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| 1 | MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer显示文摘Despite tremendous efforts from scientists and clinicians worldwide, pancreatic adenocarcinoma(PDAC) remains a deadly disease due to the lack of early diagnostic tools and reliable therapeutic approaches. Consequently, a majority of patients(80%) display an advanced disease that results in a low resection rate leading to an overall median survival of less than 6 months. Accordingly, robust markers for the early diagnosis and prognosis of pancreatic cancer, or markers indicative of survival and/or metastatic disease are des-perately needed to help alleviate the dismal prognosis of this cancer. In addition, the discovery of new therapeutic targets is mandatory to design effective treatments. In this review, we will highlight the translational studies demonstrating that microRNAs may soon translate into clinical applications as long-awaited screening tools and therapeutic targets for PDAC. | Marion Gayral Sébastien Jo Naima Hanoun Alix Vignolle-Vidoni Hubert Lulka Yannick Delpu Aline Meulle Marlène Dufresne Marine Humeau Maёl Chalret du Rieu Barbara Bournet Janick Sèlves Rosine Guimbaud Nicolas Carrère Louis Buscail Jérome Torrisani Pierre Cordelier | 2014 | World Journal of Gastroenterology2014，20，32： | 4 |
| 2 | Computer controlled of bladder pressue in the prevention of TUR syndrome:A randomized sdudy of 53 cases显示文摘 | Hubert J Cormier L Gerband PF | 1996 | Br J Urol1996，78，： | 1 |
| 3 | Chalcopyrite thin film solar cells by electrodeposition 显示文摘 | LINCOT D GUILLEMOLESA J F TAUNIER S GUIMARD D SICX-KURDI J CHAUMONT A ROUSSEL O RAMDANI O HUBERT C FAUVARQUE J P BODEREAU N PARISSI L PANHELEUX P FANOUILLERE P NAGHAVI N GRAND P P BENFARAH M MOGENSEN P KERREC O | 2004 | Solar Energy2004，77，： | 1 |
| 4 | Influence of the muco- sal epithelium microenvironment on Langerhans cells: implica- tions for the development of squamous intraepithelial lesions of the cervix显示文摘 | Giannini S L Hubert P Doyen J | 2002 | Int J Cancer2002，97，5： | 1 |
| 5 | Three-dimensional CT-scan reconstruction of renal calculi: A new tool for mappingout staghorn calculi and follow-up of radiolucent stones 显示文摘 | HUBERT J BLUM A CORMIER L | 1997 | Eur Urol1997，31，3： | 1 |
| 6 | Effect of hydrocarbon stap- ling on the properties of alpha - helical antimicrobial peptides isolated from the venom of hymenoptera 显示文摘 | Hubert C Slaninova J Bednarova L | 2012 | Amino Acids2012，43，5： | 1 |
| 7 | 白细胞端粒长度缩短较动脉粥样硬化的临床表现提前出现:血液和肌肉模型显示文摘白细胞端粒长度与动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)相关。目前还不清楚这种关系是否源于出生时天生较短的白细胞端粒长度(leukocy tetelomere length,LTL)和(或)之后较快的LTL消耗。LTL代表高增殖性造血系统中的端粒长度,而骨骼肌中的端粒长度(muscle tetelomere length,MTL)代表最低限度复制的组织。 | Benetos A Toupance S Gautier S Labat C Kimura M Rossi PM Settembre N Hubert J Frimat L Bertrand B Boufi M Flecher X Sadoul N Eschwege P Kessler ML Tzanetakou IP Doulamis IP Konstantopoulos PS Tzani AI Korou LM Gkogkos A Perreas KG Menenakos E Samanidis G Vasiloglou-Gkanis M Kark JD Malikov S Verhulst S Aviv A 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，1： | 1 |
| 8 | Generalized procedures for evaluating spatial autocorrela- tion显示文摘 | HUBERT L J GOLLEDGE R G CONSTANZO C M | 1981 | Geographical Analysis1981，，12： | 1 |
| 9 | Computer controlled of bladder presses in the preventinnon of TUB syndrome:Arandomized study of 53 cases显示文摘 | Hubert J cormier L gerband PF | 1996 | Br J Urol1996，78，2： | 1 |
| 10 | Aquatic ecological risks due to cyanide releases from biomass burning显示文摘 | Timothy R. Barber Christopher C Lutes Michiel R.J Doorn Phyllis C Fuchsman Hubert J Timmenga Robert L Crouch | 2002 | Chemosphere2002，，3： | 1 |
| 11 | Resistance gene signaling in plants-complex similarities to animal innate immunity 显示文摘 | Holt III B F Hubert D A Dangl J L | 2003 | Current Opinion in Immunology2003，15，1： | 1 |
| 12 | Source Localization by Spatially Distributed Electronic Noses for Advection and Diffusion显示文摘 | Matthes J Groll L Hubert B K | 2005 | Signal Processing IEEE Transactions on[See Also Acoustics Speech and Signal Processing IEEE Transactions on]2005，53，5： | 1 |
| 13 | Patency of autogenous and polytet-rafluoroethylene upper extremity arteriovenous hemodialysis accessed: a systematic review 显示文摘 | HUBERT S CARTER J W CARTER R L | 2003 | J Vasc Surg2003，38，5： | 1 |
| 14 | Optimal Weighting of Networked Electronic Noses for the Source Localization显示文摘 | Matthes J Groll L Hubert B K | 2005 | Proceedings of the 2005 Systems Communications2005，，： | 1 |
| 15 | A high-power Kaband quasi-optical amplifier array 显示文摘 | Ortiz S C Hubert J Mirth L | 2002 | IEEE Trans on MTr2002，50，2： | 1 |
| 16 | Computer controlled monitoing or bladder pressure in the prevention of TUR syndrome: a randomized study of 53 cases显示文摘 | Cormier L Gerbaud P F | 1996 | Br J Urol1996，78，： | 1 |
| 17 | A High- Power Ka-Band Quasi-Optical Amplifier Array 显示文摘 | ORTIZ S C HUBERT J MIRTH L | 2002 | IEEE Trans on Microwave Theory and Techniques2002，50，2： | 1 |
| 18 | Computer controlled of bladder pressue in the prevention of TUB syndrome:A randomized Study of 53 cases显示文摘 | HUBERT J CORMIER L GERBAND PF | 1996 | Br J Urol1996，78，： | 1 |
| 19 | Computer-controlled monitoring of bladder pressure in the prevention of 'TUR syndrome':a randomized study of 53 cases显示文摘 | Hubert J Cormier L Gerbaud PF | | 0，，02： | 1 |
| 20 | Endoscopic implantation of a biopolymer in the lower esophageal sphincter for gastroesophageal efflux:a pilot study显示文摘 | Deviere J Alfredo P Hubert L | 2002 | Gastrointestinal Endoscoyp2002，55，： | 1 |
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