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| 1 | Pacemaker therapy in very elderly patients: survival and prognostic parameters of single center experience显示文摘Background Permanent pacing is the therapy of choice for treating severe and/or symptomatic bradyarrhythmias. The number of very elderly patients receiving pacemakers is increasing and little is known about survival in this specific subgroup. This study is aimed at assessing the actual survival of patients requiring pacing therapy at age > 85 years and investigating variables associated with death. Methods Between 2010 and 2017, 572 patients aged ≥ 85 years underwent pacemaker implantation for conventional bradycardia indications in Department of Cardiology, S. Chiara Hospital, Italy. Results Thirty percent of patients were ≥ 90-year-old and comorbidities were frequent. Fifty-seven percent of patients required pacing for prognostic reasons(acquired atrioventricular block), and the remaining for relief of bradycardia symptoms. A dual-chamber pacemaker was implanted in 34% of patients. The 5-year survival was 45%(standard error: 3%), and the 8-year survival was 26%(standard error: 4%). The risk of death was similar in patients who received pacemaker for symptom relief and for prognostic reasons in the overall population(HR = 1.19, 95% CI: 0.93–1.52, P = 0.156), as well as in the ≥ 90-year-old group(HR = 1.39, 95% CI: 0.92–2.11, P = 0.102). At multivariate analysis, following variables were associated with death: higher age, lower ejection fraction, dementia/dysautonomia and diagnosis of cancer. The pacing indication and the implantation of a single chamber pacemaker were not associated with worse prognosis. Conclusions This study showed a good life expectancy in patients aged ≥ 85 years who received a pacemaker. Strong risk factors for all-cause death were non-cardiac. Pacemaker therapy seems a clinically effective therapeutic option to improve survival and to control bradyarrhythmia-related symptoms in very elderly patients. | Massimiliano Marini Marta Martin Michela Saltori Silvia Quintarelli Filippo Zilio Fabrizio Guarracini Alessio Coser Sergio Valsecchi Roberto Bonmassari | 2019 | Journal of Geriatric Cardiology2019，16，12： | 3 |
| 2 | Which is the best catheter to perform atrial fibrillation ablation? A comparison between standard ThermoCool, SmartTouch, and Surround Flow catheters显示文摘 | Luigi Sciarra Paolo Golia Andrea Natalizia Ermenegildo Ruvo Serena Dottori Antonio Scarà Alessio Borrelli Lucia Luca Marco Rebecchi Alessandro Fagagnini Alberto Bandini Fabrizio Guarracini Marcello Galvani Leonardo Calò | 2014 | Journal of Interventional Cardiac Electrophysiology2014，，： | 1 |
| 3 | Function limiting dyses thetic pain syndrome among traumatic SCI patients: a cross sectional study显示文摘 | Davidoff G Roth E Guarracini M | 1987 | Pain1987，29，： | 1 |
| 4 | Function limiting dysesthetic pain syndrome among traumatic SCI patients: a cross sectional study显示文摘 | Davidoff G Roth E Guarracini M | 1987 | Pain1987，29，1： | 1 |
| 5 | Function-limiting dysesthetic pain syndrome among traumatic spinal cord inju- ry patients: a cross-sectional study显示文摘 | Davidoff G Roth E Guarracini M | 1987 | Pain1987，29，1： | 1 |
| 6 | Accuracy of N-terminal pro-brain natriuretic peptide in the identification of left ventricular dysfunction in high-risk asymptomatic patients 显示文摘 | Romano S Neeozione S Guarracini L | 2009 | J Cardiovasc Meal2009，10，3： | 1 |
| 7 | Accuracy of N- terminal pro-brain natriuretic peptide in the identification of left ventricular dysfunction in high-risk asymptomatic pa- tients显示文摘 | Romano S Necozione S Guarracini L | 2009 | J Cardiovase Med2009，10，3： | 1 |
| 8 | Function limiting dysesthetic pain syndrome among traumatic SCI patients:acrossectional study显示文摘 | Davidoff G Roth E Guarracini M | | 0，，： | 1 |
| 9 | Accuracy of N-terminal pro-brain natriuretic peptide in the identification of left ventricular dysfunction in high-risk asymptomatic patients显示文摘 | Romano S Necozione S Guarracini L etal | 2009 | J Cardiovasc Med2009，10，3： | 1 |
| 10 | Accuracy of N-terminal pro-brain natriuretic peptide in the identification of lett ventricular dysfunction in high-risk asymptomatic patients显示文摘 | Romano S Necozione S Guarracini L | 2009 | J Cardiovasc Med2009，10，3： | 1 |
| 11 | Accuracy of N-terminal pro-brain natriuretic peptide in the identification of left ventricular dysfunction in high-risk asymptomatic patients显示文摘 | Romano S Necozione S Guarracini L | 2009 | J Cardiovasc Med2009，10，3： | 1 |
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