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| 1 | Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats显示文摘Background : Osteoporosis can make bone repair difficult. Low-level laser therapy( LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology. Methods : Fifty-four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups(n = ?6 per group), and 24 hours after the bone defects were created they received three, six or 12 sessions of LLLT at 0, 20 or 30 J/cm 2, using a 780-nm low-intensity GaAlAs laser. One-way ANOVA followed by Tukey ' s post hoc test was used for data processing. A difference of P < 0.05 was considered statistically significant. The parameters evaluated were osteocyte density( Nv_(ost)), total osteocyte number( Nto ost), trabecular surface density( Sv_t), and trabecular surface area( Sa_t). Results : Data obtained showed that Nto ost, Sv t, and Sa t in group G2 rats were significantly different from G1(0 J/cm^2)( P < 0.05). Compared to group G4, G5 presented higher values for the parameters Sv t and Sa t, and G6 presented significantly higher values for almost all the analyzed parameters( Nv _(ost), Nto_(ost), Sv_t, and Sa t)( P < 0.05). Compared to group G7, G8 showed a higher value only for the parameter Sa t, and G9 showed significantly higher values for parameters Nv ost, Nto ost, Sv_t, and Sa_t. Conclusion : We conclude that LLLT stimulated bone neoformation and contributed to an increase in the total number of osteocytes, especially with a laser energy density of 30 J/cm^2 given for six and 12 sessions. | Priscilla Hakime Scalize Luiz Gustavo de Sousa Lígia Maria Napolitano Goncalves Dimitrius Leonardo Pitol Marcelo Palinkas Antonio Augusto Coppi Mariah Acioli Righeti Vitória Ricardo Karina Fittipaldi Bombonato-Prado Simone Cecílio Hallak Regalo Selma Siessere | 2019 | Animal Models and Experimental Medicine2019，2，1： | 2 |
| 2 | Aggregation behavior of nanoparticles in fluidized beds 显示文摘 | HAKIM L PORTMAN J CSAPER M WEIMER A | 2005 | Powder Technol2005，160，3： | 1 |
| 3 | Lymphocyte toxicity and T cell receptorexcision circles in workers exposed to benzene 显示文摘 | Lan Q Zhang L Hakim F | 2005 | Chem Biol Interact2005，，： | 1 |
| 4 | The ability of helical CT to preoperatively stage endometrial carcinoma显示文摘 | Hardesty L A Sumkin J H Hakim C | 2001 | AJR2001，176，3： | 1 |
| 5 | Synthesis of novel chitosan resin derivatized with serine diacetic acid moiety and its application to on-line collection/concentration of trace elements and their determination using inductively coupled plasma-atomic emission spectrometry显示文摘 | Hakim L Sabarudin A Oshima M | 2007 | Analytica Chimica Acta2007，588，： | 1 |
| 6 | A graph theoretic approach to conceptual design with functional perspectives 显示文摘 | HAKIM L A KUSIAK A MATHEW J | 2000 | Computer Aided Design2000，32，14： | 1 |
| 7 | Structural studies of three sesquiterpenes from Litsea spp (Lauraceae) 显示文摘 | Hakim E H Achmad S A Effend E L | 1993 | AustJChem1993，46，9： | 1 |
| 8 | Synthesis of crosslinked chitosan functionalized with threonine moiety and its application to on-line collection/concentration and determination of Mo,V and Cu显示文摘 | Hakim L Sabarudin A Oshita K | 2008 | Talanta2008，74，： | 1 |
| 9 | The association of hyperglycemia with cerebral edema in atroke显示文摘 | Berger L Hakim AM | 1986 | Stroke1986，17，5： | 1 |
| 10 | Surgical technique to maintain penile length after insertion of an inflatable penile prosthesis via infrapubic approach显示文摘 | Borges F Hakim L Kline C | 2006 | J Sex Med2006，3，3： | 1 |
| 11 | Long - termresults of muhimodal therapy for chroni cprostatitis/chronic pelvic pain syndrome 显示文摘 | Shoskes DA Hakim L Ghoniem G Jackson CL | 2003 | J Urol2003，169，： | 1 |
| 12 | True view blade improves laryngeal view when compared to Macintosh blade显示文摘 | Lieberman N Hakim A R Lemberg L Berkenstadt H | 2003 | Anesthesiology2003，99，： | 1 |
| 13 | Synth ized with on-line tion of (1) ; 9 SIS SABARUDIN A, OSHITA K, et of cross-linked chitosan functional- threonine moiety collection/concentration its application to and determina- Mo, V and Cu显示文摘 | HAKIM L al | 2008 | Talanta2008，7，： | 1 |
| 14 | Factors affecting membrane fouling reduction by surface modification and backpulsing显示文摘 | Ma H Hakim L F Bowman C N | 2001 | J Membr Sci2001，189，： | 1 |
| 15 | Use of FWD data for prediction of bonding between pave- ment layers 显示文摘 | Hakim B A Cheung L W Armitage R J | 1999 | International Journal of Pavement Engineering1999，1，1： | 1 |
| 16 | graph-theoretic approach to conceptual design with functional perspectives显示文摘 | HAKIM L A | 2000 | Computer-Aided Design2000，32，： | 1 |
| 17 | Factors affecting membrane fouling reduction by surface modification and backpulsing显示文摘 | Ma H Hakim F L Bowman C N | 2001 | Journal of Membrane Science2001，189，2： | 1 |
| 18 | Scorpion toxin, bmp01, induces pain by targeting trpvl channel 显示文摘 | Hakim M A Jiang W Luo L | 2015 | Toxins ( Ba- sel)2015，7，： | 1 |
| 19 | Leukocyte antigenrelated deficiency enhances insulin-like growth factor-1 signaling in vascular smooth muscle cells and promotes neointima formation in response to vascular injury显示文摘 | Niu X L Li J Hakim Z S | 2007 | J Biol Chem2007，282，19： | 1 |
| 20 | FAK regulates cardiomyocyte survival following ischemia/reperfusion 显示文摘 | HAKIM Z S DIMICHELE L A ROJAS M | 2009 | Journal of Molecular and Cellular Cardiology2009，46，： | 1 |
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