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216篇 您的检索式:作者名="HENG H"
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1A unique sequence in the N-terminal regulatory region controls the nuclear localization of KLF8 by cooperating with the C-terminal zinc-fingers显示文摘Kr 眉 p 像像素的因素 8 (KLF8 ) 抄写因素在房间周期前进起一个关键作用, oncogenic 转变,对间充质的转变和侵略上皮。然而,它的原子本地化信号(NLS ) 没被识别。有另外的 KLF monopartite NLS (mNLS ) 和 C2H2 锌手指(ZF ) 的 KLF8 份额,哪个被显示了是为一些另外的 KLF 的 NLS。在这份报告,用指导 PCR 的 mutagenesis 和 immunofluorescent 显微镜学,我们显示出 mNLSs,任何单个 ZF 的删除,或变化的那混乱 Zn2+ 有约束力或联系 DNA 主题没影响 KLF8 的原子本地化。删除 > 然而,从 C 终点的 1.5 ZF 引起了 KLF8 的细胞质的累积。令人惊讶地,氨基酸(aa ) 的删除 151-200 区域几乎从原子核消除了 KLF8。有 PKC 禁止者的 S165A, K171E 或 K171R 变化,或处理导致了部分细胞质的累积。Co-immunoprecipitation 证明 KLF8 与 importin- 交往了,这个相互作用要求了 ZF 主题。aa 1-150 或 201-261 区域的删除独自没改变原子本地化。BrdU 加入和 cyclin D1 倡导者酶试金作为野类型的 KLF8 证明在原子本地化的 KLF8 异种有缺陷者不能支持 DNA 合成或 cyclin D1 倡导者激活。一起拿,这些结果建议 KLF8 有二 NLS,一包围 S165 和 K171 并且另外的是二双人脚踏车 ZF,它为 KLF8 原子本地化和它的细胞的功能的规定是批评的。Tina S Mehta Heng Lu Xianhui Wang Alison M Urvalek Kim-Hang H Nguyen Farah Monzur Jojo D Hammond Jameson Q Ma Jihe Zhao 2009Cell Research2009,19,9:10
2Mini-Cog测试结果与老年骨折患者并发症及谵妄高风险有关显示文摘既位对于围手术期危险因素的分析,通常采用美国麻醉医师协会(American Society of Anesthesiologists,ASA)评分等全身状态分类方法。Mini-Cog测试是一种快速、易行、有效且观察者间变异较小的认知评估工具,可测量急性应激状态下患者在执行功能障碍和回忆方面的认知储备。Heng M Eagen CE Javedan H 胡玮 杨进城 2016中国骨科临床与基础研究杂志2016,8,4:3
3Analysis of marker or complex chromosomal rearrangements present in pre-and post-natal karyotypes utilizing a combination of G-banding,spectral karyotyping and fluorescence in situ hybridization 显示文摘Heng H H Ye C J Yang F 2003Clin Genet2003,63,5:1
4Cross sectional echocardiography, 3: analysis of mathematic models for quantifying volume of symmetric and asymmetric left ventricles显示文摘WYATT H L MEERBAUM S HENG M K 1980Am Heart J1980,100,:1
5Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis显示文摘Motoyama J Heng H Crackower MA 0,,:1
6Keyword guessing attacks on secure searchable public key encryption schemes with a designated tester显示文摘Yan W C Phan R C Heng S H 2013International Journal of Computer Mathematics2013,90,12:1
7The immunogenicity and immunomoduclatory fucnction of osteogenic cells differentiated from mesenchymal stem cells显示文摘Liu H Kemeny DM Heng BC 2006J Immuol2006,176,5:1
8Late complication after singie-rod instrumentation显示文摘Hengeness M H Esses S I Wellborn C C 2010Spine2010,24,1:1
9High resolution free ehromatin/DNA fiber fluorescent in situ hybridization显示文摘Heng H H Tsui L C 1998J Chromatogr A1998,806,1:1
10Direct nanoimprinting of metal nanoparticles for nanoscale electronics fabrication显示文摘SEUNG H K 1NKYU P HENG P 2007Nano Letters2007,7,7:1
11Pressure effects on natural convection for non-Boussinesq fluid in a rectangular enclosure显示文摘 C heng C H 2002Numerical Heat Transfer2002,41,3:1
12The use of prognostic factors inmetastatic renal cell carcinoma 显示文摘Li H Samawi H Heng DY 2015Urol Oncol2015,33,:1
13Critical success factors of inter-organizational information systems-a case study of cisco and xiao tong in china 显示文摘Lu X-H Huang L-H Heng M S H 2006Informarion & Management2006,43,:1
14Non-linear response of a mixed land use watershed to nitrogen loading 显示文摘Nikolaidis N P Heng H Semagin R 1998Agriculture Ecosystem and Environment1998,67,3:1
15Charging for network security based on long-run incremental cost pricing显示文摘HENG H Y LI F WANG X 2009IEEE Trans Power Syst2009,24,4:1
16Therapeutic angiogenesis by transplantation of human embryonic stem cellderived CD133+ endothelial progenitor cells for cardiac repair显示文摘RUFAIHAH A J HAIDER H K HENG B C 2010Regen Med2010,5,2:1
17The murine Xe169 gene escapes X-inactivation like its human homologue显示文摘 Salido E C Yen P H Mohandas T K Heng H H Tsui L C Park J Chapman V M Shapiro L J 1994Nat Genet1994,7,:1
18Effects of castration on thymocyte development in two different models of thymic involution显示文摘Heng T S Goldberg G L Gray D H 2005Immunology2005,175,5:1
19Life-cycle management of construction projects based on virtual prototyping technology 显示文摘Guo H L Li Heng 2010Journal of Management in Engineering2010,26,1:1
20Prevalence of significant carotid stenosis in Chinese patient with peripheral and coronary artery disease显示文摘Heng SW Wu LL Lau H 1999Aust N Z J Surg1999,69,:1
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