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1Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas.Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan 2014World Journal of Gastroenterology2014,20,46:21
2Dynamic analysis of a flexible hub-beam system with tip mass显示文摘Cai G P Hong J Z Yang S X 2005Mechanics Research Communications2005,32,2:1
3Corrosion control methods in supercritical water oxidation and gasification processes显示文摘Marronea P A Hong G T 2009Supercritical Fluids2009,,51:1
4Corrosion control methods in supercritical water oxidation and gasification process 显示文摘Marrone P A Hong G T 2009The Journal of Supercritical Fluids2009,51,2:1
5A novel design of an air-core type permanent magnet linear brushless motor by space harmonics field analysis显示文摘KANG G H HONG J P KIM G T 2001IEEE Transaetiolas on Magnetics2001,37,5:1
6The effects of high pressure and various binders on the physico-chemical properties of restructured pork meat 显示文摘HONG G P PARK S H KIM J Y 2006Asian-Australasian Journal of Animal Sciences2006,19,10:1
7Modeling study of a flexible hub beam system with large motion and with considering the effect of shear deformation显示文摘You C L Hong J Z Cai G P 2006Journal of Vibration and Acoustics2006,,295:1
8Overexpression of △1-pyrroline-5-carboxylate synthetase increases proline over production and confers osmo-tolerance in transgenic plants 显示文摘Kavi Kishor P B K Hong Z Miao G 1995Plant Physiology1995,108,4:1
9Overexpression of Dlpyrroline-5-carboxylate synthetase increases proline production and confers osmotolerance in transgenic plants 显示文摘Kishor B P K Hong Z Miao G H 1995Plant Physiology1995,108,:1
10Takot subo cardiomyopathy (left ventricular ballooning syn drome) induced during dobutamine stress echocardio graphy显示文摘SILBERBAUER J HONG P LLOYD G W 2008Eur J Echocardiogr2008,9,:1
11Overexpression of △-Pyrroline-5-carboxylate synthetase increse proline production and confers osmotolerance in transgenic plants 显示文摘 Hong Z Miao G H 1987Plant Physiol1987,83,:1
12A Study of Adsorption Kinetics and Thermodynamics of ω-Mercaptoalkylhydroquinone Self-Assembled Monolayer on a Gold Electrode显示文摘Hong H G Wonchoul P 2005Electrochimica Acta2005,51,4:1
13Overcxpression of pyrroline-5-carboxylase synthasc increase proline production and confers osmotolerance in transgenic plants显示文摘Kishor P B K Hong Z Miao G 1995Plant Physiol1995,108,:1
14Over expression of △-pyrroline-5-carb oxylate synthetase increases proline production and confers osmotolerance in transgenic plants显示文摘Kavi Kishor P B Hong Z Miao G H Hu C A Verma D P S 1995Plant Physiol1995,108,:1
15Effect of 1- phenylsulfonyl]-3-(trans-4-methyl- cyclohexyl) urea( 14 ), a new synthetic sulfonylurea compound, on glucose metabolism in vivo and in vitro 显示文摘Wu G Z Hong G Zhang W P 2009Rzneimittelforschung2009,59,11:1
16High production of lacca- se by a new basidiomycete, Trametes sp显示文摘Tong P G Hong Y Z Xiao Y Z 2007Biotechnol Lett2007,29,:1
17Relationship between structural properties and CO2 capture performance of CaO-based sorbents obtained from different organometallic precursors 显示文摘LU Hong KHAN A SMIRNIOTIS P G 2008Industrial & Engineering Chemistry Research2008,47,16:1
18Multi-category micro-milling tool wear monitoring with continuous hidden Markov models 显示文摘Zhu K P Wong Y S Hong G S 2009Mechanical Systems and Signal Processing2009,23,2:1
19The amylose content in rice endosperm is related to the post-transcriptional regulation of the waxy gene显示文摘Wang Z Y Zheng F Q Shen G Z Gao J P Snusted D P Li M G Zhang J L Hong M M 1995The Plant Journal1995,7,4:1
20Over expression of D1-pyrroline-5-car-boxylate synthetase increases proline production and confers osmotolerance in transgenic plants显示文摘Kavi-Kishor P B K Hong Z Miao G H Hu C A A Verma D P S 1995Plant physiol1995,108,:1
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