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23篇 您的检索式:作者名="HEDIN N"
    题名 作者 年代 出处 被引量
1Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing显示文摘The impact of the microenvironment on innate lymphoid cell(ILC)-mediated immunity in humans remains largely unknown.Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcriptional profiles and heterogeneity of CD127+ILCs across four human tissues.Correlation analysis identified gene modules characterizing the migratory properties of tonsil and blood ILCs,and signatures of tissue-residency,activation and modified metabolism in colon and lung ILCs.Trajectory analysis revealed potential differentiation pathways from circulating and tissue-resident naïve ILCs to a spectrum of mature ILC subsets.In the lung we identified both CRTH2+and CRTH2−ILC2 with lung-specific signatures,which could be recapitulated by alarmin-exposure of circulating ILC2.Finally,we describe unique TCR-V(D)J-rearrangement patterns of blood ILC1-like cells,revealing a subset of potentially immature ILCs with TCR-δ rearrangement.Our study provides a useful resource for in-depth understanding of ILC-mediated immunity in humans,with implications for disease.Luca Mazzurana Paulo Czarnewski Viktor Jonsson Leif Wigge Markus Ringnér Teresa CWilliams Avinash Ravindran Åsa KBjörklund Jesper Säfholm Gunnar Nilsson Sven-Erik Dahlén Ann-Charlotte Orre Mamdoh Al-Ameri Charlotte Höög Charlotte Hedin Sylwester Szczegielniak Sven Almer Jenny Mjösberg 2021Cell Research2021,31,5:2
2Lead extraction:Indications and techniques显示文摘Byrd CL Schwartz SJ Hedin N 1992J Cardiol Clin1992,10,:1
3Advanced series compensation with thyristor controlled impedance 显示文摘CHRISTL N HEDIN R SADEK K 1992CIGRE Paper1992,11,7:1
4Carbon dioxide captureon amine-rich carbonaceous materials derived from glu-cose显示文摘Zhao L Bacsik Z Hedin N 2010Chem Sus Chem2010,3,7:1
5Nonsurfactant supramoleeular synthesis of ordered mesoporous silica 显示文摘Atluri R Hedin N Garcia-Bennett A E 2009J Am Chem Soc2009,131,9:1
6Zeolites and related sorbents with narrow pores for CO2 separation from flue gas 显示文摘Cheung O Hedin N 2014RSC Advances2014,4,14:1
7Nitrogen and phosphorus interact to control tropical symbiotic N2 fixation : a test in Inga punctata显示文摘Batterman S A Wurzburger N Hedin L O 2013Journal of Ecology2013,101,6:1
8Nanostructural features of demosponge biosilica显示文摘Weaver JC Pietrasanta LI Hedin N 2003J Struct Biol2003,144,:1
9lead extraction: indications and techniques显示文摘Byrd CL Schwartz SJ Hedin N 1992J Cardiol Clin1992,10,:1
10Lead extraction:Indication and techniques显示文摘Byrd CL Schwartz SJ Hedin N 1992Cardiology Clinics1992,10,:1
11显示文摘HEDIN N FURO I ERIKSON P O 2000J Phys Chem2000,104,:1
12显示文摘HEDIN N SITNIKOV R FURO I 1999J Phys Chem1999,103,:1
13Temporal trends in nitrogen isotope values of nitrate leaching from an agricultural soil显示文摘Ostrom N E Knoke K E Hedin L O 1998Chem Geol1998,146,34:1
14Lead extraction:indication and techniques显示文摘Byrd CL Schwartz SJ Hedin N 1992Cardiol Clin1992,10,4:1
15Comparison of anti-CD20 and anti-CD45 antibodies for conventional and pretargeted radioimmunotherapy of B-cell lymphomas显示文摘Pagel JM Hedin N Subbiah K 2003Blood2003,101,6:1
16Lead extaction:Indication and techniques显示文摘Byrd CL Schwartz SJ Hedin N 1992Cardiol Clin1992,10,4:1
17Lead extraction:indication and techniques显示文摘Byrd CL Schwartz SJ Hedin N 1992Cardiol Clin1992,10,4:1
18Eradication of disseminatedleukemia in a syngeneic murine leukemia model using pretai^eted anti-CD45 radioimmunotherapy 显示文摘Pagel JM Hedin N Drouet L 2008Blood2008,111,4:1
19Mechanisms and kinetics for sorption of CO2 on bicontinuous mesoporous silica modified with n-propylamine显示文摘Bacsik Z Ahlsten N Ziadi A Zhao G Garcia-Bennett A E Martin-Matute B Hedin N 0,,17:1
20Interactions of charged porphyrins with nonionic triblock copolymer hosts in aqueous solutions显示文摘Steinbeck C A Hedin N Chmelka B F 2004Langmuir2004,20,10:1
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