verified using an oral glucose tolerance test. After anesthesia, the left coronary artery was occluded for 40 min followed by 80 min reperfusion. Blood glucose level was measured during surgery. Rats were randomized into six groups as follows:(1) control rats;(2) insulin(0.1 U/kg) treated rats prior to ischemia;(3) insulin(0.1 U/kg) treated rats at reperfusion;(4) GLP-1 a(140 mg/kg) treated rats prior to ischemia;(5) GLP-1 a(140 mg/kg) treated rats at reperfusion; and(6) rats treated with GLP-1 a(140 mg/kg) prior to ischemia plus insulin(0.1 U/kg) at reperfusion. Myocardial area at risk and infarct size was measured planimetrically using Evans blue and triphenyltetrazolium chloride staining, respectively.RESULTS There was no significant difference in the myocardial area at risk among groups. Insulin treatment before ischemia resulted in a significant increase in infarct size(34.7% ± 3.4% vs 18.6% ± 3.1% in the control rats, P < 0.05). Post-ischemic administration of insulin or GLP-1 a had no effect on infarct size. However, pre-ischemic administration of GLP-1 a reduced infarct size to 12% ± 2.2%(P < 0.05). The maximal infarct size reduction was observed in the group treated with GLP-1 a prior to ischemia and insulin at reperfusion(8% ± 1.6%, P < 0.05 vs the control and GLP-1 a alone treated groups).CONCLUSION GLP-1 a pre-administration results in myocardial infarct size reduction in rats with T2 DM. These effects are maximal in rats treated with GLP-1 a pre-ischemia plus insulin at reperfusion. | Vladislav A Zykov Taisiia P Tuchina Denis A Lebedev Irina B Krylova Alina Y Babenko Elvira V Kuleshova Elena N Grineva Alekber A Bayramov Michael M Galagudza | 2018 | World Journal of Diabetes2018，9，9： | 1 |
| 5 | Photosynthesis, Respiration, and Transpiration in Maize Seedlings under Hypoxia Induced by Complete Flooding显示文摘 | T. V. Bragina I. S. Drozdova Yu. V. Ponomareva V. I. Alekhin G. M. Grineva | 2002 | Doklady Biological Sciences (-)2002，，1： | 1 |
| 6 | Improving nutrition for the prevention of gestational diabetes:Current status and perspectives显示文摘Gestational diabetes mellitus(GDM)is a common complication of pregnancy and a serious public health problem.It carries significant risks of short-term and longterm adverse health effects for both mothers and their children.Risk factors,especially modifiable risk factors,must be considered to prevent GDM and its consequences.Observational studies have identified several nutritional and lifestyle factors associated with the risk of GDM.The results of intervention studies examining the effects of diet and lifestyle on the prevention of GDM are contradictory.Differences in the study populations,types and intensity of intervention,time frame of the intervention,and diagnostic criteria for GDM may explain the heterogeneity in the results of intervention studies.This review provides an overview of new diets and other factors that may help prevent GDM.The main results of epidemiological studies assessing the risk factors for GDM,as well as the results and methodological problems of intervention studies on the prevention of GDM and their meta-analyses,are discussed.In addition,the evidence that gene and lifestyle interactions influence the development of GDM,as well as prospects for increasing the effectiveness of interventions designed to prevent GDM,including new data on the possible uses of personalized diet therapy,are highlighted. | Polina V Popova Evgenii A Pustozerov Aleksandra S Tkachuk Elena N Grineva | 2021 | World Journal of Diabetes2021，12，9： | 0 |
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