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| 1 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 2 | Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum:A case series and systematic literature review显示文摘BACKGROUND Heterotopic pancreas(HP)is an aberrant anatomic malformation that occurs most commonly in the upper gastrointestinal tract.While the majority of heterotopic pancreatic lesions are asymptomatic,many manifest severe clinical symptoms which require surgical or endoscopic intervention.Understanding of the clinical manifestations and symptoms of HP is limited due to the lack of large volume studies in the literature.The purpose of this study is to review symptomatic cases at a single center and compare these to a systematic review of the literature in order to characterize common clinical manifestations and treatment of this disease.AIM To classify the common clinical manifestations of heterotopic pancreas.METHODS A retrospective review was conducted of pathologic samples containing heterotopic pancreas from 2000-2018.Review was limited to HP of the upper gastrointestinal tract due to the frequency of presentation in this location.Symptomatic patients were identified from review of the medical records and clinical symptoms were tabulated.These were compared to a systematic review of the literature utilizing Pub Med and Embase searches for papers pertaining to heterotopic pancreas.Publications describing symptomatic presentation of HP were selected for review.Information including demographics,symptoms,presentation and treatment were compiled and analyzed.RESULTS Twenty-nine patient were identified with HP at a single center,with six of these identified has having clinical symptoms.Clinical manifestations included,gastrointestinal bleeding,gastric ulceration with/without perforation,pancreatitis,and gastric outlet obstruction.Systemic review of the literature yielded 232 publications detailing symptomatic cases with only 20 studies describing ten or more patients.Single and multi-patient studies were combined to form a cohort of 934 symptomatic patients.The majority of patients presented with abdominal pain(67%)combined with one of the following clinical categories:(1)Dyspepsia,(n=445,48%);(2)Pancreatitis(n=260,28%);(3)Gastrointestinal bleeding(n=80,9%);and(4)Gastric outlet obstruction(n=80,9%).The majority of cases(n=832,90%)underwent surgical or endoscopic resection with 85%reporting resolution or improvement in their symptoms.CONCLUSION Heterotopic pancreas can cause significant clinical symptoms in the upper gastrointestinal tract.Better understanding and classification of this disease may result in more accurate identification and treatment of this malformation. | Michael T Le Compte Brandon Mason Keenan J Robbins Motoyo Yano Deyali Chatterjee Ryan C Fields Steven M Strasberg William G Hawkins | 2022 | World Journal of Gastroenterology2022，28，14： | 3 |
| 3 | Standardized measurement of the future liver remnant prior to extended liver resection: Methodology and clinical associations显示文摘 | Jean-Nicolas Vauthey Amin Chaoui Kim-Anh Do Malcolm M Bilimoria Marc J Fenstermacher Chuslip Charnsangavej Marshall Hicks Guido Alsfasser Gregory Lauwers Irvin F Hawkins James Caridi | 2000 | Surgery2000，，5： | 2 |
| 4 | Rock compressibility and failure as reservoirs in geopressured gas reservoirs 显示文摘 | Harville D W Hawkins M F | 1969 | JPT December1969，1528，： | 2 |
| 5 | Transcriptomic changes in human breast cancer progression as determined by serial analysis of gene expression显示文摘 | DRAKE J A HAWKINS K A | 2004 | Breast Cancer Res2004，6，5： | 1 |
| 6 | Rickettsia and mollicute infections in hapatopancreatic cells of cultured Pacific white shrimp (Penaeus vannamei)显示文摘 | Krol R M Hawkins W E Overstreet R M | 1991 | J Invertebr Pathol1991，59，： | 1 |
| 7 | Matrix metalloproteinase inhibitors显示文摘 | Wojtowicz-Praga S Dickson R B Hawkins M J | 1997 | Invest New Drugs1997，15，1： | 1 |
| 8 | Mariana Trough basalts (MTB):Trace element and Sr-Nd isotopic evidence for mixing between MORB-like and arc-like melts显示文摘 | VOLPE A M MACDOUGALL J D HAWKINS J W | 1987 | Earth and Planetary Science Letters1987，82，： | 1 |
| 9 | Performance of Precast/Prestressed Concrete Building Structures during Northridge Earthquake 显示文摘 | lverson James k Neil M Hawkins | 1994 | PCI Jouranal1994，，2： | 1 |
| 10 | Shear transfer in rein- forced concrete-recent research 显示文摘 | Mattock A H Hawkins N M | 1972 | 17 (2) : 55 -751972，17，2： | 1 |
| 11 | The efficacy and toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex (ARC):an open uncontrolled treatment study显示文摘 | Stambuk D Youle M Hawkins D | | 0，，262： | 1 |
| 12 | Plasma uric acid remains a marker of poor outcome in hypertensive pregnancy: a retrospective cohort study 显示文摘 | HAWKINS T L ROBERTS J M MANGOS G J | 2012 | B JOG- An International Journal of Obstetrics and Gynaecology2012，119，4： | 1 |
| 13 | The tapered MILO显示文摘 | Eastwood J W Hawkins K C Hook M P | 1998 | IEEE Trans Plasma Sci1998，26，3： | 1 |
| 14 | Robust estimation of the variogram显示文摘 | CRESSIE N HAWKINS D M | 1980 | Mathematical Geology1980，12，2： | 1 |
| 15 | Constructing a validity argument for the mini-Clinical Evaluation Exercise: a review of the research显示文摘 | Hawkins R E Margolis M J Durning S J | 2010 | Academic Medicine2010，85，9： | 1 |
| 16 | Load Transfer Mechanisms in Pile and Pile Groups 显示文摘 | O' NELL M W HAWKINS R S MAHAR L J | 1982 | Geotechnical Engineering ASCE1982，108，12： | 1 |
| 17 | The Changepoint Model for Statistical Process Control 显示文摘 | Hawkins D M Peihua Q Chang W K | 2003 | Journal of Quality Technology2003，35，4： | 1 |
| 18 | Extinction risk in the sea显示文摘 | ROBERTS C M HAWKINS J P | 1999 | Trends in Ecology and Evolution1999，14，： | 1 |
| 19 | Runoff curve number:has it reached maturity显示文摘 | PONCE V M HAWKINS R H | 1996 | Hydrologic Engineering1996，1，1： | 1 |
| 20 | Execution of super oxide - induced cell death by the proapoptotic Bcl - 2 - related proteins Bid and Bak 显示文摘 | Madesh M Zong W X Hawkins B J | 2009 | Mol Cell Biol2009，29，11： | 1 |
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