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您的检索式：作者名="Han Gaowei"
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| 1 | Bioengineering of nano metal-organic frameworks for cancer immunotherapy显示文摘Immunotherapy techniques,such as immune checkpoint inhibitors,chimeric antigen receptor(CAR)T cell therapies and cancer vaccines,have been burgeoning with great success,particularly for specific cancer types.However,side effects with fatal risks,dysfunction in tumor microenvironment and low immune response rates remain the bottlenecks in immunotherapy.Nano metal-organic frameworks(nMOFs),with an accurate structure and a narrow size distribution,are emerging as a solution to these problems.In addition to their function of temporospatial delivery,a large library of their compositions,together with flexibility in chemical interaction and inherent immune efficacy,offers opportunities for various designs of nMOFs for immunotherapy.In this review,we overview state-of-the-art research on nMOFs-based immunotherapies as well as their combination with other therapies.We demonstrate that nMOFs are predominantly customized for vaccine delivery or tumor-microenvironment modulation.Finally,a prospect of nMOFs in cancer immunotherapy will be discussed. | Gaowei Chong Jie Zang Yi Han Runping Su Nopphon Weeranoppanant Haiqing Dong Yongyong Li | 2021 | Nano Research2021，14，5： | 2 |
| 2 | Sequential pattern mining with gap constraints for discovery of the software bug features显示文摘 | Zeng Qiang Chen Yuping Han Gaowei | 2014 | Journal of Computational Information Systems2014，10，2： | 1 |
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