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| 1 | Effect of ginseng polysaccharides and dendritic cells on the balance of Th1/Th2 T helper cells in patients with non-small cell lung cancer显示文摘OBJECTIVE: To investigate the effect of thorascopic administration of ginseng polysaccharides(GPS)plus dendritic cells(DC) on T helper cell type 1/T helper cell type 2(Th1/Th2) balance in patients with non-small cell lung cancer(NSCLC).METHODS: A total of 96 NSCLC patients were divided evenly into two groups. The control group was treated with DCs alone and the treatment group was treated with DCs plus GPS. After DCs and GPS were administered thoracoscopically, once a week,4 times for 30 days, the patients' quality of life was measured with the Functional Assessment of Can-cer Treatment-Lung(FACT-L) questionnaire before and after treatment. Serum interferon-γ(INF-γ), interleukin-4(IL-4), IL-2 and IL-5 were examined before and after treatments.RESULTS: The level of Th1 cytokines(INF-γ, IL-2)and the ratio of Th1/Th2 cytokines(INF-γ/IL-4, IL-2/IL-5) increased in both treatment groups, while Th2cytokines(IL-4, IL-5) and FACT-L scores decreased(P<0.01). Furthermore, after treatment Th1 cytokines(INF-γ, IL-2) and the ratio of Th1/Th2 cytokines(INF-γ/IL-4, IL-2/IL-5) were higher in the DCs +GPS group than in the control group(P<0.05). Conversely, FACT-L scores and Th2 cytokines(IL-4, IL-5)were higher in the control group than in the DCs +GPS group(P<0.05).CONCLUSION: The treatment regime of DCs plus GPS had a greater effect on NSCLC patients' immune function as compared with DCs alone. This was evident by increased expression of Th1 cytokines(INF-γ, IL-2) and the ratio of Th1/Th2(INF-γ/IL-4, IL-2/IL-5), as well as by decreased FACT-L scores and the expression of Th2 cytokines(IL-4,IL-5). | Junjie Ma Huiping Liu Xiaolong Wang | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 41 |
| 2 | Metadynamic Recrystallization of the As-cast 42CrMo Steel after Normalizing and Tempering during Hot Compression显示文摘The existing researches of hot ring rolling process are mainly based on forged billet. Compared with the existing process, the new ring casting-rolling compound forming process has significant advantages in saving materials and energy, reducing emission and reducing the production cost. The microstructure evolution of the casting materials during hot deformation is the basis of the research of the new process. However, the researches on the casting materials are rare. The metadynamic recrystallization of the as-cast 42CrMo steel after normalizing and tempering during the hot compression is investigated. The tests are performed on the Gleeble-1500 thermal-mechanical simulator. The influence rule of the deformation parameters on the metadynamic recrystallization is obtained by analyzing the experimental data. The kinetic model of the metadynamic recrystallization is deduced. The analysis results show that the metadynamic recrystallization fraction increases with the increase of the deformation temperature and the strain rate. The metallographic experiments are used to investigate the influence rule of the deformation parameters on the grain size of the metadynamic recrystallization. The experimental results show that the grain of the metadynamic recrystallization could be refined with the increase of the strain rate and the decrease of the deformation temperature during hot compression. The occurrence of the metadynamic recrystallization during the hot deformation is more difficult in as-cast 42CrMo steel than in forged 42CrMo steel. The research can provide the foundation for the further research of the hot deformation behaviors of the as-cast structure and theoretical support for the new ring casting-rolling compound process. | QI Huiping LI Yongtang | 2012 | Chinese Journal of Mechanical Engineering2012，25，5： | 19 |
| 3 | Retrospective epidemiological study of thyroid nodules by ultrasound in asymptomatic subjects显示文摘 | Sharen Gaowa Zhang Bo Zhao Ruina Sun Jie Gai Xiaorong Lou Huiping | 2014 | Chinese Medical Journal2014，，9： | 17 |
| 4 | The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice显示文摘动脉粥样硬化(作为) 疾病被多重因素导致,包括基因、环境的元素。现在的学习的目的是在致病上调查高胆固醇,高蛋氨酸食谱,和 apolipoprotein E 缺乏(ApoE/) 的全面效果作为。ApoE/ 老鼠用高胆固醇和蛋氨酸饮食被喂 15 个星期导致 hyperlipidemia 和 hyperhomocysteinemia。genomic DNA (gDNA ) 和 B1 的 methylation 层次在大动脉的纸巾的重复元素被两 methylation 依赖的限制分析测量并且嵌套 methylation 特定的聚合酶链反应(PCR ) 。Methylation 顺序偏爱模式是由有限制 endonuclease 消化的 DNA 接受甲基的能力的 assayed。DNA methyltransferase-1 的 mRNA 表示, 3 (DNMT1, 3 ) 被即时 PCR 检测。S-adenosylmethionine (SAM ) 和 S-adenosylhomocysteine (SAH ) 的集中被高效的液体层析决定。结果显示出 gDNA 和 B1 的 hypomethylation 重复元素。DNMT1 的 mRNA 表示被减少。SAM, SAH,和 SAM/SAH 比率的层次被增加。动脉粥样硬化患者损害区域强烈与风险因素相关。DNA demethylation 的分发被喜欢而不是 non-CpG 岛,它可以在 DNA 正直和 genomic 不稳定性上建议 hypomethylation 的主要影响。总的来说,我们的数据不含糊地证明高胆固醇,高蛋氨酸食谱,和 ApoE/ 的全面角色不与一个单个风险因素的角色一致地一致。DNA methylation 模式在这是相当复杂的并且取决于基因背景和许多深奥风险因素。 | Yideng Jiang Huiping Zhang Tao Sun Ju Wang Weiwei Sun Huihui Gong Binbin Yang Yingkang Shi Jun Wei | 2012 | Acta Biochimica et Biophysica Sinica2012，44，10： | 16 |
| 5 | Technology and Experiments of 42CrMo Bearing Ring Forming Based on Casting Ring Blank显示文摘Bearing ring is the crucial component of bearing. With regard to such problems as material waste, low efficiency and high energy consumption in current process of producing large bearing ring, a new process named 'casting-rolling compound forming technology' is researched by taking the typical 42CrMo slew bearing as object. Through theoretical analysis, the design criteria of the main casting-rolling forming parameters are put forward at first. Then the constitutive relationship model of as-cast 42CrMo steel and its mathematical model of dynamic recrystallization are obtained according to the results of the hot compression experiment. By a coupled thermal-mechanical finite element model for radial-axial rolling of bearing ring, the fraction of dynamic recrystallization is calculated and recrystallized grains size are predicated. Meanwhile, the effects of the initial rolling temperature and feed rate of idle roll on material microstructure evolution are analyzed. Finally, the industrial rolling experiment is designed and performed, based on the simulation results. In addition, mechanical and metallographic tests are conducted on rolled bearing ring to get the mechanical parameters and metallographic structure. The experimental data and results show that the mechanical properties of bearing ring produced by casting-rolling compound forming technology are up to industrial standard, and a qualified bearing ring can be successfully formed by employing this new technology. Through the study, a process of forming large bearing ring directly by using casting ring blank is obtained, which could provide an effective theoretical guidance for manufacturing large ring parts. It also has an edge in saving material, lowering energy and improving efficiency. | LI Yongtang JU Li QI Huiping ZHANG Feng CHEN Guozhen WANG Mingli | 2014 | Chinese Journal of Mechanical Engineering2014，27，2： | 16 |
| 6 | Microstructural characterization of titanium matrix composite coatings reinforced by in situ synthesized TiB + TiC fabricated on Ti6Al4V by laser cladding显示文摘Titanium-based composite coatings reinforced by in situ synthesized TiB and TiC particles between titanium and B4C were successfully fabricated on Ti6Al4V by laser cladding.Phase constituents of the coatings were predicted by thermodynamic calculations in the Ti-B4C-Al and Ti-B-C-Al systems,respectively,and were validated well by X-ray diffraction(XRD) analysis results.Microstructural and metallographic analyses were made by scanning electron microscopy(SEM) and electron probe micro-analysis(EPMA).The results show that the coatings are mainly composed of α-Ti cellular dendrites and the eutecticum in which a large number of needle-shaped TiB and a few equiaxial TiC particles are embedded.C is enriched in α-Ti cellular dendrites and far exceeds the theoretical maximum dissolubility,owing to the extension of saturation during laser cladding.The coatings have a good metallurgical bond with the substrate due to the existence of the dilution zone,in which a great amount of lamella β-Ti grains consisting of a thin needle-shaped martensitic microstructure are present and grow parallel to the heat flux direction;a few TiB and TiC reinforcements are observed at the boundaries of initial β-Ti grains. | LI Jun YU Zhishui WANG Huiping LI Manping | 2010 | Rare Metals2010，29，5： | 16 |
| 7 | Three-Dimensional Thermo-mechanical Coupled FEM Simulation for Hot Continuous Rolling of Large-Diameter Mandrel Bar显示文摘Based on the important boundary conditions of rolling simulation including friction, heat conduction and interactionsof the workpiece and rolls, the hot continuous rolling processes of large-diameter mandrel round bar (200 mm indiameter) in 6VH-stand hot tandem mill are successfully simulated by three-dimensional coupled thermomechanicalelastoplastic finite element method (FEM). The distributions of stress, strain, temperature and the rolling force andtorque for the two-pass and four-pass continuous rolling are calculated respectively. Thus, the two and four-passroll schedules are verified, respectively. The simulation results show that it is safe to produce 200 mm round barby the two-pass (oval pass and round pass) continuous rolling on the existing equipment compared to the four-passcontinuous rolling. There are concave surfaces and increased widths occurring at the end of rolled billet due touneven deformations between the outside and inside of the workpiece as well as the free spreading close to the rollgap of the final pass. | Huiping HONG Yonglin KANG Changtao FENG Xiqiang CHEN | 2003 | Journal of Materials Science & Technology2003，19，z1： | 13 |
| 8 | Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism显示文摘The liver is the central organ involved in lipid metabolism. Dyslipidemia and its related disorders, including non-alcoholic fatty liver disease(NAFLD), obesity and other metabolic diseases, are of increasing public health concern due to their increasing prevalence in the population. Besides their well-characterized functions in cholesterol homoeostasis and nutrient absorption, bile acids are also important metabolic regulators and function as signaling hormones by activating specific nuclear receptors, G-protein coupled receptors, and multiple signaling pathways. Recent studies identified a new signaling pathway by which conjugated bile acids(CBA) activate the extracellular regulated protein kinases(ERK1/2) and protein kinase B(AKT) signaling pathway via sphingosine-1-phosphate receptor 2(S1PR2). CBA-induced activation of S1PR2 is a key regulator of sphingosine kinase 2(Sph K2) andhepatic gene expression. This review focuses on recent findings related to the role of bile acids/S1PR2-mediated signaling pathways in regulating hepatic lipid metabolism. | Eric Kwong Yunzhou Li Phillip B.Hylemon Huiping Zhou | 2015 | Acta Pharmaceutica Sinica B2015，5，2： | 13 |
| 9 | Additive manufacturing of Ti-6Al-4V lattice structures with high structural integrity under large compressive deformation显示文摘Additively manufactured Ti-6 Al-4 V lattice structures have found important niche applications. However, they often show insufficient compressive ductility or insufficient structural integrity. In this study,a batch of 45 octahedral Ti-6 Al-4 V lattice structures was manufactured in three different strut diameters(0.5, 1.0, 1.5 mm) by selective electron beam melting(SEBM). The influence of post-SEBM annealing on the compressive deformation characteristics of the lattice structure was investigated. The as-built Ti-6 Al-4 V lattices fragmented when the compressive strain reached 13%–23% depending on strut diameter.Annealing at 950?C(β transus temperature: 995?C) only slightly improved the compressive ductility of the lattice structures. However, annealing at 1050?C(β-annealing) fundamentally changed the compressive deformation mode of the lattice structures. The resultant compressive stress-strain curve was featured by a long smooth plateau and no facture occurred even after significant densification of the lattice structure had taken place(>50% of compressive strain). | Kun Yang Jian Wang Liang Jia Guangyu Yang Huiping Tang Yuanyuan Li | 2019 | Journal of Materials Science & Technology2019，35，2： | 12 |
| 10 | Hyperhomocysteinemia induces cardiac injury by up-regulation of p53-dependent Noxa and Bax expression through the p53 DNA methylation in ApoE-/- mice显示文摘Hyperhomocysteinemia (HHcy ) 是为心血管的疾病的一个风险因素并且与心失败有强壮的关联。然而,心脏的织物上的 HHcy 的效果仍然保持不太好理解。阐明在导致 HHcy 的心脏的损害的 p53 依赖的 apoptosis 的角色,我们用高蛋氨酸饮食喂了 ApoE/ 老鼠建立 HHcy 模型。浆液 Hcy,心脏的酶,和类脂化合物被测量。Noxa, DNMT1, caspases-3/9,和 p53 的蛋白质层次被连接酶的 immunosorbent 试金决定。Bcl-2 和 Bax 蛋白质被染色的 immunohistochemistry 检测。S-adenosyl 蛋氨酸和 S-adenosyl homocysteine 集中被高效的液体层析决定。p53 和 DNMT1 的 mRNA 层次被即时聚合酶链反应(PCR ) 分析, p53 的 methylation 层次被嵌套的 methylation-specific-PCR 分析。我们的数据证明浆液 Hcy 和类脂化合物的集中与 N 控制组相比在 Meth 组被增加,它显示模型成功地被建立。p53 和 Noxa 的表示层次在 Meth 组被增加,当 p53 的 methylation 地位是 hypomethylation 时。caspase-3/9 的活动与 N 控制组相比在 Meth 组被增加。另外,染色的 immunohistochemistry 证明 Bax 的表示显著地与 N 控制组相比在 Meth 和 Meth-F 组被增加。在摘要, HHcy 由 p53 依赖的 pro-apoptotic 的起来规定导致心脏的损害联系了基因 Noxa 和 Bax,当 p53 DNA hypomethylation 是在 HHcy 导致的病理学的过程的关键分子的机制时。 | ShengchaoMa Huiping Zhang Weiwei Sun HuiHui Gong YanhuaWang Changjian Ma Ju Wang Chengjian Cao Xiaoling Yang Jue Tian Yideng Jiang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，5： | 12 |
| 11 | Performance of a completely autotrophic nitrogen removal over nitrite process for treating wastewater with different substrates at ambient temperature显示文摘The stability and parameters of a bio-ceramic filter for completely autotrophic nitrogen removal were investigated.The completely autotrophic nitrogen removal over nitrite(CANON) reactor was fed with different concentrations of ammonia(400,300,and 200mg N/L) but constant influent ammonia load.The results showed that the CANON system can achieve good treatment performance at ambient temperature(15-23°C).The average removal rate and removal loading of NH4+-N and TN was 83.90%,1.26kg N/(m3·day),and 70.14%,1.09kg N/(m3·day),respectively.Among the influencing factors like pH,dissolved oxygen and alkalinity,it was indicated that the pH was the key parameter of the performance of the CANON system.Observing the variation of pH would contribute to better control of the CANON system in an intuitive and fast way.Denaturing gradient gel electrophoresis analysis of microorganisms further revealed that there were some significant changes in the community structure of ammonium oxidizing bacteria,which had low diversity in different stages,while the species of anaerobic ammonium oxidizing(anammox) bacteria were fewer and the community composition was relatively stable.These observations showed that anaerobic ammonia oxidation was more stable than the aerobic ammonia oxidation,which could explain that why the CANON system maintained a good removal efficiency under the changing substrate conditions. | Xiaoyan Chang Dong Li Yuhai Liang Zhuo Yang Shaoming Cui Tao Liu Huiping Zeng Jie Zhang | 2013 | Journal of Environmental Sciences2013，25，4： | 12 |
| 12 | Efficacy and safety of trastuzumab combined with chemotherapy for first-line treatment and beyond progression of HER2-overexpressing advanced breast cancer显示文摘Objective: To observe the efficacy and safety of trastuzumab combined with chemotherapy in patients with human epidermal growth factor receptor 2(HER2)-overexpressing advanced breast cancer.Methods: A total of 90 patients with HER2-overexpressing advanced breast cancer were enrolled in this study. All patients were diagnosed with ductal invasive breast cancer by pathological analysis, and were aged between 31–73 years with a median of 51 years. HER2-positivity was defined as 3(+) staining in immunochemistry or amplification of fluorescence in situ hybridization(FISH, ratio ≥2.0). Trastuzumab was administered in combination with chemotherapy as first-line treatment and beyond progression as a secondline, third-line, and above treatment in 90, 34, 14, and 6 patients, respectively. The chemotherapy regimen was given according to normal clinical practice. The response rate was evaluated every two cycles, and the primary endpoints were progression-free survival(PFS) and overall survival(OS). Survival curves were estimated by using Kaplan-Meier graphs and were compared by using log-rank test statistics. Multivariate analysis was done using Cox's proportional hazards regression model, and the level of significance was P<0.05.Results: All 90 patients received at least one dose of trastuzumab, and efficacy could be evaluated in 85 patients. The median follow-up was 50 months. In total, 72(80.00%) patients had visceral metastasis, and 43(47.78%) patients had progressed after one or more extensive chemotherapy regimens for metastatic diseases. The median PFS for first-line trastuzumab was 10 months(range, 2–59 months), and the median OS after metastasis or initially local advanced disease was 22 months(range, 2–116 months).Conclusions: Trastuzumab combined with chemotherapy was active and well-tolerated as a first-line treatment and even beyond progression in HER2-overexpressing advanced breast cancer as a second-line or third-line treatment. However, its efficacy is certainly less beyond this point. | Huiping Li Bin Shao Yin Yan Guohong Song Xiaoran Liu Jing Wang Xu Liang | 2016 | Chinese Journal of Cancer Research2016，28，3： | 11 |
| 13 | Initiation and recession of the fluvial knickpoints:A case study from the Yalu River-Wangtian'e volcanic region,northeastern China显示文摘Initiation and recession of the knickpoints are significant boundary condition for processes of fluvial system.The distribution and recession rates of knickpoints contain information that provides a fundamental understanding of geomorphic processes.In the Yalu River-Wangtian'e volcanic region of northeastern China,broadly distributed flat lava terrain provides an ideal site to study the recession of fluvial knickpoints because knickpoints and waterfalls are well preserved here.Here we describe the distribution of knickpoints in the Yalu River-Wangtian'e volcanic region by combining DEM analysis and numerical modeling.Furthermore,we present a knickpoint celerity model,derived from stream-power incision model,to relate knickpoint recession rate to drainage area.We calibrate important empirical coefficients with our knickpoint celerity model;the best fit erosion coefficient (K) is 1.32×10 8,and the best fit drainage area exponent (m) is 0.69.Error analysis indicates a close correspondence between synthetic and real knickpoints.Finally,we show that knickpoint recession rates in the Yalu River-Wangtian'e volcanic region are ~1-10 mm/a during the early stages of transient incision,and that the present rates are ~1-6 mm/a.Our recession rate results are in good agreement with previous findings from the Aso Volcano and volcanoes near Boso Peninsula (Japan),which have a similar geologic history to the Yalu River-Wangtian'e volcanic region.Our present effort provides new insight into landscape evolution in the Yalu River-Wangtian'e volcanic region in northeastern China. | ZHANG HuiPing ZHANG PeiZhen FAN QiCheng | 2011 | Science China Earth Sciences2011，54，11： | 11 |
| 14 | Investigation of Dynamical Parameters of Exciton Confined in CdS Spherical Quantum Dots with a B—Spline Technique显示文摘Exciton energies as a function of radii of quantum dots in the range of 5-35 A are calculated based on effective mass approximation model with the B-spline technique and compared with experimental and other theoretical data for the CdS dots. This method leads to accurate and fast convergent exciton energy, which are in good agreement with experimental data in the whole confinement regime. The effect of penetration of wave function from the inside to the outside of the dots and the effect of dielectric constants are taken into account. The magnitudes of dynamical parameters are discussed. It is found that the different materials surrounding the CdS quantum dot affect not only the potential energy and Coulomb interaction energy of the system, but also the effective masses. The comparison shows that the effective mass approximation model can describe very well the quantum size effects observed experimentally on the exciton ground state energy. | HUIPing SHITing-Yun 等 | 2003 | Communications in Theoretical Physics2003，39，3： | 10 |
| 15 | The role of microRNAs in colorectal cancerr显示文摘MicroRNAs are small non-coding RNAs which regulate gene expression in a post-transcriptional manner. Although the first study was published about 15 years ago, knowledge about their role in regulation of cell proliferation, differentiation, apoptosis and immunity has been greatly advanced recently. Their association with formation, angiogenesis, metastasis and chemotherapy resistance of tumors has become one of the core issues in epigenetics of cancer. Here, we summarize the latest findings concerning microRNAs involved in dif-ferent signal pathways leading to colorectal cancer, introduce some new potential microRNAs as biomarkers in diagnosis and prognosis, and analyze its application in the treatment of cancer. | Mao Liu Huiping Chen | 2010 | Journal of Genetics and Genomics2010，37，6： | 10 |
| 16 | Coastal seafloor observatory at Xiaoqushan in the East China Sea显示文摘The seafloor observation system is becoming an important infrastructure for marine research because it is transforming oceanic research from temporal investigation to long term observation.The East China Sea coastal seafloor observatory,located between 30°31′44″N,122°15′12″E and 30°31′34″N,122°14′40″E,is constructed near the Xiaoqushan Island outside the Hangzhou Bay on the inner continental shelf of the East China Sea.The observatory is connected by a submarine optical fiber composite power cable that is more than one kilometer long and consists of a special junction box that transmits power and communication signals to different instruments.The special junction box has a variety of waterproof plugs and connects to three different instruments installed in a trawl preventer.The submarine optical fiber composite power cable is landed on the platform by The East China Sea Branch,State Oceanic Administration and the power is continuously supplied by the solar panels and solar battery on the top of the platform.The real time data are directly sent through the cable to the platform and are transmitted by CDMA wireless to the receiver at the State Key Laboratory of Marine Geology of Tongji University.Measurements at the observatory have been taken since April 20,2009 after installation and the results have been interpreted.The characteristics of the near bottom boundary are constrained by a sediment suspension model using portion of the observed data.In particular,discussion is provided on the sea surface height anomaly at Xiaoqushan Island influenced by the tsunami driven by the 2010 Earthquake in Chile.The successful establishment of the coastal seafloor observatory is the first step toward future development of seafloor observation systems in China.It not only accumulates experiences in technology and engineering,but also paves the way for performing important oceanic research using the long term continuous observation platform. | XU HuiPing ZHANG YanWei XU ChangWei LI JianRu LIU Ding QIN RuFu LUO ShenQian FAN DaiDu | 2011 | Chinese Science Bulletin2011，56，26： | 10 |
| 17 | Identification and screening of nitrogenefficient cotton genotypes under low and normal nitrogen environments at the seedling stage显示文摘Background: Large quantities of nitrogen(N) fertilizer applied to cotton cropping systems support high yields but cause adverse environmental impacts such as N_20 emission and water eutrophication. The development of cotton cultivars with higher N use efficiencies suitable for low-N conditions is therefore important for sustainable production. In this study, we evaluated 100 cotton genotypes in 2016 for N use efficiency and related traits at the seedling stage.Methods: Sand culture experiment was conducted with low N levels(0.01 g·kg^(-1)) or normal N levels(0.1 g·kg^(-1)).We investigated plant height, SPAD value(soil plant analysis development chlorophyll meter), dry weight, N accumulation, N utilization efficiency, and N uptake efficiency. Through descriptive statistics, principal component analysis and heatmap clustering analysis, we confirmed the evaluation index system of N-efficient genotypes and the classification of N-efficient genotypes.Results: Significant differences were observed among N levels and genotypes for all agronomic traits and N levels.Coefficients of variation varied greatly and ranged from 6.7~28.8 and 7.4~20.8 under low-N and normal-N treatment, respectively. All traits showed highly significant positive correlations with each other, except SPAD value.The principal components under both N levels were similar, showing that total dry weight, aboveground dry weight, total N accumulation, and N uptake efficiency were important components. We confirmed these four traits as suitable screening indexes for low N tolerance. Based on the results of heatmap clustering and scatter diagram analysis of N efficiency value, 10 genotypes were found low-N tolerant, in which five varieties were inefficient under both low and normal N conditions, while four varieties were found efficient under low-N conditions but inefficient under normal-N conditions. Only one variety was efficient under both low and normal-N conditions. Meanwhile, 20 genotypes were identified as low-N sensitive ones, in which 19 genotypes were inefficient under low-N conditions but efficient under normal-N conditions, one variety was inefficient under both low and normal-N conditions.Conclusion: We preliminarily identified Kashi as a low-N tolerant and N-efficient cotton genotype, and CCRI 64 as a lowN sensitive and N-inefficient cotton genotype. Further studies should be carried out to verify the yield and heritability effect of specific genotypes in the field. | ZHANG Hengheng FU Xiaoqiong WANG Xiangru GUI Huiping DONG Qiang PANG Nianchang WANG Zhun ZHANG Xiling SONG Meizhen | 2018 | Journal of Cotton Research2018，1，2： | 9 |
| 18 | Analysis of ecological quality in Lhasa Metropolitan Area during 1990-2017 based on remote sensing and Google Earth Engine platform显示文摘Based on a total of 519 images,the composite images with the lowest possible cloud cover were generated at pixel level with image synthesis method on Google Earth Engine(GEE)platform.The Remote Sensing Ecological Index(RSEI)was adopted,and calculated in an efficient way with the assistance of parallel cloud computing of the GEE platform.The RSEI was used in this paper to evaluate and monitor the eco-environmental quality of the Lhasa Metropolitan Area.Results show that:(1)The ecological quality is better in the west than in the east of Lhasa Metropolitan Area,with Lhasa as an approximate dividing point.The ecological quality improved and then deteriorated dramatically before 2000,with the mean RSEI value dropping from 0.51 to 0.46;the trend was followed by a gradual increase up until 2017,with the mean RSEI value increased from 0.46 to 0.55.(2)The RSEI is weakly and positively correlated with socioeconomic indicators.This indicates that the population growth and economic development did not negatively influence the ecological quality,but actually boosted it.(3)The GEE can serve as an efficient computing platform for the assessment and monitoring of eco-environmental quality in vast regions. | HUANG Huiping CHEN Wei ZHANG Yuan QIAO Lin DU Yunyan | 2021 | Journal of Geographical Sciences2021，31，2： | 9 |
| 19 | 组织间信任形成机制研究述评:过去、现在与未来展望显示文摘文章通过对相关文献的系统梳理和批判性回顾,首先厘清了现有研究在组织间信任的核心概念与构成要素、组织间信任形成的前因及其作用的情境条件等方面尚存在的重大争议和局限;其次,围绕这些有待解决的争议与分歧,对组织间信任的内涵与结构维度、组织间信任形成的前因过程和情境因素及其权变效应进行了系统述评;最后,提出了组织间信任形成机制研究的整合性框架,并从组织间信任的构念、假设、前因、动态演变和中国情境等方面展望了该领域未来的研究方向。 | 洪茹燕 郭斌 LI Huiping | 2019 | 重庆大学学报(社会科学版)2019，25，6： | 9 |
| 20 | Type Synthesis of 1T2R Parallel Mechanisms Using Structure Coupling-Reducing Method显示文摘Direct kinematics with analytic solutions is critical to the real-time control of parallel mechanisms.Therefore,the type synthesis of a mechanism having explicit form of forward kinematics has become a topic of interest.Based on this purpose,this paper deals with the type synthesis of 1T2R parallel mechanisms by investigating the topological structure coupling-reducing of the 3UPS&UP parallel mechanism.With the aid of the theory of mechanism topology,the analysis of the topological characteristics of the 3UPS&UP parallel mechanism is presented,which shows that there are highly coupled motions and constraints amongst the limbs of the mechanism.Three methods for structure coupling-reducing of the 3UPS&UP parallel mechanism are proposed,resulting in eight new types of 1T2R parallel mechanisms with one or zero coupling degree.One obtained parallel mechanism is taken as an example to demonstrate that a mechanism with zero coupling degree has an explicit form for forward kinematics.The process of type synthesis is in the order of permutation and combination;therefore,there are no omissions.This method is also appli cable to other configurations,and novel topological structures having simple forward kinematics can be obtained from an original mechanism via this method. | Haitao Liu Ke Xu Huiping Shen Xianlei Shan Tingli Yang | 2019 | Chinese Journal of Mechanical Engineering2019，32，5： | 9 |
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