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| 1 | Cirrhotic cardiomyopathy:Isn't stress evaluation alwaysrequired for the diagnosis?显示文摘AIM:To describe the proportion of patients with cirrhotic cardiomyopathy(CCM) evaluated by stress echocardiography and investigating its association with the severity of liver disease.METHODS:A cross-sectional study was conducted.Cirrhotic patients without risk factors for cardiovascular disease were included.Data regarding etiology and severity of liver disease(Child-Pugh score and model for end-stage liver disease),presence of ascites and gastroesophageal varices,pro-brain natriuretic peptide(proBNP) and corrected QT(QTc) interval were collected.Dobutamine stress echocardiography(conventional and tissue Doppler imaging) was performed.CCM was considered present when diastolic and/or systolic dysfunction was diagnosed at rest or after pharmacological stress.Therapy interfering with cardiovascular system was suspended 24 h before the examination.RESULTS:Twenty-six patients were analyzed,17(65.4%) Child-Pugh A,mean model for end-stage liver disease(MELD) score of 8.7.The global proportion of patients with CCM was 61.5%.At rest,only 2(7.7%)patients had diastolic dysfunction and none of the patients had systolic dysfunction.Dobutamine stress echocardiography revealed the presence of diastolic dysfunction in more 6(23.1%) patients and of systolic dysfunction in 10(38.5%) patients.QTc interval prolongation was observed in 68.8%of the patients and increased pro-BNP levels in 31.2%of them.There was no association between the presence of CCM and liver impairment assessed by Child-Pugh score or MELD(P= 0.775,P= 0.532,respectively).Patients with QTc interval prolongation had a significant higher rate of gastroesophageal varices comparing with those without QTc interval prolongation(95.0%vs 50.0%,P= 0.028).CONCLUSION:CCM is a frequent complication of cirrhosis that is independent of liver impairment.Stress evaluation should always be performed,otherwise it will remain an underdiagnosed condition. | mara barbosa joana guardado carla marinho bruno rosa isabel quelhas antónio lourenco josécotter | 2016 | World Journal of Hepatology2016，8，3： | 5 |
| 2 | A computer model for calculating steep-fronted surge distribution in machine windings显示文摘 | Guardado J L Cornick K J | 1989 | IEEE Transactions on Energy Conversion1989，4，1： | 1 |
| 3 | Neoadjuvant radio- therapy and hormonotherapy in locally advanced breast cancer: state of the art显示文摘 | Padilha M Henriques M Guardado MJ | 2012 | Acta Med Port2012，25，6： | 1 |
| 4 | Multidrug-resis- tant acinetobacter meningitis in neurosurgical patients with intraventricular catheters:Assessment of different treatments 显示文摘 | Guardado AR Blanco A Asensi V | 2008 | Antimicrob Chemother2008，61，4： | 1 |
| 5 | Potential use of exenatide for the treat- ment of obesity 显示文摘 | Folli F Guardado Mendoza R | 2011 | Expert Opin Investig Drugs2011，20，12： | 1 |
| 6 | Multidrug-resistant Acinetobacter meningitis in neurosurgical patients with intraventricular catheters:assessment of different treatments显示文摘 | Rodríguez Guardado A Blanco A Asensi V | | 0，，04： | 1 |
| 7 | ESL students' experience of online peer feedback显示文摘 | Guardado M Shi L | 2007 | Computer and Composition2007，24，： | 1 |
| 8 | The inflammatory status score including IL - 6, TNF - α, osteopon- tin, fractalkine, MCP- 1 and adiponectin underlies whole- body insulin resistance and hyperglycemia in type 2 diabetes meflitus显示文摘 | DANIELE G GUARDADO MENDOZA R WINNIER D | 2014 | Acta Diabetol2014，51，1： | 1 |
| 9 | Mul- tidrug-resistant Acinetobacter meningitis in neurosurgical patients with intraventricular catheters : assessment of dif- ferent treatments显示文摘 | Rodriguez Guardado A Blanco A Asensi V | 2008 | J Antimicrob Chemother2008，61，4： | 1 |
| 10 | Some structural and electronic features of the interaction of phosphate with metal-humic complexes显示文摘 | Guardado I Urrutia O Garcia-Mina J M | 2008 | Journal of Agricultural and Food Chemistry2008，56，3： | 1 |
| 11 | A comparative study of neural network efficiency in power transformers diagnosis using dissolved gas analysis 显示文摘 | Guardado J L Naredo J L Moreno P | 2001 | IEEE Transactions on Power Delivery2001，16，4： | 1 |
| 12 | A comparative study of neural network efficiency in power transformers diagnosis using dissolved gas analysis显示文摘 | Guardado J L Naredo J L Moreno P | 2001 | IEEE Transactions on Power delivery2001，16，10： | 1 |
| 13 | A comparative study of neural network efficiency in power transformers diagnosis using dissolved gas analysis 显示文摘 | Guardado J L Naredo J L Moreno P | 2001 | IEEE Transactions on Power delivery2001，16，10： | 1 |
| 14 | Muhidrug-resistant Acinetobacter meningitis in neurosurgical patients withintraventricular catheters: assessment of difierenttreatments显示文摘 | Rodriguez Guardado A Blanco A Asensi V | 2008 | JAntimicrobChemother2008，61，4： | 1 |
| 15 | The inflammatory status score including IL-6,TNF-α,osteopontin,fractalkine,MCP-1 and adiponectin underlies whole-body insulin resistance and hyperglycemia in type 2 diabetes mellitus显示文摘 | DANIELE G GUARDADO MENDOZA R WINNIER D | 2014 | Acta Diabetol2014，51，1： | 1 |
| 16 | An im- proved arc model before current zero based On the combined Mayr and Cassie arc models显示文摘 | GUARDADO J L MAXIMOV S G MELGOZA E | 2005 | IEEE Transactions on Power Delivery2005，20，1： | 1 |
| 17 | Neoadjuvant radio- therapy and hormonotherapy in locally advanced breast cancer: state of the art显示文摘 | Padilha M Henriques M Guardado M J | 2012 | Acta Med Port2012，25，6： | 1 |
| 18 | A computer model for calculating steep-fronted surge distribution in machine windings显示文摘 | Guardado J L Cornick K J | 1989 | IEEE Translation on Energy Conversion1989，4，1： | 1 |
| 19 | Mitral and aortic valve aneurysm secondary to infective endocarditis:impressive images of a rare echocardiographic finding显示文摘 | Azevedo O Ferreira F Guardado J | | 0，，： | 1 |
| 20 | Decline in rotavirus hospi- talizations and health care visits for childhood diarrhea following ro- tavirus vaccination in E1 salvador 显示文摘 | Yen C Guardado JA Alberto P | 2011 | Pediatric Infectious Disease Journal2011，30，： | 1 |
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