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| 1 | Hypofractionated stereotactic rad iotherapy alone without whole-brain irradiation for patien ts with solitary and oligo brain metastasis using noninvasive fixation of the skull显示文摘To evaluate the efficacy and toxicity of hypofractionated stereotactic radiotherapy(HSRT)using noninvasive fixation of the sk ull on solitary or oligo brain metastatic p atients as an alternative to stereotactic radiosurgery(SRS)using invasive fixation.The subjects were 87patients who had 4or fewer brain meta stases(50solitary,37oligometastases).Treatment was conducted on 159meta stases by using a linac-based stereotactic system.T he median isocentric dose was 35Gy in4fractions.Whole-brain irradiati on was not applied as an initial treatment.For the salvage treatmen t of metachronous brain metastases,repeat HSRT or whole-brain irradiation was applied.The actuarial1-year local tumor control rate was 81%.Treatment-related complicatio ns were observed in 4patients in the e arly period(<3months)and in 2patients in the late period.T he median survival period was 8.7mon ths.Metachronous brain metastases occurred in 30patients,and none of the 18patients who were eligible for salvage HSRT refused to re ceive it again.Hypofractionated stereotactic radiotherapy achieved tumor control and survival equivalent to those of SRS reported i n the literature.The results suggested that HSRT could be an alternative for solitary or oligo br ain metastatic patients with less to xicity and less invasiveness compared to | Aoyama H Shirato H Onimaru R Kagei K Ikeda J Ishii N Sawamura Y Miyasaka K | 2003 | 癌症2003，22，7： | 12 |
| 2 | Hypofractionated stereotacticradiotherapy ( HypoFXSRT) for stage I non-small cell lung cancer;updated results of 257 patients in a Japanese multi -institutionalstudy显示文摘 | Onishi H Shirato H Nagata Y | 2007 | J Thorac Oncol2007，2，13： | 1 |
| 3 | Stereotactic radiosurgery pluswhole - brain radiation therapy vs stereotactic radiosurgery alonefor treatment of brain metastases : a randomized controlled trial显示文摘 | Aoyama H Shirato H Tago M | 2006 | J Am Med Assoc2006，295，： | 1 |
| 4 | Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy显示文摘 | Seppenwoolde Y Shirato H Kitamura K | 2002 | Int J Radiat Oncol Biol Phys2002，53，4： | 1 |
| 5 | Genetic and antigenic diversity among noroviruses 显示文摘 | Hansman GS Natori K Shirato - Horikoshi H | 2006 | J Gen Virol2006，87，4： | 1 |
| 6 | Impact of respiratory movement on the computed tomographic images of small lung tumors in three-dimensional (3D) radiotherapy显示文摘 | SHIMIZU S SHIRATO H KAGEI K | 2000 | Int J Radiat Oncol Biol Phys2000，46，5： | 1 |
| 7 | Field Observation of the Full-Scale Wind-Induced Cable Vibration显示文摘 | MATSUMOTO M SHIRATO H YAGI T | 2003 | Journal of Wind Engineering and Industrial Aerodynamics2003，91，1： | 1 |
| 8 | Stereotatic hypofrac-donated high dose irradiation for stage I non - small cell lungcancer:clinical outcomes in 245 subjects in a Japanese mul-tiinstitutional study显示文摘 | Onishi M Araki T Shirato H | 2004 | Cancer2004，10，1： | 1 |
| 9 | Norovirus and histo-blood group antigens显示文摘 | Shirato H | 2011 | Jpn J Infect Dis2011，64，2： | 1 |
| 10 | Precise and real -time measurement of 3D tumour motion in lung due to breathing and heart beat, measured during radiotherapy 显示文摘 | Seppenwoolde Y Shirato H Kitamura K | 2002 | Int J Radiat Oncol Biol Phys2002，53，45： | 1 |
| 11 | Impact of re- spiratory movement in the computed tomographic images of small lung tumors in three- dimensional ( 3D ) radiotherapy 显示文摘 | SHIMIZU S S SHIRATO H KAGEI K | 2000 | Int J Radiat Oncol Biol Phys2000，46，5： | 1 |
| 12 | Precise and real time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy 显示文摘 | SEPPENWOOLDE Y SHIRATO H KITAMURA K | 2002 | Int J Radiat Oncol Biol Phys2002，53，4： | 1 |
| 13 | Tolerance of organs at risk in small volume, hypofractionated, image - guided radiother- apy for primary and metastatic lung cancers显示文摘 | Onimaru R Shirato H Shimizu S | 2003 | Int J Radiat On- col Biol Phys2003，56，： | 1 |
| 14 | Tolerance of organs at risk in small-volume,hypofractionated,image-guided radiotherapy for primary and metastatic lung cancers显示文摘 | Onimaru R Shirato H Shimizu S | 2003 | Int J Radiat Oncol Biol Phys2003，56，1： | 1 |
| 15 | Stereotactic body radio-therap for operable stage I non - small cell lung cancer: CanSBRT be comparable to surgery 显示文摘 | Onishi H Shirato H Nagata Y | 2010 | Int J Rad Oncol2010，78，2： | 1 |
| 16 | Effects of aerodynamic interferences between heaving and torsional vibration of bridge decks: the case of Tacoma Narrows Bridge显示文摘 | Matsumoto M Shirato H Yagi T | 2003 | Journal of Wind Engineering and Industrial Aerodynamics2003，91，： | 1 |
| 17 | Germ cell tumours of the central nervoussystem: treatment consideration based on 111 cases and their long-term clinical outcomes 显示文摘 | SAWAMURA Y IKEDA J SHIRATO H | 1998 | Eur J Cancer1998，34，： | 1 |
| 18 | High speed magnetic resonance imaging for four-dimensional treatment planning of conformal radiotherapy of moving body tumours显示文摘 | Shimizu S Shirato H Aoyama H | 2000 | Int J Radiat Oncol Biol Phys2000，48，2： | 1 |
| 19 | Changes in topographical features and soil properties after enclosure combined with sand-fixing measures in Horqin Sandy Land, northern China 显示文摘 | SHIRATO Y ZHANG T H OHKURO T | 2006 | Soil Science and Plant Nutrition2006，51，1： | 1 |
| 20 | Spanwise coherence characteristics of surface pressure field on 2-D bluff bodies显示文摘 | MATSUMOTO M SHIRATO H ARAKI K | | 0，，12： | 1 |
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