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125篇 您的检索式：作者名="HASS G"

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	题名	作者	年代	出处	被引量
1	Identification of osteopontin as the most consistently over-expressed gene in intrahepatic cholangiocarcinoma: Detection by oligonucleotide microarray and real-time PCR analysis显示文摘AIM: To investigate the molecular pathways involved in human cholangiocarcinogenesis by gene expression profiling. METHODS: Oligonucleotide arrays (Affymetrix U133A) were used to establish a specific gene expression profile of intrahepatic CCC in comparison to corresponding non- malignant liver tissue. To validate the expression values of the most overexpressed genes, RT-PCR experiments were performed. RESULTS: Five hundred and fifty-two statistically differentially expressed genes/ESTs (221 probes significantly up-regulated, 331 probes down-regulated; P < 0.05; fold change > 2; ≥ 70%) were identified. Using these data and two-dimensional cluster analysis,a specific gene expression profile was obtained allowing fast and reproducible differentiation of CCC, which was confirmed by supervised neuronal network modelling. The most consistently overexpressed gene (median fold change 33.5, significantly overexpressed in 100%) encoded osteopontin. Furthermore, an association of various genes with the histopathological grading could be demonstrated. CONCLUSION: A highly specific gene expression profile for intrahepatic CCC was identified, allowing for its fast and reproducible discrimination against non- malignant liver tissue and other liver masses. The most overexpressed gene in intrahepatic CCC was the gene encoding osteopontin. These data may lead to a better understanding of human cholangiocarcinogenesis.	Holger G Hass Oliver Nehls Juergen Jobst Andrea Frilling Ulrich Vogel Stephan Kaiser	2008	World Journal of Gastroenterology2008，14，16：	4
2	A characterization of polymethylmethacrylate bone cement显示文摘	Hass SS Brauer GM Dickson G	1975	J Bone Joint Surg1975，57，4：	3
3	Downhole emulsification:viscosity reduction increases production显示文摘	Browne G E Hass G R Sell R D	1996	JCPT1996，35，4：	1
4	Chapter 19:The role of collagen in peripheral nerve repair显示文摘	Koopmans G Hasse B Sinis N		0，，：	1
5	Identification and characteri-zation of the virus causing rabbit hemorrhagic disease显示文摘	Ohlinger V F Hass B Meyers G	1990	J Viral1990，64，7：	1
6	Zur Wirkung van natnrlichem Eisenoxid in Form-und Kernformstoffffen auf die Obefflaeehenqualitaet von Gussstuecken显示文摘	G Pokomy	1995	Giesserei-Rundshau Teil 11995，42，34：	1
7	Reflectance and optical constants of evaporated osmium in the vacuum ultraviolet from 300 to 2000 A显示文摘	COX J T HASS G RAMSEY J B	1973	J Opt Soc Am1973，63，：	1
8	Calcitionin gene-related peptide and peripheral nerve regeneration显示文摘	Dumoulin F L Raivich G Hass C A	1992	Ann NY A cad Sci1992，，657：	1
9	Optical properties of evaporated iridium in the vacuum ultraviolet from 500 Angstroms to 2000 Angstroms显示文摘	HASS G JACOBUS G F HUNTER W R	1967	JOSA1967，57，6：	1
10	Identification of prostate specific membrane antigen (PSMA) as the target of monoclonal antibody 107-1A4 by proteinchip: array surface-enhanced laser desorption/ionization (SELDI) technology显示文摘	WANG S DIAMOND D L HASS G M	2001	Cancer2001，92，6：	1
11	The use of simultaneous chemical precipitation in modified activated sludge systems exhibiting biological excess phosphate removal Part 4 :experimental periods using ferric chloride显示文摘	de Hass D W Wentzel M C Ekama G A	2000	Water SA2000，26，4：	1
12	Land resource impact indicators of urban sprawl显示文摘	Hasse J E Lathrop R G	2003	Applied Geography2003，23，2：	1
13	Identification and charac- teri-zation of the virus causing rabbit hemorrhagic disease显示文摘	Ohlinger VF Hass B Meyers G	1990	J Viral1990，64，7：	1
14	The comfort automatic tuning project显示文摘	Weikum G Hasse C Monkeberg A	1994	Information Systems1994，19，5：	1
15	The use of simultaneous chemical precipitation in modified activated sludge systems exhibiting biological excess phosphate removal Part 5 : experimental periods using a ferrous-ferric chloride blend 显示文摘	de Hass D W Wentzel M C Ekama G A	2001	Water SA2001，27，2：	1
16	A highly reusable rhodium catalyst-organic framework for the intramolecular cycloisomerization of 1,6-enynes显示文摘	CORKUM E G HASS M J SULLIVAN A D		0，，13：	1
17	Increased hemorrhagic risk after repeated infusion of highly substituted medium molecular weight hydroxyethl starch显示文摘	Trib J Hass A Pindur G	1997	Arzneim Forsch/Drug Res1997，46，：	1
18	The use of simultaneous chemical precipitation in modified activated sludge systems exhibiting biological excess phosphate removal Part 6 :modelling of simultaneous chemical-biogical P removal-review of existing models 显示文摘	de Hass D W Wentzel M C Ekama G A	2000	Water SA2000，26，4：	1
19	Downhole emulsification : viscosity reduction increases production 显示文摘	Browne G E Hass G R Sell R D	1996	Journal of Canadian Petroleum Technology1996，35，4：	1
20	Land Resource Impact Indicators of Urban Sprawl显示文摘	Hasse J E Lathrop R G	2003	Applied Geography2003，23，：	1

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