维普中文期刊产品整合服务
15篇 您的检索式:作者名="HUIMIN T"
    题名 作者 年代 出处 被引量
1TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang 2016Cell Research2016,26,9:13
2The relationship between managerial ownership and firm performance in high R&D firms显示文摘Cui Huimin Mak Y T 0,,:1
3Development and validation of a multi-residue screening method for veterinary drugs,their metabolites and pesticides in meat using liquid chromatography-tandem mass spectrometry显示文摘Huimin W Yanfei T Dongmei C 2009Analytica Chimica Acta2009,637,12:1
4The Relationship Between Managerial Ownership and Firm Performance in High R&D Firms显示文摘Huimin Cui Y T Mak 2002Journal of Corporate Finance2002,8,4:1
5The relationship between managerial ownership and firm performance in high R&D firms 显示文摘Huimin Cui Mak Y T 2002Journal of Corporate Finance2002,,8:1
6The relationship between managerial ownership and firm performance in high R:D firms 显示文摘CUI Huimin MAK Y T 2002Journal of Corporate Finance2002,,8:1
7The Relationship between Managerial Ownership and Firm Performance in High R&D Firms显示文摘Huimin C Y T Mak 2002Journal of Corporate Finance2002,,8:1
8Performance limits of track-to-track fusion versus centralized estimation: theory and application 显示文摘Chen Huimin Kirubarajan T Bar-Shalom Y 2003IEEE Transactions on Aerospace and Electronic Systems2003,39,2:1
9Estimation of GARCH models from the autocorrelations of the squares of a process显示文摘BAILLIE R T HUIMIN C 2001Journal of Time Series Analysis2001,22,6:1
10Nutritional regulation of mRNA processing显示文摘LISA M S WIOLETTA S F HUIMIN T 2004J Nutr2004,134,:1
11Tracking of spawning targets with multiple finite resolution sensors 显示文摘Chert Huimin Y Bar-Shalom T Kirubarajan 2008IEEE Transactions on Aerospace and Electronic Systems2008,44,1:1
12Tracking of Spawning Targets with Multiple Finite Resolution Sensors显示文摘Chen Huimin Bar-Shalom Y Kirubarajan T 2008IEEE Trans on Aerospace and Electronic Systems2008,44,1:1
13Screw fixation via diploicbone paralleling to occiput table:anatomical analysis of a newtechnique and report of 11 cases显示文摘Mingsheng T Huimin W Xin J 2007Eur Spine J2007,16,12:1
14Screw fixation via di-ploic bone paralleling to occiput table : anatomical analysis of anew technique and report of 11 cases 显示文摘Mingsheng T Huimin W Xin J 2007Eur Spine J2007,16,12:1
15Comparative study between core-shell and interpenetrating network structure polyurethane/polyacrylate composite emulsions 显示文摘Shuling C Martinming J Huimin T 2001Progress in Organic Coatings2001,43,:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费