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460篇 您的检索式:作者名="Gurkan"
    题名 作者 年代 出处 被引量
1Premature ejaculation: current and future treatments显示文摘早泄(PE ) 被认出是最普通的男性混乱。因为有食物药品管理局(食物及药品管理局) 同意的既不一个普遍接受的定义也不药, PE 为对待这个条件的专业人员提供困难。尽管有这些缺点,医生们继续根据主要指南与 PE 诊断他们的病人并且与行为的治疗或离开标签药对待他们。这评论为 PE 集中于当前、新兴的治疗选择和药。每种治疗选择的优点和限制根据当前的出版考察同伴的文学被讨论。Levent Gurkan Matthew Oommen Wayne J. G. Hellstrom 2008Asian Journal of Andrology2008,10,1:15
2Comparison of double balloon enteroscopy in adults and children显示文摘AIM: To compare results of double balloon enteroscopy (DBE) procedures in pediatric and adult patients. METHODS: The medical files of patients who underwent DBE at Gazi University School of Medicine, Ankara, Turkey between 2009 and 2011 were examined retrospectively. Adult and pediatric patients were compared according to DBE indications, procedure duration, final diagnosis, and complications. DBE procedures were performed in an operating room under general anesthesia by two endoscopists. An oral or anal approach was preferred according to estimated lesion sites. Overnight fasting of at least 6 h prior to the start of the procedure was adequate for preprocedural preparation of oral DBE procedures. Bowel cleansing was performed by oral administration of sennosides A and B solution, 2 mL/kg, and anal saline laxative en-ema. The patients were followed up for 2 h after the procedure in terms of possible complications. RESULTS: DBE was performed in 35 patients (5 pediatric and 30 adult). DBE procedures were performed for abdominal pain, chronic diarrhea, bleeding, chronic vomiting, anemia, and postoperative evaluation of anastomosis. Final diagnosis was diffuse gastric angiodysplasia (n = 1); diffuse jejunal angiodysplasia (n = 1); ulceration in the bulbus (n = 1); celiac disease (n = 1); low differentiated metastatic carcinoma (n = 1); PeutzJeghers syndrome (n = 1); adenomatous polyp (n = 1) and stricture formation in anastomosis line (n = 1). During postprocedural follow-up, abdominal pain and elevated amylase levels were noted in three patients and one patient developed abdominal perforation. CONCLUSION: With the help of technological improvements, we may use enteroscopy as a safe modality more frequently in younger and smaller children.Odul Egritas Gurkan Tarkan Karakan Ibrahim Dogan Buket Dalgic Selahattin Unal 2013World Journal of Gastroenterology2013,19,29:11
3Effect of early preoperative 5-fluorouracil on the integrity of colonic anastomoses in rats显示文摘AIM:To determine the effect of chemotherapy on wound healing by giving early preoperative 5-fluorouracil (5-FU)to rats with colonic anastomoses. METHODS:Sixty Albino-Wistar male rats(median weight,235 g)were used in this study.The rats were fed with standard laboratory food and given tap water ad libitum.The animals were divided into three groups: Group 1:Control group(chemotherapy was not administered),Group 2:Intraperitoneally(IP)administered 5-FU group(chemotherapy was administered IP to animals at a dose of 20 mg/kg daily during the 5 d preceeding surgery),Group 3:Intravenously(IV)administered 5-FU group.Chemotherapy was administered via the penil vein,using the same dosing scheme and duration as the second group.After a 3-d rest to minimize the side effects of chemotherapy,both groups underwent surgery.One centimeter of colon was resected 2 cm proximally from the peritoneal reflection,thensutured intermittently and subsequently end-to-end anastomosed.In each group,half the animals were given anaesthesia on the 3rd postoperative(PO)day and the other half on the 7th PO day,for in vivo analytic procedures.The abdominal incisions in the rats were dissected,all the new and old anastomotic segments were clearly seen and bursting pressures of each anastomotic segment,tissue hydroxyproline levels and DNA content were determined to assess the histologic tissue repair process. RESULTS:When the IV group was compared with the IP group,bursting pressures of the anastomotic segments on the 3rd and 7th PO days,were found to be significantly decreased,hydroxyproline levels at the anastomotic segment on the 7th PO day were significantly decreased(P<0.01). CONCLUSION:In this study,we conclude that early preoperative 5-FU,administered IV,negatively affects wound healing.However,IP administered 5-FU does not negatively affect wound healing.Leyla Ozel M Sefa Ozel Ahmet Burak Toros Melih Kara Kemal Sirri Ozkan Gurkan Tellioglu Osman Krand Meral Koyuturk Ibrahim Berber 2009World Journal of Gastroenterology2009,15,33:7
4Impact of admission blood glucose levels on prognosis of elderly patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention显示文摘OBJECTIVE:Admission hyperglycemia in acute myocardial infarction (MI) is related with increased in-hospital and long term mortality and major cardiac adverse events。 We aimed to investigate how admission hyperglycemia affects the short and long term outcomes in elderly patients >65 years) after primary percutaneous coronary intervention for ST elevation myocardial infarction。 METHODS:We retrospectively analyzed 677 consecutive elderly patients (mean age 72.2 ±5.4)。 Patients were divided into two groups according to admission blood glucose levels。 Group : low glucose group (LLG), glucose < 168 mg/dL; and Group 2: high glucose group (HGG), glucose >168 mg/dL。 RESULTS:In-hospital, long term mortality and in-hospital major adverse cardiac events were higher in the high admission blood glucose group (P <0.001)。 Multivariate regression analysis showed: Killip > 1, post-thrombolysis in MI <3 and admission blood glucose levels were independent predictors of in-hospital adverse cardiac events (P <0.001)。 CONCLUSIONS:Admission hyperglycemia in elderly patients presented with ST elevation myocardial infarction is an independent predictor of in-hospital major adverse cardiac events and is associated with in-hospital and long term mortality。Ahmet Ekmekci Mahmut Uluganyan Fatif Tufan Huseyin Uyarel Gurkan Karaca Seref Kul Barl(s) Gungor 2013Journal of Geriatric Cardiology2013,10,4:6
5Precancerous lesions of oral mucosa显示文摘Precancerous lesions of oral mucosa, known as potentially malignant disorders in recent years, are consists of a group of diseases, which should be diagnosed in the early stage. Oral leukoplakia, oral submucous fibrosis, and oral erythroplakia are the most common oral mucosal diseases that have a very high malignant transformation rate. Oral lichen planus is one of the potentially malignant disorders that may be seen in six different subtypes including papular, reticular, plaquelike, atrophic, erosive, and bullous type, clinically. Atrophic and erosive subtypes have the greater increased malignant transformation risk compared to another subtypes. Although there are various etiological studies, the etiology of almost all these diseases is not fully understood. Geographically, etiologic factors may vary.The most frequently reported possible factors are tobacco use, alcohol drinking, chewing of betel quid containing areca nut, and solar rays. Early diagnosis is very important and can be lifesaving, because in late stages, they may be progressed to severe dysplasia and even carcinoma in situ and/or squamous cell carcinoma. For most diseases, treatment results are not satisfactory in spite of miscellaneous therapies. While at the forefront of surgical intervention, topical and systemic treatment alternatives such as corticosteroids, calcineurin inhibitors, and retinoids are widely used.Gurkan Yardimci Zekayi Kutlubay Burhan Engin Yalcin Tuzun 2014World Journal of Clinical Cases2014,2,12:5
6Subfoveal choroidal thickness changes after intravitreal bevacizumab therapy for neovascular age-related macular degeneration显示文摘Dear Sir,Iam Dr.Cihanünlü,from the Department of Opthalmology,ümraniye Training and Research Hospital,Istanbul,Turkey.I write to present our study findings on subfoveal choroidal thickness(SFCT)changes after intravitreal bevacizumab(IVB)therapy for neovascular age-related macular degeneration(AMD).AMD is the leading cause of severe visual loss in adults older than 60y[1].Visual loss in late stages of AMD may be the result of one of the two processes:geographic atrophy(GA)or choroidal neovascularization(CNV).Many typesCihan ünlü Gurkan Erdogan Betul Onal Gunay Betul Ilkay Sezgin Akcay Esra Kardes 2015International Journal of Ophthalmology(English edition)2015,8,4:3
7Differential diagnosis in ulcerative colitis in an adolescent: Chronic granulomatous disease needs extra attention显示文摘Chronic granulomatous disease(CGD) is a primary immune deficiency that is commonly diagnosed under the age of 5 years(95%) and is rarely seen in adulthood. CGD may manifest as inflammatory bowel disease(IBD) in childhood. Without proper diagnosis, these patients may be monitored for years as IBD; some may even be regarded as steroid-resistant ulcerative colitis(UC) and end up having a colectomy. In this case report, we described a patient who had been followedup for years as UC and subsequently underwent colectomy, but was finally diagnosed in adulthood as primary immune deficiency.Daniel Kotlarz Odul Egritas Gurkan Zehra Sule Haskologlu Ozgur Ekinci Aysel Aksu Unlusoy Neslihan Gürcan Kaya Jacek Puchalka Cristoph Klein Buket Dalgic 2017World Journal of Gastrointestinal Pathophysiology2017,8,2:2
8Mini-incision total hip arthroplesty: a comparative assessment of perioperative outcomes 显示文摘Wenz James F Gurkan llksen Jibodh Stefan R 2002Orthopedics2002,25,10:2
9Distal humeral coronal plane fractures: management, complications and outcome显示文摘Mehmet Oguz Durakbasa Gurkan Gumussuyu Mutlu Gungor Mehmet Nurullah Ermis 2012Journal of Shoulder and Elbow Surgery2012,,:2
10Bone change after castration in rats: a model for osteoporosis显示文摘 Ekeland A Gantvik KM 1986Acta Orthop Scand1986,57,1:1
11Thrombotic thrombocytopenic purpura in southern Turkey:A single-center experience of 29 cases显示文摘Gurkan E Baslamisli F Guvenc B 2005Clin Lab Haematol2005,27,2:1
12Surgical treatment of malignant tumors of the sacrum显示文摘Ozdemir MH Gurkan I Yildiz Y 1999Eur Surg Oncol1999,25,1:1
13Mini-incision total hip arthroplasty:a comparative assessment of perioperative outcomes显示文摘Wenz JF Gurkan I Jibodh SR 2002Orthopedic2002,25,:1
14Marginal donors in kidney transplantation显示文摘Kacar S Gurkan A Varilsuha C 0,,04:1
15Mixed medullary- papillary carcinoma of the thyroid: Report of two cases and review of the literature 显示文摘Gurkan E Gurbuz Y Tarkun I 2014Indian J Pathol Microbi- ol2014,57,4:1
16Thrombotic thrombocytopenic purpura in southern Turkey:a single-center experience of 29cases显示文摘Gurkan E Baslamisli F Guvenc B 2005Clin Lab Haematol2005,27,2:1
17Intravenous dexmedetomidine, but not midazolam,prolongs bupivacaine spinal anesthesia 显示文摘Fatma NK Belgin Y Gurkan T 2010Can J Anaesth2010,27,1:1
18The mechanical environment of bone marrow:a review显示文摘Gurkan UA Akkus O 0,,:1
19A ease of autoimmune thy- roiditis and membranoproliferative glomerulonephritis 显示文摘Gurkan S Dikman S Saland JM 2009Pe- diatr Nephrol2009,24,1:1
20A randomized, open-label study of sirolimus versus cyelosporine in primary de novo renal allograft recipients 显示文摘Flechner SM Gurkan A Hartmann A 2013Transplantation2013,95,10:1
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