维普中文期刊产品整合服务
50篇 您的检索式:作者名="Grkovic"
    题名 作者 年代 出处 被引量
1New insights into BS69 functions显示文摘Velasco G Grkovic S Ansieau S 2006J Biol Chem2006,281,16:1
2Regulation of bacterial drug export systems 显示文摘Grkovic S Brown MH Skurray RA 2002Micro Mole Bio Rev2002,66,4:1
3Effect of peripheral axotomy on pain-related behavior and dorsal root ganglion neurons excitability in NPY transgenic rats显示文摘Sapunar D Modric-Jednacak K Grkovic I 0,,01:1
4Interactons of the QacR muhidrug-binding protein with structurally diverse ligands : implication for the evolution of the binding pocket 显示文摘Grkovic S Hardie KM Brown MH 2003Biochemistry2003,42,15:1
5Transcriptional regulation of multidrug efflux pumps in bacteria显示文摘Grkovic S Brown MH Skurray RA 2001Semin Cell DevBiol2001,12,3:1
6Structural mechanisms of QacR induction and multidrug recognition 显示文摘Schumacher MA Miller MC Grkovic S 2001Science2001,294,:1
7Transcriptional regulation of multidrug efflux pumps in bacteria显示文摘Grkovic S Brown MH Skurray RA 2001Semin Cell Dev Biol2001,12,3:1
8A systems approach using OSMAC,Log P and NMR fingerprinting:An approach to novelty显示文摘The growing number of sequenced microbial genomes has revealed a remarkably large number of secondary metabolite biosynthetic clusters for which the compounds are still unknown.The aim of the present work was to apply a strategy to detect newly induced natural products by cultivating microorganisms in different fermentation conditions.The metabolomic analysis of 4160 fractions generated from 13 actinomycetes under 32 different culture conditions was carried out by 1H NMR spectroscopy and multivariate analysis.The principal component analysis(PCA)of the 1H NMR spectra showed a clear discrimination between those samples within PC1 and PC2.The fractions with induced metabolites that are only produced under specific growth conditions was identified by PCA analysis.This method allows an efficient differentiation within a large dataset with only one fractionation step.This work demonstrates the potential of NMR spectroscopy in combination with metabolomic data analysis for the screening of large sets of fractions.Miaomiao Liu Tanja Grkovic Xueting Liu Jianying Han Lixin Zhang Ronald J.Quinn 2017Synthetic and Systems Biotechnology2017,2,4:1
9QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QaeA 显示文摘Grkovic S Brown M H Roberts N J 1998J Biol Chem1998,273,18:1
10The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers 显示文摘Grkovic S Brown M H Schumacher M A 2001J Bacteriol2001,183,24:1
11Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR 显示文摘Schumacher M A Miller M C Grkovic S 2002EMBO J2002,21,5:1
12IGFBP-3 bindsGRP78, stimulates autophagy and promotes the sur-vival of breast cancer cells exposed to adverse micro-environments 显示文摘Grkovic S’O’Reilly VC Han S 2013Oncogene2013,32,19:1
13Structural mechanisms of QacR induction and multidrug recognition 显示文摘Sehumaeher M A Miller M C Grkovic S 2001Science2001,294,:1
14QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA显示文摘Grkovic S Brown M H Roberts N J 1998J Biol Chem1998,273,18:1
15Interactions of the QacR multidrug-binding protein with structurally diverse ligands:implications for the evolution of the binding pocket显示文摘Grkovic S Hardie K M Brown M H 2003Biochemistry2003,42,15:1
16QacRis arepressor pro-teinthat regulates expression of the Staphy-lococcus aureus multidrugefflux pump QacA显示文摘Grkovic S Brown MH Roberts NJ 1998/ Biol Cftem1998,273,18:1
17Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR显示文摘Schumacher M A Miller M C Grkovic S 2002EMBO J2002,21,9:1
18Interactions of the QacR muhidrug-binding protein with structurally diverse ligands: implications for the evolution of the binding pocket显示文摘Grkovic S Hardie KM Brown MH 2003Biochemistry2003,42,15:1
19Transcriptional regulation of multidrug efflux pumps in bacteria显示文摘Grkovic S Brown MH Skurray RA 2001Semin Cell Dev Biol2001,12,:1
20Structural mech- anisms of QacR induction and multidrug recognition 显示文摘Schumacher MA Miller MC Grkovic S 2001Sci- ence2001,294,5549:1
返回顶部 每页显示:
共3页 首页 上一页 第1页 下一页 末页 /3 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费