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71篇 您的检索式:作者名="H Genant"
    题名 作者 年代 出处 被引量
1健康老年妇女近段股骨骨密度和结构的定量CT研究显示文摘目的采用定量CT(QCT)和双能X线吸收测量(DXA)仪对健康老年妇女近段股骨骨密度(BMD)和骨结构进行研究,并对2种测量方法的结果进行比较。方法对66名65岁以上健康妇女左侧髋关节进行DXA测量,计算出股骨颈和粗隆区BMD;对其双侧近段股骨进行QCT测量,计算出股骨颈、粗隆区和整体股骨ROI的皮质骨、松质骨和总体骨的BMD和体积;并将QCT三维图像模拟DXA的平面投影计算出模拟DXA股骨颈BMD和模拟DXA股骨粗隆区BMD。对所获数据进行配对t检验或非参数秩和检验,并用Pearson法分析DXA和QCT相对应ROI的相关性。结果用QCT可以对股骨近段不同ROI(股骨颈、粗隆区和整体股骨区)及不同骨成分(皮质骨、松质骨和总体骨)的BMD及体积等参数进行精确的定量分析。除右侧股骨颈皮质骨BMD[(0.52±0.04)g/cm^3]、股骨粗隆区皮质骨BMD[(0.49±0.03)g/cm^3]、股骨粗隆区综合骨BMD[(0.22±0.04)g/cm^3]大于左侧相应参数[分别为[(0.51±0.04)、(0.48±0.03)、(0.21±0.04)g/cm^3],差异均有统计学意义(P值均〈0.05),但差别均〈3.3%;而模拟DXA股骨颈BMD、模拟DXA股骨粗隆区BMD、股骨颈皮质骨体积、股骨颈松质骨BMD、股骨颈松质骨体积、股骨颈综合骨BMD、股骨颈综合骨体积、股骨粗隆区皮质骨体积、股骨粗隆区松质骨BMD、股骨粗隆区松质骨体积、股骨粗隆区综合骨体积左侧参数分别为(0.52±0.10)g/cm^2、(0.78±0.13)g/cm^2、5.80cm^3、(0.06±0.03)g/cm^3、(5.19±1.40)cm^3、(0.25±0.04)g/cm^3、15.66cm^3、(21.74±3.43)cm^3、(0.08±0.03)g/cm^3、(34.27±6.09)cm^3、(76.12±11.11)cm^3,右侧分别为(0.52±0.10)g/cm^2、(0.78±0.13)g/cm^2、6.01cm^3、(0.06±0.02)g/cm^3、(5.17±1.27)cm^3、(0.25±0.04)g/cm^3、15.62cm^3、(22.12±3.60)cm^3、(0.09±0.03)g/cm^3、(34.17±5.94)cm^3、(76.53±10.71)cm^3,差异均无统计学意义(P值均〉0.05)。左右两侧近段股骨QcT各相对应参数之间的r值范围在0.656~0.955,均具有相关性(P〈0.05)。QcT模拟DXA股骨颈和粗隆区BMD与真正DXA测量的相应值之间r值分别为0.685和0.855,具有相关性(P〈0.05)。结论利用QCT技术可以对老年妇女近段股骨不同区域和不同成分的BMD和结构进行精确定量分析,QCT是骨质疏松研究中非常有用的测量技术。程晓光 Li Jing 刘霞 王予生 李谨 屈辉 H Genant T Lang 2009中华放射学杂志2009,43,2:8
2Clinical applications of body composition measurements using DXA显示文摘ALBANESE C V DIESSEL E GENANT H K 2003Journal of Clinical Densitometry2003,6,2:1
3Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures:a prospective, controlled, randomized study of four hundred and fifty patients显示文摘GOVENDER S CSIMMA C GENANT H K 2002J Bone Joint Surg Am2002,84,12:1
4Effects of abatacept in patients with methotrexate,resistant active rheumatoid arthritis:a randomized trial显示文摘Kremer J M Genant H K Moreland L W 2006Ann Intern Med2006,144,:1
5Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis显示文摘Genant H Jergas M Palermo L 1996J Bone Miner Res1996,11,:1
6Quantitative bone mineral analysis using dual energy computed tomography显示文摘Genant H Cann C 1977Invest Radiol1977,12,6:1
7Vertebral fracture assessmentusing a semiquantitative technique显示文摘Genant H K Wu C Y Kuijc C 1993Bone Miner Res1993,8,9:1
8Recombinant human bone morphogenetic protein -2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients显示文摘Govender S Csimma C Genant H K 20021 BoneJoint Surg Am2002,84,12:1
9Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures : a prospective, controlled, randomized study of four hundred and fifty patients 显示文摘Covender S Csimma C Genant H K 2002J Bone Joint Surg(Am)2002,84,12:1
10Clinical applications of body composition measurements using DXA显示文摘ALBANESE C V DIESSEL E GENANT H K 2003J Clin Densitom2003,6,2:1
11Quantitative compu ted tomography of vertebral spongiosa: a sensitive method for de tecting early bone loss after oophorectomy显示文摘Genant H K Cann C E Ettinger B 1982Ann Intern Med1982,97,5:1
12Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis显示文摘Hill CL Hunter DJ Niu J Clancy M Guermazi A Genant H 2007Ann Rheum Dis2007,66,:1
13Lumbar spinal fusion : Assessment of functional stability with magnetic resonance imaging 显示文摘Lang P Chafetz n Genant H K 1990Spine1990,15,:1
14Advanced CT bone imaging in osteoporosis显示文摘Genant H K Engelke K Prevrhal S 2008Rheumatology (Oxford)2008,47,4:1
15Low-dose esterified estrogen therapy:effects on bone,plasma estrodiol concentrations,endometrium,and lipid levels显示文摘Genant H K Lucas J Weiss S 1997Arch Intern Med1997,157,22:1
16Effects of Risedronate on Vertebral and on Vertebral Fractures in Women with Postmenopausal Osteoporosis:a Randomized Controlled Trial显示文摘Harris S T Watts N B Genant H K 0,,:1
17Severity of vertebral fracture reflects deterioration of bone microarchitecture显示文摘GENANT H K DELMAS P D CHEN P 2007Osteoporos Int2007,18,1:1
18Noninvasive assessment of bone mineral and structure:state of the art显示文摘Genant H K Engelke K Fuerst T 1996J Bone Miner Res1996,11,6:1
19Outcome assessment in clinical trials of fracture-healing显示文摘Morshed S Corrales L Genant H 2008J Bone Joint Surg(Am)2008,90,1:1
20Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures:a p rospective,controlled,randomized study of four hundred and fifty patients显示文摘Govender S Cristina C Genant H K 2002J Bone Joint Surg Am2002,84,12:1
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