| 2 | Correlation between macular ganglion cell-inner plexiform layer thickness and visual acuity after resolution of the macular edema secondary to central retinal vein occlusion显示文摘AIM: To examine the thickness of the ganglion cell-inner plexiform layer(GCIPL) in eyes with resolved macular edema(ME) in non-ischemic central retinal vein occlusion(CRVO), applying spectral-domain optical coherence tomography(SD-OCT), and its relationship with visual acuity.METHODS: The retrospective observational case-control study included 30 eyes of non-ischemic CRVO patients with resolved ME(ME eyes) after treatment, and 30 eyes of non-ischemic CRVO patients without ME(non-ME eyes). The macular GCIPL thickness, peripapillary retinal nerve fiber layer(p RNFL) thickness and central macular thickness(CMT) were measured on a SD-OCT scan. Linear regression analyses were performed to determine the correlation between the thickness of each and the visual acuity(VA).RESULTS: No significant difference in average GCIPL thickness, mean pR NFL thickness and CMT were observed between ME group and non-ME group(P=0.296, 0.183, 0.846). But, minimum GCIPL thickness was reduced in ME eyes compared with non-ME eyes(P=0.022). Final VA significantly correlated with the minimum GCIPL thickness in ME eyes(r=-0.482, P=0.007), whereas no correlation was found with average GCIPL thickness, average pR NFL thickness and mean CMT.CONCLUSION: Minimum GCIPL thickness is reduced in ME eyes compared with non-ME eyes, and correlated with the VA in non-ischemic CRVO. These results propose that inner retinal damage occurring in patients with ME secondary to non-ischemic CRVO may lead to permanent visual defect after treatment. | Hyun Ju Kim Han Gyul Yoon Seong Taeck Kim | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 1 |
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