|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration显示文摘Age-related macular degeneration(AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040.Genetics,age,diabetes,gender,obesity,hypertension,race,hyperopia,iris-color,smoking,sun-light and pyroptosis have varying roles in AMD,but oxidative stress-induced inflammation remains a significant driver of pathobiology.Eye is a unique organ as it contains a remarkable oxygengradient that generates reactive oxygen species(ROS) which upregulates inflammatory pathways.ROS becomes a source of functional and morphological impairments in retinal pigment epithelium(RPE),endothelial cells and retinal ganglion cells.Reports demonstrated that hydrogen sulfide(H_2S) acts as a signaling molecule and that it may treat ailments.Therefore,we propose a novel hypothesis that H_2S may restore homeostasis in the eyes thereby reducing damage caused by oxidative injury and inflammation.Since H_2S has been shown to be a powerful antioxidant because of its free-radicals' inhibition properties in addition to its beneficial effects in age-relatedconditions,therefore,patients may benefit from H_2S salubrious effects not only by minimizing their oxidant and inflammatory injuries to retina but also by lowering retinal glutamate excitotoxicity. | Akash K George Mahavir Singh Rubens Petit Homme Avisek Majumder Harpal S SANDhu Suresh C Tyagi | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 2 | Stealth PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system 显示文摘 | Bazile D Prud' Homme C Bassoulet MT | 1995 | J Pharm Sci1995，84，4： | 1 |
| 3 | Reliable Real-Time Solution of Parameterized Partial Differential Equations:Reduced-basis Output Bound显示文摘 | Prud'homme C Rovas D V Veroy K | 2002 | Journal of Fluids Engineering2002，124，： | 1 |
| 4 | Sensitivity of maximal aerobic power to training is genotype-dependent 显示文摘 | Prud'homme D Bouchard C Leblanc C | 1984 | Med Sei Sports Exerc1984，16，5： | 1 |
| 5 | Kinetics of hydrolysis of fructooligosaccharides in mineral buffered aqueous solutions:influence of pH and temperature显示文摘 | L'HOMME C ARBELOT M PUIGSERVER A | 2003 | Journal of Agricultural and Food Chemistry2003，51，1： | 1 |
| 6 | Heterogeneous Beliefs and Routes to Chaos in a Simple Asset Pricing Model显示文摘 | BROCK W A HOMMES C H | 1998 | Jour- nal of Economic Dynamics and Control1998，22，： | 1 |
| 7 | Resolution of Chaos with Application to Modified Samuelson Model显示文摘 | Hommes C H | 1990 | Journal of Economic Dynamics and Control1990，14，1： | 1 |
| 8 | Financial Markets as Nonlinear Adaptive Evolutionary Systems 显示文摘 | Hommes C | 2001 | Quantitative Finance2001，，1： | 1 |
| 9 | Moleculer mechanisms of glucocorticoid action and selective glucocorticoid eceptor agonists 显示文摘 | Stahn C L~wenberg M Hommes DW | 2007 | Mol Cell Endocrino12007，275，12： | 1 |
| 10 | Heterogeneous Agent Models in Economics and Finance 显示文摘 | HOMMES C H | 2006 | Handbook of Computational Economics2006，2，： | 1 |
| 11 | Complete primary sequences of two lambda immunoglobulin light chains in myelomas with nonamyloid(Randall-type) light chain deposition disease显示文摘 | Decourt C Touchard G Preud′homme JL | 1998 | Am J Pathol1998，153，1： | 1 |
| 12 | Terminology During the Past Decade(1994-2004)显示文摘 | L' Homme Marie-Claude Heid Ulrich & Sager Juan C | 1994 | Terminology 9:21994，2003，： | 1 |
| 13 | Heterogeneous beliefs and routes to chaos in a simple asset pricing model 显示文摘 | Brock W A Hommes C H | 1998 | Journal of Economic Dynamics and Control1998，22，89： | 1 |
| 14 | A com- plex systems approach to constructing better models for managing financial markets and the economy 显示文摘 | Doyne F Gallegati M Hommes C | 2012 | The European Physical Journal Special Topics2012，，1： | 1 |
| 15 | Heterogeneous beliefs androutes to chaos in a simple asset pricing model显示文摘 | BROCK W A HOMMES C H | 1998 | Journalof Economic Dynamics&Control1998，22，89： | 1 |
| 16 | Novel insights into mechanisms of glucecorticoid action and the development of new glucocorticoid receptor ligands显示文摘 | LOWENBETG M STAHN C HOMMES DW | 2008 | Steroids2008，73，： | 1 |
| 17 | Association of physical activity and bone: influence of vitamin D receptor genotype 显示文摘 | Blancher C Giguere Y Prud'homme D | 2002 | Med Sci Sports Exert2002，34，1： | 1 |
| 18 | Use of wireless cap- sule endoscopy in the management of severe Henoeh-Sehonlein purpu- ra显示文摘 | Preud'Homme DL Michail S Hodges C | 2006 | Pediatrics2006，118，3： | 1 |
| 19 | Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists显示文摘 | Stahn C L?wenberg M Hommes DW | | 0，，1： | 1 |
| 20 | Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists显示文摘 | STAHN C LOWENBERG M HOMMES DW | 2007 | Mol Cell Endocrinol2007，275，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员