维普中文期刊产品整合服务
3篇 您的检索式:作者名="HENRIK CARLSEN"
    题名 作者 年代 出处 被引量
1Barriers in municipal climate change adaptation: Results from case studies using backcasting 显示文摘CARLSSON - KANYAMA A CARLSEN H KARL - HENRIK D 2013(49) : 9 -212013,,49:1
2Numerical Study on Optimal Stirling Engine Regenerator Matrix Designs Taking into Account the efFects of Matrix Temperature Oscillations 显示文摘STIG KILDEGARD ANDERSEN HENRIK CARLSEN PER GROVE THOMSEN 2006Energy Conversion and Management2006,47,78:1
3MicroRNA-126 and epidermal growth factor-like domain 7 predict recurrence in patients with colon cancer treated with neoadjuvant chemotherapy显示文摘Aim:Neoadjuvant chemotherapy may represent a shift in the treatment of locally advanced colon cancer.The angiogenic couple has-microRNA-126(miRNA-126)and epidermal growth factor-like domain 7(EGFL7)are transcribed from the same gene and regulates all aspects of angiogenesis and may influence the ability of tumor cells to disseminate.The aim was to analyze the relationship between miRNA-126 and EGFL7 and disease recurrence in patients with locally advanced colon cancer treated with neoadjuvant chemotherapy.Methods:This study included 71 patients from a phase II study all planned for three cycles of capecitabine and oxaliplatin before surgery.Blood was sampled at baseline and right before and after the operation.Circulating miRNA-126 was analysed by RT-qPCR and a quantitative immunoassay was used for the analyses of EGFL7.Results:The rates of 5-year disease-free survival(DFS)and overall survival(OS)were 80%and 85%,respectively.The level of circulating miRNA-126 before the operation predicts recurrence,P=0.035.In patients with values below and above the median the recurrence rate was 31%and 4%,respectively.Similar results applied to EGFL7.A combined estimate identified a subgroup of patients(25 of 71)with no recurrence and a 5-year DFS and OS rate of 100%,respectively.Conclusion:MicroRNA-126 and EGFL7 are predictors for disease recurrence in patients with locally advanced colon cancer treated with neoadjuvant chemotherapy and may assist in selection of adjuvant chemotherapy.Torben Frøstrup Hansen Anting Liu Carlsen Julia Tanas Tanassi Ole Larsen Flemming Brandt Sørensen Lars Henrik Jensen Anders Jakobsen 2019Cancer Drug Resistance2019,2,3:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费