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193篇 您的检索式:作者名="Groner"
    题名 作者 年代 出处 被引量
1一种进行基因表达研究的有效技术——小鼠全胚胎RNA原位杂交显示文摘目的 建立小鼠整体胚胎水平研究基因表达的方法。 方法 采用地高辛配基标记的造血相关基因 Runx1和神经发生相关基因 Runx3RNA探针 ,对 10 .5~ 14天小鼠全胚胎进行 RNA原位杂交 ,通过检测胚胎组织中 m RNA的存在状况来观察基因的表达。结果 在小鼠胚胎观察到 Runx1和 Runx3基因在不同组织中的清晰的杂交信号 ;不同探针和不同大小的胚胎需要不同的最适蛋白酶 K处理条件。 结论 小鼠全胚胎 RNA原位杂交技术是一种有效的研究基因表达的方法 ,可以从整体水平反映基因表达的全貌 ,在功能基因组学时代将具有很大的应用潜力 ,为基因表达研究提供了一种可与 L ac Z染色和免疫组织化学媲美的选择。蛋白酶 K处理条件是否适当是小鼠全胚胎 RNA原位杂交成功的关键因素。肖翠英 Ditsa Levanon 张思仲 Yoram Groner 2004中华医学遗传学杂志2004,21,1:3
2The function of Stat3 in tumor cells and their microenvironment显示文摘Bernd Groner Peter Lucks Corina Borghouts 2008Seminars in Cell and Developmental Biology2008,,4:2
3Analysis of human plasma products:polymerase chain reaction does not discriminate between live and inactivated vinmes显示文摘Hilfenhaus J Groner A Nowak T 1997Transfusion1997,37,9:1
4Mammalian target of rapamycin regulates the growth of mammary epithelial cells through the inhibitor of deoxyribonucleic acid binding Id1 and their functional differentiation through Id2 显示文摘Jankiewicz M Groner B Desrivieres S 2006Mol Endocrinol2006,20,10:1
5Multiple forms of prolactin receptor messenger ribonucleic acid are specifically expressed and regulated in murine tissues and the mammary cell line HC1 l显示文摘BUCK K VANEK M GRONER B et ol 1992Endocrinology1992,130,3:1
6Orthogonal polarization spectral imaging:a new method for study of the microcirculation显示文摘Groner W Winkelman JW Harris AG 1999Nat Med1999,5,:1
7Backward masking of words and faces: evidence for different processing speeds in the hemispheres? 显示文摘Heider B Groner R 1997Neuropsychologia1997,35,8:1
8Targeting survivin in cancer:novel drug development approaches显示文摘Groner B Weiss A 2014BioDrugs2014,28,1:1
9The function of Star3 in tumor cells and their microenvironment 显示文摘Groner B Lucks P Borghouts C 2008Semin Cell Dev Biol2008,19,4:1
10Induction of 3beta -hydrex- ystereid dehydregenase/deha5 -delta4 isomerase type 1 gene tran- serlption in human breast cancer cell lines and in normal mammary epithelial cells by interleukin -4 and interleukln - 13 显示文摘Gingras S Mor/ggl R Groner B et 8 1 1999Mol En- docrinol1999,13,1:1
11Overexpression and forced ac- tivation of stats in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlac- rational apoptosis显示文摘Iavnilovitch E Groner B Barash I 2002Mol Cancer Res2002,1,:1
12Prevalence and clinical predictors of Pneumocystis colonization among HIV- infected men显示文摘Morris A Kingsley LA Groner G 2004AIDS2004,18,5:1
13EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb- independent显示文摘Xu g Wu ZJ Groner AC 2012Science2012,338,14:1
14Linking landscape and species:effect of shrubs on patch preference of beetles in arid and semi-arid ecosystems显示文摘Shelef O Groner E 2011Journal of Arid Environments2011,75,10:1
15The IGF-1 receptor and its contributions to metastatic tumor growth-novel approaches to the inhibition of IGF-1R function显示文摘Bahr C Groner B 2005Growth Factors2005,23,1:1
16Lsoflurane and cerebmspinal fluid pressure in neurosurgical patients显示文摘ADAMS R W CUCCHIARA R F GRONER G A 1981Anesthesiology1981,54,2:1
17A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5-dependent luciferase gene expression显示文摘Storz P Dppler H Groner B 1999Anal Biochem1999,276,1:1
18The insulin like growth factor-! receptor (IGF-1 R) as a drug target: novel approaches to cancer therapy 显示文摘Bihr C Groner B 2004Growth Horm IGF Res2004,14,4:1
19Transcription factor regulation in mammary epithelial cells显示文摘Groner B 2002Domes Anim Endocrinol2002,23,12:1
20Comparison of the level,distribution and form of disease-associated prionprotein in variant and sporadiccreutzfeldt-jakob diseased brain usingconformation-dependent immunoassay and western blot显示文摘Choi YP Groner A Ironside JW 2011J Gen Virol2011,92,3:1
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