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| 1 | Hepatitis B virus mutations potentially conferring adefovir/ tenofovir resistance in treatment-naive patients显示文摘Anti-hepatitis B virus(HBV)therapy leads to the emer- gence of mutant viral strains during the treatment of chronic hepatitis B with nucleos(t)ides analogues. The existence of HBV variants with primary antiviral resistance may be important for treatment choice. We studied two patients with chronic HBV infection by sequencing the HBV polymerase gene.They had adefovir-and tenofovir-related mutations in the viral polymerase,although they had never been treated. These mutations were rtV214A/rtN238T in one patient and rtA194T in the other.Thus,mutations in untreated patients deserve cautious surveillance.These data indicate that mutations that can theoretically confer adefovir or tenofovir resistance may emerge in treatmentnaive patients. | Rebecca Pastor Franois Habersetzer Samira Fafi-Kremer Michel Doffoёl Thomas F Baumert Jean-Pierre Gut Franoise Stoll-Keller Evelyne Schvoerer | 2009 | World Journal of Gastroenterology2009，15，6： | 6 |
| 2 | Value of indirect hem agglutination and coagglutiation test for serotyping Haemophilus parasuis显示文摘 | Del Rio M L Gut ierrez B C Rodriguez Ferri E F | 2003 | Clin Microbio 12003，41，2： | 1 |
| 3 | Diversity in the response to low temperature in representative barley genotypes cultivated in Europe显示文摘 | RIZZA F PAGANI D GUT M | 2011 | Crop Science Society of America2011，51，： | 1 |
| 4 | Eveduationg of'set-up deviations during the irradiation of patients suffering from breast cancer treated with two different techniques显示文摘 | Kukolowiez P F Debrowski A Gut P | 2005 | Radiother Oncol2005，25，1： | 1 |
| 5 | A large-scale, consortium-based genomewide association study of asthma 显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N Engl J Med2010，863，： | 1 |
| 6 | A large-scale, consortium- based genome-wide association study of asthma 显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N Engl J Med2010，363，： | 1 |
| 7 | Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03) 显示文摘 | Le Clerc S Limou S Coulonges C Carpentier W Dina C Taing L Delaneau O Labib T Sladek R ANRS Genomic Group Deveau C Guillemain H Ratsimandresy R Montes M Spadoni JL Therwath A Schichter F Matsuda F Gut I Leli6vre JD L6vy Y Froguel P Delfraissy JF Hercberg S Zagury JF | 2009 | Infect Dis2009，200，8： | 1 |
| 8 | Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn' s disease显示文摘 | Baert F Moortgat L Van Assche G Belgian Inflammatory Bowel Disease Research Group North- Holland Gut Club | 2010 | Gastroenterology2010，138，2： | 1 |
| 9 | A larg-scale, consortium- based genomewide association study of asthma显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N Engl J Med2010，363，13： | 1 |
| 10 | Experimental and numerical heat transfer in a plate heat exchanger显示文摘 | GALEAZZO F C C MIURA R Y GUT J A W | 2006 | Chemical Engineering Science2006，，61： | 1 |
| 11 | When did the Emeishan man- tle plume activity start? Geochronological and geochemical evi- dence from ultramafic-mafic dikes in Southwestern China显示文摘 | Gut F Fan W M Wang Y J | 2004 | In- ternational Geology Review2004，46，3： | 1 |
| 12 | Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins显示文摘 | GUT A KAPPELER F HYKA N | 1998 | EMBO J1998，17，： | 1 |
| 13 | A large-scale, consortium- based genome-wide association study of asthma显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N Engl J Med2010，363，13： | 1 |
| 14 | Experimental and numerical heat transfer in a plate heat exchanger显示文摘 | GALEAZZO F C C MIURA R Y GUT J A W | 2006 | Chemical Engineering Science2006，61，21： | 1 |
| 15 | A large-scale,consortium-based genomewide association study of asthma显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N Engl J Med2010，363，13： | 1 |
| 16 | Effect of monitoring trap and mating disruption dispenser application heights on captures of male Graphplita molesta(Busck:Lepidoptera:Tortricidae)in pheromone and virgin female-baited traps显示文摘 | De Lame F M Gut L J | 2006 | Environmental Entomology2006，35，4： | 1 |
| 17 | A Large-Scale, Consor- tium-Based Genomewide Association Study of Asthma显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N En- gl J Med2010，363，13： | 1 |
| 18 | A large-scale, consortium- based genomewide association study of asthma 显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | New England J Med2010，363，13： | 1 |
| 19 | A large-scale, consortium-based genomewide association study of asthma显示文摘 | Moffatt MF Gut IG Demenais F | 2010 | N Eng J Med2010，36，3： | 1 |
| 20 | Future potential of the Human Epigenome Project显示文摘 | Eckhardt F Beck S Gut I G | 2004 | Expert Rev Mol Diagn2004，4，5： | 1 |
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